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GO:0005852: eukaryotic translation initiation factor 3 complex (Cellular component)

"A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs." [PMID:15904532]


There are 3367 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_122 Arabidopsis thaliana 7.25 % 0.0 0.0
Cluster_194 Amborella trichopoda 1.6 % 0.000206 0.010296
Cluster_245 Amborella trichopoda 1.16 % 0.015646 0.045466
Cluster_131 Cyanophora paradoxa 2.27 % 7.5e-05 0.001314
Cluster_56 Zea mays 2.06 % 0.000192 0.000589
Cluster_261 Zea mays 1.28 % 0.01676 0.034416
Cluster_7 Zea mays 1.64 % 0.013129 0.02703
Cluster_36 Marchantia polymorpha 0.93 % 0.0275 0.043147
Cluster_13 Marchantia polymorpha 2.36 % 3e-06 0.00019
Cluster_248 Physcomitrella patens 0.79 % 0.02325 0.038115
Cluster_95 Physcomitrella patens 3.26 % 0.0 2.9e-05
Cluster_486 Picea abies 1.2 % 0.012388 0.04026
Cluster_84 Picea abies 0.93 % 0.000458 0.001954
Cluster_94 Oryza sativa 0.99 % 0.000338 0.001267
Cluster_316 Oryza sativa 0.99 % 0.014279 0.029351
Cluster_34 Selaginella moellendorffii 1.72 % 0.002603 0.009905
Cluster_105 Solanum lycopersicum 1.03 % 0.000671 0.002737
Cluster_44 Vitis vinifera 1.89 % 0.000159 0.002252
Cluster_56 Chlamydomonas reinhardtii 3.51 % 0.0 0.0
Sequences (3367) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms