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GO:0008534: oxidized purine nucleobase lesion DNA N-glycosylase activity (Molecular function)

"Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site." [GOC:elh, PMID:11554296]


There are 305 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_145 Arabidopsis thaliana 0.56 % 0.006473 0.032081
Cluster_337 Gingko biloba 1.89 % 0.001283 0.045333
Cluster_168 Marchantia polymorpha 1.89 % 0.002729 0.03108
Cluster_470 Picea abies 2.13 % 0.000705 0.025922
Sequences (305) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms