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GO:0016829: lyase activity (Molecular function)

"Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring." [EC:4.-.-.-, ISBN:0198547684]


There are 13227 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_17 Arabidopsis thaliana 6.14 % 0.000151 0.001265
Cluster_48 Arabidopsis thaliana 6.18 % 2e-06 1.7e-05
Cluster_69 Arabidopsis thaliana 7.89 % 0.000114 0.001154
Cluster_154 Arabidopsis thaliana 4.2 % 0.006929 0.024068
Cluster_397 Arabidopsis thaliana 100.0 % 1e-06 5e-06
Cluster_56 Amborella trichopoda 3.16 % 0.000976 0.013545
Cluster_75 Amborella trichopoda 7.69 % 4.3e-05 0.000962
Cluster_387 Amborella trichopoda 50.0 % 0.011827 0.023655
Cluster_355 Amborella trichopoda 50.0 % 0.011827 0.035483
Cluster_94 Amborella trichopoda 10.31 % 0.0 0.0
Cluster_341 Amborella trichopoda 50.0 % 0.011827 0.022264
Cluster_8 Amborella trichopoda 4.41 % 0.000165 0.001992
Cluster_136 Cyanophora paradoxa 3.85 % 0.004414 0.019947
Cluster_171 Cyanophora paradoxa 3.97 % 0.001281 0.030534
Cluster_192 Cyanophora paradoxa 6.12 % 0.003746 0.033401
Cluster_96 Cyanophora paradoxa 5.66 % 0.004676 0.023982
Cluster_181 Cyanophora paradoxa 6.12 % 0.003746 0.024973
Cluster_64 Cyanophora paradoxa 4.55 % 0.00242 0.020463
Cluster_198 Cyanophora paradoxa 8.0 % 0.000288 0.003143
Cluster_72 Cyanophora paradoxa 4.26 % 2.8e-05 0.000771
Cluster_128 Gingko biloba 4.11 % 0.004842 0.035969
Cluster_348 Gingko biloba 50.0 % 0.009274 0.019619
Cluster_578 Gingko biloba 50.0 % 0.009274 0.020404
Cluster_588 Gingko biloba 33.33 % 0.013879 0.038862
Cluster_320 Gingko biloba 4.69 % 0.003344 0.026752
Cluster_21 Gingko biloba 4.88 % 0.000596 0.015081
Cluster_177 Gingko biloba 7.69 % 0.000103 0.004648
Cluster_94 Gingko biloba 3.7 % 0.001663 0.048564
Cluster_159 Gingko biloba 5.36 % 0.002286 0.006711
Cluster_19 Gingko biloba 4.0 % 0.005221 0.020755
Cluster_62 Gingko biloba 5.77 % 0.0 3e-06
Cluster_16 Gingko biloba 5.56 % 1.2e-05 0.000235
Cluster_52 Gingko biloba 3.03 % 0.011185 0.025494
Cluster_830 Zea mays 50.0 % 0.007586 0.032873
Cluster_579 Zea mays 25.0 % 0.015115 0.021161
Cluster_595 Zea mays 33.33 % 0.011358 0.026502
Cluster_208 Zea mays 3.85 % 3.1e-05 0.000811
Cluster_255 Zea mays 7.59 % 1e-06 3e-06
Cluster_318 Zea mays 3.17 % 0.024089 0.045676
Cluster_159 Zea mays 5.3 % 1e-06 1.5e-05
Cluster_240 Zea mays 3.9 % 0.003206 0.019007
Cluster_898 Zea mays 50.0 % 0.007586 0.035763
Cluster_17 Marchantia polymorpha 4.17 % 0.000252 0.00424
Cluster_79 Marchantia polymorpha 3.66 % 0.006749 0.044671
Cluster_81 Marchantia polymorpha 2.84 % 0.004368 0.024749
Cluster_333 Marchantia polymorpha 100.0 % 2.2e-05 5.8e-05
Cluster_140 Marchantia polymorpha 3.85 % 0.005876 0.049104
Cluster_4 Marchantia polymorpha 3.95 % 0.005466 0.01932
Cluster_19 Physcomitrella patens 1.43 % 0.000862 0.003503
Cluster_4 Physcomitrella patens 2.97 % 0.000101 0.00272
Cluster_83 Picea abies 5.33 % 0.000335 0.019765
Cluster_1028 Picea abies 50.0 % 0.008686 0.020846
Cluster_115 Picea abies 3.7 % 0.00132 0.015624
Cluster_342 Picea abies 10.62 % 0.0 0.0
Cluster_621 Picea abies 50.0 % 0.008686 0.037638
Cluster_504 Picea abies 4.84 % 0.002553 0.017635
Cluster_1330 Picea abies 50.0 % 0.008686 0.019108
Cluster_225 Picea abies 8.77 % 5e-06 6.8e-05
Cluster_1311 Picea abies 50.0 % 0.008686 0.013029
Cluster_864 Picea abies 33.33 % 0.013 0.030334
Cluster_63 Picea abies 3.75 % 0.005236 0.046492
Cluster_941 Picea abies 50.0 % 0.008686 0.013029
Cluster_269 Picea abies 3.16 % 0.000675 0.00385
Cluster_9 Picea abies 4.23 % 0.003748 0.036946
Cluster_58 Picea abies 6.67 % 0.001011 0.004629
Cluster_578 Picea abies 50.0 % 0.008686 0.028228
Cluster_1361 Picea abies 50.0 % 0.008686 0.026725
Cluster_137 Picea abies 9.38 % 0.0 0.0
Cluster_212 Picea abies 4.26 % 0.017939 0.044184
Cluster_81 Picea abies 3.32 % 1.2e-05 0.000498
Cluster_37 Picea abies 3.7 % 8.4e-05 0.002294
Cluster_476 Picea abies 10.61 % 0.0 0.0
Cluster_111 Picea abies 4.0 % 0.000993 0.019995
Cluster_48 Picea abies 5.0 % 0.000429 0.010021
Cluster_349 Picea abies 5.88 % 0.001456 0.011231
Cluster_194 Oryza sativa 2.89 % 0.001163 0.004774
Cluster_53 Oryza sativa 3.75 % 0.005728 0.020366
Cluster_145 Oryza sativa 8.33 % 6.6e-05 0.000489
Cluster_91 Oryza sativa 6.35 % 0.000193 0.004899
Cluster_82 Oryza sativa 2.53 % 0.002102 0.017124
Cluster_125 Oryza sativa 2.45 % 0.006479 0.008719
Cluster_135 Selaginella moellendorffii 3.7 % 0.008446 0.039748
Cluster_156 Solanum lycopersicum 3.57 % 0.000913 0.014112
Cluster_39 Solanum lycopersicum 10.24 % 0.0 0.0
Cluster_538 Solanum lycopersicum 33.33 % 0.015764 0.029674
Cluster_529 Solanum lycopersicum 50.0 % 0.010537 0.022738
Cluster_3 Vitis vinifera 9.76 % 0.0 1.7e-05
Cluster_139 Vitis vinifera 5.26 % 0.003615 0.034543
Cluster_21 Vitis vinifera 4.97 % 5.9e-05 0.001367
Cluster_223 Vitis vinifera 3.85 % 0.010847 0.029131
Cluster_401 Vitis vinifera 50.0 % 0.016406 0.045115
Cluster_133 Vitis vinifera 17.57 % 0.0 0.0
Cluster_38 Vitis vinifera 10.87 % 3.8e-05 0.001093
Cluster_417 Vitis vinifera 50.0 % 0.016406 0.036092
Cluster_427 Vitis vinifera 50.0 % 0.016406 0.036913
Cluster_5 Vitis vinifera 4.93 % 0.000181 0.005234
Cluster_154 Chlamydomonas reinhardtii 8.77 % 0.000191 0.000713
Cluster_198 Chlamydomonas reinhardtii 50.0 % 0.018627 0.032079
Cluster_61 Chlamydomonas reinhardtii 3.68 % 0.0021 0.01956
Cluster_98 Chlamydomonas reinhardtii 11.11 % 0.0 1e-06
Cluster_38 Chlamydomonas reinhardtii 15.62 % 0.0 0.0
Cluster_109 Chlamydomonas reinhardtii 9.6 % 0.0 0.0
Cluster_90 Chlamydomonas reinhardtii 6.99 % 0.0 0.0
Cluster_132 Chlamydomonas reinhardtii 10.42 % 8.4e-05 0.000136
Sequences (13227) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro and Family associations disabled for items with more than 5000 associated sequences !