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GO:0043765: T/G mismatch-specific endonuclease activity (Molecular function)

"Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine." [IMG:00606, SP:P09184]


There are 176 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Sequences (176) (download table)

InterPro Domains

GO Terms

Family Terms