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GO:0003918: DNA topoisomerase type II (ATP-hydrolyzing) activity (Molecular function)

"Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2." [PMID:8811192]


There are 2998 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_228 Arabidopsis thaliana 1.39 % 0.000946 0.021236
Cluster_74 Amborella trichopoda 0.95 % 0.000873 0.005603
Cluster_264 Amborella trichopoda 1.69 % 0.012892 0.04741
Cluster_24 Cyanophora paradoxa 1.8 % 0.000297 0.00146
Cluster_69 Cyanophora paradoxa 1.43 % 0.016884 0.042349
Cluster_151 Gingko biloba 2.35 % 6.2e-05 0.00072
Cluster_188 Gingko biloba 1.27 % 0.000216 0.000825
Cluster_115 Zea mays 1.69 % 1e-06 4e-06
Cluster_180 Zea mays 0.93 % 0.012922 0.041597
Cluster_352 Zea mays 1.08 % 0.011135 0.026381
Cluster_194 Picea abies 1.57 % 3.6e-05 0.000133
Cluster_84 Picea abies 0.47 % 0.01603 0.044441
Cluster_87 Oryza sativa 0.64 % 0.014803 0.038454
Cluster_141 Oryza sativa 0.53 % 0.017706 0.045814
Cluster_139 Solanum lycopersicum 1.75 % 0.006675 0.023128
Sequences (2998) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms