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GO:0005085: guanyl-nucleotide exchange factor activity (Molecular function)

"Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase." [GOC:kd, GOC:mah]


There are 5846 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_99 Arabidopsis thaliana 4.42 % 0.0 5e-06
Cluster_96 Arabidopsis thaliana 1.79 % 0.000873 0.006318
Cluster_214 Arabidopsis thaliana 2.15 % 0.004882 0.041124
Cluster_194 Amborella trichopoda 1.6 % 0.002391 0.028127
Cluster_39 Amborella trichopoda 1.17 % 0.004414 0.031959
Cluster_147 Gingko biloba 2.86 % 0.0 0.0
Cluster_195 Zea mays 4.55 % 0.000273 0.001775
Cluster_136 Zea mays 1.79 % 0.000108 0.000312
Cluster_144 Zea mays 1.9 % 0.001544 0.005265
Cluster_234 Zea mays 1.81 % 6e-06 4.2e-05
Cluster_271 Zea mays 4.17 % 0.000325 0.001512
Cluster_68 Marchantia polymorpha 1.28 % 7e-06 6e-05
Cluster_69 Marchantia polymorpha 1.43 % 0.014341 0.029906
Cluster_126 Physcomitrella patens 0.86 % 0.000506 0.007475
Cluster_115 Picea abies 1.85 % 0.00027 0.004503
Cluster_523 Picea abies 2.22 % 0.010084 0.03598
Cluster_471 Picea abies 2.86 % 0.000113 0.003906
Cluster_12 Oryza sativa 0.91 % 0.003496 0.016299
Cluster_274 Oryza sativa 4.17 % 0.000171 0.003041
Cluster_191 Oryza sativa 1.31 % 0.001715 0.013907
Cluster_48 Oryza sativa 0.75 % 0.005023 0.032951
Cluster_72 Oryza sativa 1.5 % 6.8e-05 0.000418
Cluster_79 Solanum lycopersicum 1.04 % 0.006181 0.019722
Cluster_262 Solanum lycopersicum 3.28 % 0.000648 0.004233
Cluster_238 Solanum lycopersicum 2.6 % 0.001029 0.015908
Cluster_123 Vitis vinifera 0.83 % 0.005136 0.023437
Cluster_54 Vitis vinifera 0.76 % 0.006179 0.025243
Cluster_95 Chlamydomonas reinhardtii 0.82 % 0.000555 0.025313
Cluster_26 Chlamydomonas reinhardtii 1.23 % 0.013635 0.046271
Sequences (5846) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro and Family associations disabled for items with more than 5000 associated sequences !