AT4G31210

Description : DNA topoisomerase, type IA, core

Gene families : OG0003494 (Archaeplastida) Phylogenetic Tree(s): OG0003494_tree ,
OG_05_0003651 (LandPlants) Phylogenetic Tree(s): OG_05_0003651_tree ,
OG_06_0004734 (SeedPlants) Phylogenetic Tree(s): OG_06_0004734_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AT4G31210
Cluster	HCCA: Cluster_17

Target	Alias	Description	ECC score	Gene Family Method
AMTR_s00006p00253660	evm_27.TU.AmTr_v1...	Cell cycle.organelle machineries.DNA replication.type-Ia...	0.1	Archaeplastida
GSVIVT01035576001	No alias	Cell cycle.organelle machineries.DNA replication.type-Ia...	0.14	Archaeplastida
LOC_Os06g16980.1	No alias	type-Ia DNA topoisomerase	0.08	Archaeplastida
MA_10435445g0010	No alias	type-Ia DNA topoisomerase	0.02	Archaeplastida
Mp2g25830.1	No alias	type-Ia DNA topoisomerase	0.03	Archaeplastida
Pp3c23_11430V3.1	No alias	DNA topoisomerase, type IA, core	0.03	Archaeplastida
Solyc02g081910.2.1	No alias	type-Ia DNA topoisomerase	0.09	Archaeplastida
Zm00001e030979_P001	No alias	type-Ia DNA topoisomerase	0.03	Archaeplastida
Zm00001e036824_P001	No alias	type-Ia DNA topoisomerase	0.11	Archaeplastida

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	ISS	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003917	DNA topoisomerase type I activity	ISS	Interproscan
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006220	pyrimidine nucleotide metabolic process	None	Extended
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	ISS	Interproscan
BP	GO:0006268	DNA unwinding involved in DNA replication	ISS	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009165	nucleotide biosynthetic process	None	Extended
BP	GO:0009218	pyrimidine ribonucleotide metabolic process	None	Extended
BP	GO:0009220	pyrimidine ribonucleotide biosynthetic process	RCA	Interproscan
BP	GO:0009259	ribonucleotide metabolic process	None	Extended
BP	GO:0009260	ribonucleotide biosynthetic process	None	Extended
CC	GO:0009507	chloroplast	ISM	Interproscan
CC	GO:0009536	plastid	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0019693	ribose phosphate metabolic process	None	Extended
BP	GO:0032392	DNA geometric change	None	Extended
BP	GO:0032508	DNA duplex unwinding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046390	ribose phosphate biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0072527	pyrimidine-containing compound metabolic process	None	Extended
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
BP	GO:0090407	organophosphate biosynthetic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
BP	GO:1901137	carbohydrate derivative biosynthetic process	None	Extended
BP	GO:1901293	nucleoside phosphate biosynthetic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Neighborhood
CC	GO:0000229	cytoplasmic chromosome	IEP	Neighborhood
BP	GO:0000373	Group II intron splicing	IEP	Neighborhood
BP	GO:0000740	nuclear membrane fusion	IEP	Neighborhood
BP	GO:0003006	developmental process involved in reproduction	IEP	Neighborhood
MF	GO:0003678	DNA helicase activity	IEP	Neighborhood
MF	GO:0003862	3-isopropylmalate dehydrogenase activity	IEP	Neighborhood
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Neighborhood
MF	GO:0003896	DNA primase activity	IEP	Neighborhood
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Neighborhood
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEP	Neighborhood
MF	GO:0003937	IMP cyclohydrolase activity	IEP	Neighborhood
MF	GO:0004003	ATP-dependent DNA helicase activity	IEP	Neighborhood
MF	GO:0004072	aspartate kinase activity	IEP	Neighborhood
MF	GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	IEP	Neighborhood
MF	GO:0004386	helicase activity	IEP	Neighborhood
MF	GO:0004412	homoserine dehydrogenase activity	IEP	Neighborhood
MF	GO:0004518	nuclease activity	IEP	Neighborhood
MF	GO:0004519	endonuclease activity	IEP	Neighborhood
MF	GO:0004521	endoribonuclease activity	IEP	Neighborhood
MF	GO:0004540	ribonuclease activity	IEP	Neighborhood
MF	GO:0004556	alpha-amylase activity	IEP	Neighborhood
MF	GO:0004638	phosphoribosylaminoimidazole carboxylase activity	IEP	Neighborhood
MF	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	IEP	Neighborhood
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Neighborhood
MF	GO:0004820	glycine-tRNA ligase activity	IEP	Neighborhood
MF	GO:0004825	methionine-tRNA ligase activity	IEP	Neighborhood
MF	GO:0005524	ATP binding	IEP	Neighborhood
CC	GO:0005739	mitochondrion	IEP	Neighborhood
CC	GO:0005951	carbamoyl-phosphate synthase complex	IEP	Neighborhood
BP	GO:0006094	gluconeogenesis	IEP	Neighborhood
BP	GO:0006163	purine nucleotide metabolic process	IEP	Neighborhood
BP	GO:0006164	purine nucleotide biosynthetic process	IEP	Neighborhood
BP	GO:0006188	IMP biosynthetic process	IEP	Neighborhood
BP	GO:0006189	'de novo' IMP biosynthetic process	IEP	Neighborhood
BP	GO:0006264	mitochondrial DNA replication	IEP	Neighborhood
BP	GO:0006364	rRNA processing	IEP	Neighborhood
BP	GO:0006396	RNA processing	IEP	Neighborhood
BP	GO:0006399	tRNA metabolic process	IEP	Neighborhood
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Neighborhood
BP	GO:0006426	glycyl-tRNA aminoacylation	IEP	Neighborhood
BP	GO:0006457	protein folding	IEP	Neighborhood
BP	GO:0006458	'de novo' protein folding	IEP	Neighborhood
BP	GO:0006520	cellular amino acid metabolic process	IEP	Neighborhood
BP	GO:0006525	arginine metabolic process	IEP	Neighborhood
BP	GO:0006526	arginine biosynthetic process	IEP	Neighborhood
BP	GO:0006551	leucine metabolic process	IEP	Neighborhood
BP	GO:0006553	lysine metabolic process	IEP	Neighborhood
BP	GO:0006783	heme biosynthetic process	IEP	Neighborhood
BP	GO:0006886	intracellular protein transport	IEP	Neighborhood
BP	GO:0007010	cytoskeleton organization	IEP	Neighborhood
BP	GO:0007275	multicellular organism development	IEP	Neighborhood
BP	GO:0007349	cellularization	IEP	Neighborhood
MF	GO:0008026	ATP-dependent helicase activity	IEP	Neighborhood
BP	GO:0008033	tRNA processing	IEP	Neighborhood
MF	GO:0008094	DNA-dependent ATPase activity	IEP	Neighborhood
MF	GO:0008144	drug binding	IEP	Neighborhood
MF	GO:0008173	RNA methyltransferase activity	IEP	Neighborhood
MF	GO:0008237	metallopeptidase activity	IEP	Neighborhood
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Neighborhood
MF	GO:0008864	formyltetrahydrofolate deformylase activity	IEP	Neighborhood
BP	GO:0009066	aspartate family amino acid metabolic process	IEP	Neighborhood
BP	GO:0009067	aspartate family amino acid biosynthetic process	IEP	Neighborhood
BP	GO:0009081	branched-chain amino acid metabolic process	IEP	Neighborhood
BP	GO:0009082	branched-chain amino acid biosynthetic process	IEP	Neighborhood
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Neighborhood
BP	GO:0009085	lysine biosynthetic process	IEP	Neighborhood
BP	GO:0009089	lysine biosynthetic process via diaminopimelate	IEP	Neighborhood
BP	GO:0009098	leucine biosynthetic process	IEP	Neighborhood
BP	GO:0009303	rRNA transcription	IEP	Neighborhood
CC	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)	IEP	Neighborhood
BP	GO:0009451	RNA modification	IEP	Neighborhood
CC	GO:0009508	plastid chromosome	IEP	Neighborhood
CC	GO:0009526	plastid envelope	IEP	Neighborhood
CC	GO:0009532	plastid stroma	IEP	Neighborhood
BP	GO:0009558	embryo sac cellularization	IEP	Neighborhood
CC	GO:0009570	chloroplast stroma	IEP	Neighborhood
BP	GO:0009657	plastid organization	IEP	Neighborhood
BP	GO:0009658	chloroplast organization	IEP	Neighborhood
BP	GO:0009704	de-etiolation	IEP	Neighborhood
BP	GO:0009790	embryo development	IEP	Neighborhood
BP	GO:0009793	embryo development ending in seed dormancy	IEP	Neighborhood
CC	GO:0009941	chloroplast envelope	IEP	Neighborhood
CC	GO:0010006	Toc complex	IEP	Neighborhood
BP	GO:0010020	chloroplast fission	IEP	Neighborhood
BP	GO:0010157	response to chlorate	IEP	Neighborhood
BP	GO:0010197	polar nucleus fusion	IEP	Neighborhood
BP	GO:0010198	synergid death	IEP	Neighborhood
MF	GO:0010285	L,L-diaminopimelate aminotransferase activity	IEP	Neighborhood
BP	GO:0010623	programmed cell death involved in cell development	IEP	Neighborhood
BP	GO:0015031	protein transport	IEP	Neighborhood
BP	GO:0016070	RNA metabolic process	IEP	Neighborhood
BP	GO:0016072	rRNA metabolic process	IEP	Neighborhood
MF	GO:0016160	amylase activity	IEP	Neighborhood
MF	GO:0016462	pyrophosphatase activity	IEP	Neighborhood
BP	GO:0016485	protein processing	IEP	Neighborhood
BP	GO:0016556	mRNA modification	IEP	Neighborhood
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	IEP	Neighborhood
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEP	Neighborhood
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Neighborhood
MF	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	IEP	Neighborhood
MF	GO:0016774	phosphotransferase activity, carboxyl group as acceptor	IEP	Neighborhood
MF	GO:0016779	nucleotidyltransferase activity	IEP	Neighborhood
MF	GO:0016787	hydrolase activity	IEP	Neighborhood
MF	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	IEP	Neighborhood
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	IEP	Neighborhood
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Neighborhood
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Neighborhood
MF	GO:0016874	ligase activity	IEP	Neighborhood
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Neighborhood
MF	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	IEP	Neighborhood
MF	GO:0016887	ATPase activity	IEP	Neighborhood
MF	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	IEP	Neighborhood
MF	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	IEP	Neighborhood
BP	GO:0017038	protein import	IEP	Neighborhood
MF	GO:0017076	purine nucleotide binding	IEP	Neighborhood
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Neighborhood
MF	GO:0019202	amino acid kinase activity	IEP	Neighborhood
MF	GO:0019238	cyclohydrolase activity	IEP	Neighborhood
BP	GO:0019319	hexose biosynthetic process	IEP	Neighborhood
MF	GO:0019843	rRNA binding	IEP	Neighborhood
BP	GO:0022414	reproductive process	IEP	Neighborhood
MF	GO:0030554	adenyl nucleotide binding	IEP	Neighborhood
BP	GO:0031123	RNA 3'-end processing	IEP	Neighborhood
CC	GO:0031350	intrinsic component of plastid membrane	IEP	Neighborhood
CC	GO:0031351	integral component of plastid membrane	IEP	Neighborhood
CC	GO:0031354	intrinsic component of plastid outer membrane	IEP	Neighborhood
CC	GO:0031355	integral component of plastid outer membrane	IEP	Neighborhood
CC	GO:0031358	intrinsic component of chloroplast outer membrane	IEP	Neighborhood
CC	GO:0031359	integral component of chloroplast outer membrane	IEP	Neighborhood
BP	GO:0031425	chloroplast RNA processing	IEP	Neighborhood
CC	GO:0031897	Tic complex	IEP	Neighborhood
CC	GO:0031967	organelle envelope	IEP	Neighborhood
CC	GO:0031975	envelope	IEP	Neighborhood
BP	GO:0032042	mitochondrial DNA metabolic process	IEP	Neighborhood
BP	GO:0032501	multicellular organismal process	IEP	Neighborhood
BP	GO:0032502	developmental process	IEP	Neighborhood
MF	GO:0032553	ribonucleotide binding	IEP	Neighborhood
MF	GO:0032555	purine ribonucleotide binding	IEP	Neighborhood
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Neighborhood
BP	GO:0033258	plastid DNA metabolic process	IEP	Neighborhood
BP	GO:0033259	plastid DNA replication	IEP	Neighborhood
BP	GO:0033365	protein localization to organelle	IEP	Neighborhood
MF	GO:0034061	DNA polymerase activity	IEP	Neighborhood
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Neighborhood
BP	GO:0034470	ncRNA processing	IEP	Neighborhood
BP	GO:0034660	ncRNA metabolic process	IEP	Neighborhood
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Neighborhood
MF	GO:0036094	small molecule binding	IEP	Neighborhood
MF	GO:0042623	ATPase activity, coupled	IEP	Neighborhood
BP	GO:0042780	tRNA 3'-end processing	IEP	Neighborhood
MF	GO:0042781	3'-tRNA processing endoribonuclease activity	IEP	Neighborhood
BP	GO:0042794	plastid rRNA transcription	IEP	Neighborhood
BP	GO:0043038	amino acid activation	IEP	Neighborhood
BP	GO:0043039	tRNA aminoacylation	IEP	Neighborhood
MF	GO:0043167	ion binding	IEP	Neighborhood
MF	GO:0043168	anion binding	IEP	Neighborhood
BP	GO:0043572	plastid fission	IEP	Neighborhood
MF	GO:0043621	protein self-association	IEP	Neighborhood
BP	GO:0043628	ncRNA 3'-end processing	IEP	Neighborhood
CC	GO:0044422	organelle part	IEP	Neighborhood
CC	GO:0044434	chloroplast part	IEP	Neighborhood
CC	GO:0044435	plastid part	IEP	Neighborhood
CC	GO:0044446	intracellular organelle part	IEP	Neighborhood
BP	GO:0045036	protein targeting to chloroplast	IEP	Neighborhood
BP	GO:0045037	protein import into chloroplast stroma	IEP	Neighborhood
BP	GO:0045184	establishment of protein localization	IEP	Neighborhood
BP	GO:0046040	IMP metabolic process	IEP	Neighborhood
BP	GO:0046451	diaminopimelate metabolic process	IEP	Neighborhood
BP	GO:0048229	gametophyte development	IEP	Neighborhood
BP	GO:0048285	organelle fission	IEP	Neighborhood
BP	GO:0048481	plant ovule development	IEP	Neighborhood
BP	GO:0048598	embryonic morphogenesis	IEP	Neighborhood
BP	GO:0048856	anatomical structure development	IEP	Neighborhood
BP	GO:0051084	'de novo' posttranslational protein folding	IEP	Neighborhood
BP	GO:0051085	chaperone cofactor-dependent protein refolding	IEP	Neighborhood
BP	GO:0051641	cellular localization	IEP	Neighborhood
BP	GO:0051649	establishment of localization in cell	IEP	Neighborhood
MF	GO:0052381	tRNA dimethylallyltransferase activity	IEP	Neighborhood
BP	GO:0055085	transmembrane transport	IEP	Neighborhood
BP	GO:0061025	membrane fusion	IEP	Neighborhood
BP	GO:0061077	chaperone-mediated protein folding	IEP	Neighborhood
MF	GO:0061505	DNA topoisomerase II activity	IEP	Neighborhood
BP	GO:0065002	intracellular protein transmembrane transport	IEP	Neighborhood
MF	GO:0070035	purine NTP-dependent helicase activity	IEP	Neighborhood
MF	GO:0070180	large ribosomal subunit rRNA binding	IEP	Neighborhood
BP	GO:0071806	protein transmembrane transport	IEP	Neighborhood
BP	GO:0072521	purine-containing compound metabolic process	IEP	Neighborhood
BP	GO:0072522	purine-containing compound biosynthetic process	IEP	Neighborhood
BP	GO:0072594	establishment of protein localization to organelle	IEP	Neighborhood
BP	GO:0072596	establishment of protein localization to chloroplast	IEP	Neighborhood
BP	GO:0072598	protein localization to chloroplast	IEP	Neighborhood
BP	GO:0080158	obsolete chloroplast ribulose bisphosphate carboxylase complex biogenesis	IEP	Neighborhood
BP	GO:0090174	organelle membrane fusion	IEP	Neighborhood
MF	GO:0097367	carbohydrate derivative binding	IEP	Neighborhood
MF	GO:0097747	RNA polymerase activity	IEP	Neighborhood
BP	GO:0098781	ncRNA transcription	IEP	Neighborhood
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Neighborhood
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Neighborhood
BP	GO:1901259	chloroplast rRNA processing	IEP	Neighborhood
MF	GO:1901265	nucleoside phosphate binding	IEP	Neighborhood
BP	GO:1901605	alpha-amino acid metabolic process	IEP	Neighborhood
BP	GO:1901607	alpha-amino acid biosynthetic process	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR006171	TOPRIM_domain	476	589
IPR025589	Toprim_C_rpt	1209	1258
IPR025589	Toprim_C_rpt	1148	1205
IPR013498	Topo_IA_Znf	1085	1121
IPR013497	Topo_IA_cen	604	1041

External Links

No external refs found!

AT4G31210

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation