AT5G05470 (ATEIF2-A2, EIF2-A2, EIF2 ALPHA)

Aliases : ATEIF2-A2, EIF2-A2, EIF2 ALPHA

Description : eukaryotic translation initiation factor 2 alpha subunit

Gene families : OG0004092 (Archaeplastida) Phylogenetic Tree(s): OG0004092_tree ,
OG_05_0003934 (LandPlants) Phylogenetic Tree(s): OG_05_0003934_tree ,
OG_06_0004013 (SeedPlants) Phylogenetic Tree(s): OG_06_0004013_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AT5G05470
Cluster	HCCA: Cluster_194

Target	Alias	Description	ECC score	Gene Family Method
AMTR_s00109p00125300	evm_27.TU.AmTr_v1...	Protein biosynthesis.translation...	0.03	Archaeplastida
GSVIVT01032762001	No alias	Protein biosynthesis.translation...	0.05	Archaeplastida
Gb_28065	No alias	component eIF2-alpha of eIF2 Met-tRNA binding factor complex	0.02	Archaeplastida
LOC_Os03g18510.1	No alias	component eIF2-alpha of eIF2 Met-tRNA binding factor complex	0.05	Archaeplastida
MA_12897g0020	No alias	component eIF2-alpha of eIF2 Met-tRNA binding factor complex	0.02	Archaeplastida
Solyc03g095840.3.1	No alias	component eIF2-alpha of eIF2 Met-tRNA binding factor complex	0.03	Archaeplastida

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003723	RNA binding	ISS	Interproscan
MF	GO:0003743	translation initiation factor activity	ISS	Interproscan
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	ISM	Interproscan
CC	GO:0005829	cytosol	IDA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006220	pyrimidine nucleotide metabolic process	None	Extended
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008135	translation factor activity, RNA binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009165	nucleotide biosynthetic process	None	Extended
BP	GO:0009218	pyrimidine ribonucleotide metabolic process	None	Extended
BP	GO:0009220	pyrimidine ribonucleotide biosynthetic process	RCA	Interproscan
BP	GO:0009259	ribonucleotide metabolic process	None	Extended
BP	GO:0009260	ribonucleotide biosynthetic process	None	Extended
BP	GO:0009314	response to radiation	None	Extended
BP	GO:0009416	response to light stimulus	None	Extended
BP	GO:0009628	response to abiotic stimulus	None	Extended
BP	GO:0009639	response to red or far red light	None	Extended
BP	GO:0009640	photomorphogenesis	RCA	Interproscan
BP	GO:0009791	post-embryonic development	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0019693	ribose phosphate metabolic process	None	Extended
BP	GO:0032501	multicellular organismal process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034654	nucleobase-containing compound biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046390	ribose phosphate biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072527	pyrimidine-containing compound metabolic process	None	Extended
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	None	Extended
BP	GO:0090407	organophosphate biosynthetic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
BP	GO:1901137	carbohydrate derivative biosynthetic process	None	Extended
BP	GO:1901293	nucleoside phosphate biosynthetic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000338	protein deneddylation	IEP	Neighborhood
BP	GO:0000373	Group II intron splicing	IEP	Neighborhood
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Neighborhood
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Neighborhood
BP	GO:0000741	karyogamy	IEP	Neighborhood
BP	GO:0000919	cell plate assembly	IEP	Neighborhood
BP	GO:0000959	mitochondrial RNA metabolic process	IEP	Neighborhood
BP	GO:0003006	developmental process involved in reproduction	IEP	Neighborhood
MF	GO:0003735	structural constituent of ribosome	IEP	Neighborhood
MF	GO:0003860	3-hydroxyisobutyryl-CoA hydrolase activity	IEP	Neighborhood
MF	GO:0003963	RNA-3'-phosphate cyclase activity	IEP	Neighborhood
MF	GO:0004146	dihydrofolate reductase activity	IEP	Neighborhood
MF	GO:0004484	mRNA guanylyltransferase activity	IEP	Neighborhood
MF	GO:0004576	oligosaccharyl transferase activity	IEP	Neighborhood
MF	GO:0004588	orotate phosphoribosyltransferase activity	IEP	Neighborhood
MF	GO:0004590	orotidine-5'-phosphate decarboxylase activity	IEP	Neighborhood
MF	GO:0004799	thymidylate synthase activity	IEP	Neighborhood
MF	GO:0004824	lysine-tRNA ligase activity	IEP	Neighborhood
MF	GO:0005198	structural molecule activity	IEP	Neighborhood
CC	GO:0005677	chromatin silencing complex	IEP	Neighborhood
CC	GO:0005739	mitochondrion	IEP	Neighborhood
CC	GO:0005741	mitochondrial outer membrane	IEP	Neighborhood
CC	GO:0005743	mitochondrial inner membrane	IEP	Neighborhood
BP	GO:0006259	DNA metabolic process	IEP	Neighborhood
BP	GO:0006310	DNA recombination	IEP	Neighborhood
BP	GO:0006325	chromatin organization	IEP	Neighborhood
BP	GO:0006370	7-methylguanosine mRNA capping	IEP	Neighborhood
BP	GO:0006397	mRNA processing	IEP	Neighborhood
BP	GO:0006405	RNA export from nucleus	IEP	Neighborhood
BP	GO:0006406	mRNA export from nucleus	IEP	Neighborhood
BP	GO:0006412	translation	IEP	Neighborhood
BP	GO:0006430	lysyl-tRNA aminoacylation	IEP	Neighborhood
BP	GO:0006446	regulation of translational initiation	IEP	Neighborhood
BP	GO:0006464	cellular protein modification process	IEP	Neighborhood
BP	GO:0006479	protein methylation	IEP	Neighborhood
BP	GO:0006518	peptide metabolic process	IEP	Neighborhood
BP	GO:0006605	protein targeting	IEP	Neighborhood
BP	GO:0006606	protein import into nucleus	IEP	Neighborhood
BP	GO:0006626	protein targeting to mitochondrion	IEP	Neighborhood
BP	GO:0006810	transport	IEP	Neighborhood
BP	GO:0006839	mitochondrial transport	IEP	Neighborhood
BP	GO:0006886	intracellular protein transport	IEP	Neighborhood
BP	GO:0006913	nucleocytoplasmic transport	IEP	Neighborhood
BP	GO:0007059	chromosome segregation	IEP	Neighborhood
BP	GO:0007062	sister chromatid cohesion	IEP	Neighborhood
BP	GO:0007129	synapsis	IEP	Neighborhood
BP	GO:0007131	reciprocal meiotic recombination	IEP	Neighborhood
BP	GO:0007275	multicellular organism development	IEP	Neighborhood
BP	GO:0008104	protein localization	IEP	Neighborhood
CC	GO:0008180	COP9 signalosome	IEP	Neighborhood
MF	GO:0008192	RNA guanylyltransferase activity	IEP	Neighborhood
BP	GO:0008213	protein alkylation	IEP	Neighborhood
MF	GO:0008252	nucleotidase activity	IEP	Neighborhood
MF	GO:0008253	5'-nucleotidase activity	IEP	Neighborhood
BP	GO:0008380	RNA splicing	IEP	Neighborhood
BP	GO:0009059	macromolecule biosynthetic process	IEP	Neighborhood
BP	GO:0009256	10-formyltetrahydrofolate metabolic process	IEP	Neighborhood
BP	GO:0009257	10-formyltetrahydrofolate biosynthetic process	IEP	Neighborhood
BP	GO:0009303	rRNA transcription	IEP	Neighborhood
BP	GO:0009396	folic acid-containing compound biosynthetic process	IEP	Neighborhood
BP	GO:0009452	7-methylguanosine RNA capping	IEP	Neighborhood
BP	GO:0009560	embryo sac egg cell differentiation	IEP	Neighborhood
BP	GO:0009756	carbohydrate mediated signaling	IEP	Neighborhood
BP	GO:0009845	seed germination	IEP	Neighborhood
BP	GO:0009909	regulation of flower development	IEP	Neighborhood
BP	GO:0009920	cell plate formation involved in plant-type cell wall biogenesis	IEP	Neighborhood
BP	GO:0009933	meristem structural organization	IEP	Neighborhood
MF	GO:0009975	cyclase activity	IEP	Neighborhood
MF	GO:0009982	pseudouridine synthase activity	IEP	Neighborhood
BP	GO:0010090	trichome morphogenesis	IEP	Neighborhood
BP	GO:0010162	seed dormancy process	IEP	Neighborhood
BP	GO:0010182	sugar mediated signaling pathway	IEP	Neighborhood
BP	GO:0010228	vegetative to reproductive phase transition of meristem	IEP	Neighborhood
BP	GO:0010564	regulation of cell cycle process	IEP	Neighborhood
BP	GO:0015031	protein transport	IEP	Neighborhood
BP	GO:0015833	peptide transport	IEP	Neighborhood
BP	GO:0015931	nucleobase-containing compound transport	IEP	Neighborhood
CC	GO:0015935	small ribosomal subunit	IEP	Neighborhood
BP	GO:0016043	cellular component organization	IEP	Neighborhood
BP	GO:0016070	RNA metabolic process	IEP	Neighborhood
MF	GO:0016289	CoA hydrolase activity	IEP	Neighborhood
BP	GO:0016567	protein ubiquitination	IEP	Neighborhood
BP	GO:0016569	covalent chromatin modification	IEP	Neighborhood
BP	GO:0016570	histone modification	IEP	Neighborhood
BP	GO:0016571	histone methylation	IEP	Neighborhood
BP	GO:0016579	protein deubiquitination	IEP	Neighborhood
CC	GO:0016604	nuclear body	IEP	Neighborhood
CC	GO:0016607	nuclear speck	IEP	Neighborhood
MF	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	IEP	Neighborhood
MF	GO:0016886	ligase activity, forming phosphoric ester bonds	IEP	Neighborhood
BP	GO:0017004	cytochrome complex assembly	IEP	Neighborhood
BP	GO:0017038	protein import	IEP	Neighborhood
CC	GO:0017053	transcriptional repressor complex	IEP	Neighborhood
BP	GO:0017126	nucleologenesis	IEP	Neighborhood
BP	GO:0018022	peptidyl-lysine methylation	IEP	Neighborhood
BP	GO:0018193	peptidyl-amino acid modification	IEP	Neighborhood
BP	GO:0018205	peptidyl-lysine modification	IEP	Neighborhood
BP	GO:0019538	protein metabolic process	IEP	Neighborhood
CC	GO:0019866	organelle inner membrane	IEP	Neighborhood
BP	GO:0019915	lipid storage	IEP	Neighborhood
BP	GO:0022402	cell cycle process	IEP	Neighborhood
BP	GO:0022412	cellular process involved in reproduction in multicellular organism	IEP	Neighborhood
BP	GO:0022414	reproductive process	IEP	Neighborhood
BP	GO:0022611	dormancy process	IEP	Neighborhood
BP	GO:0022613	ribonucleoprotein complex biogenesis	IEP	Neighborhood
CC	GO:0022627	cytosolic small ribosomal subunit	IEP	Neighborhood
BP	GO:0030154	cell differentiation	IEP	Neighborhood
BP	GO:0031056	regulation of histone modification	IEP	Neighborhood
BP	GO:0031058	positive regulation of histone modification	IEP	Neighborhood
BP	GO:0031060	regulation of histone methylation	IEP	Neighborhood
BP	GO:0031062	positive regulation of histone methylation	IEP	Neighborhood
BP	GO:0031401	positive regulation of protein modification process	IEP	Neighborhood
CC	GO:0031966	mitochondrial membrane	IEP	Neighborhood
BP	GO:0032259	methylation	IEP	Neighborhood
BP	GO:0032268	regulation of cellular protein metabolic process	IEP	Neighborhood
BP	GO:0032446	protein modification by small protein conjugation	IEP	Neighborhood
BP	GO:0032502	developmental process	IEP	Neighborhood
BP	GO:0033036	macromolecule localization	IEP	Neighborhood
BP	GO:0033043	regulation of organelle organization	IEP	Neighborhood
BP	GO:0033044	regulation of chromosome organization	IEP	Neighborhood
BP	GO:0033365	protein localization to organelle	IEP	Neighborhood
BP	GO:0034504	protein localization to nucleus	IEP	Neighborhood
BP	GO:0034613	cellular protein localization	IEP	Neighborhood
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Neighborhood
BP	GO:0034968	histone lysine methylation	IEP	Neighborhood
BP	GO:0035825	homologous recombination	IEP	Neighborhood
BP	GO:0036211	protein modification process	IEP	Neighborhood
BP	GO:0036260	RNA capping	IEP	Neighborhood
MF	GO:0042083	5,10-methylenetetrahydrofolate-dependent methyltransferase activity	IEP	Neighborhood
BP	GO:0042138	meiotic DNA double-strand break formation	IEP	Neighborhood
BP	GO:0042254	ribosome biogenesis	IEP	Neighborhood
BP	GO:0042559	pteridine-containing compound biosynthetic process	IEP	Neighborhood
BP	GO:0042886	amide transport	IEP	Neighborhood
BP	GO:0042991	obsolete transcription factor import into nucleus	IEP	Neighborhood
BP	GO:0043043	peptide biosynthetic process	IEP	Neighborhood
BP	GO:0043170	macromolecule metabolic process	IEP	Neighborhood
CC	GO:0043226	organelle	IEP	Neighborhood
CC	GO:0043227	membrane-bounded organelle	IEP	Neighborhood
CC	GO:0043228	non-membrane-bounded organelle	IEP	Neighborhood
CC	GO:0043229	intracellular organelle	IEP	Neighborhood
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Neighborhood
CC	GO:0043232	intracellular non-membrane-bounded organelle	IEP	Neighborhood
BP	GO:0043412	macromolecule modification	IEP	Neighborhood
BP	GO:0043414	macromolecule methylation	IEP	Neighborhood
BP	GO:0043603	cellular amide metabolic process	IEP	Neighborhood
BP	GO:0043604	amide biosynthetic process	IEP	Neighborhood
BP	GO:0043650	dicarboxylic acid biosynthetic process	IEP	Neighborhood
BP	GO:0044085	cellular component biogenesis	IEP	Neighborhood
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Neighborhood
BP	GO:0044267	cellular protein metabolic process	IEP	Neighborhood
CC	GO:0044391	ribosomal subunit	IEP	Neighborhood
CC	GO:0044428	nuclear part	IEP	Neighborhood
CC	GO:0044429	mitochondrial part	IEP	Neighborhood
CC	GO:0044451	nucleoplasm part	IEP	Neighborhood
BP	GO:0045132	meiotic chromosome segregation	IEP	Neighborhood
BP	GO:0045184	establishment of protein localization	IEP	Neighborhood
BP	GO:0046653	tetrahydrofolate metabolic process	IEP	Neighborhood
BP	GO:0046654	tetrahydrofolate biosynthetic process	IEP	Neighborhood
BP	GO:0046907	intracellular transport	IEP	Neighborhood
BP	GO:0048284	organelle fusion	IEP	Neighborhood
BP	GO:0048366	leaf development	IEP	Neighborhood
BP	GO:0048532	anatomical structure arrangement	IEP	Neighborhood
BP	GO:0048572	short-day photoperiodism	IEP	Neighborhood
BP	GO:0048575	short-day photoperiodism, flowering	IEP	Neighborhood
BP	GO:0048580	regulation of post-embryonic development	IEP	Neighborhood
BP	GO:0048609	multicellular organismal reproductive process	IEP	Neighborhood
BP	GO:0048825	cotyledon development	IEP	Neighborhood
BP	GO:0048831	regulation of shoot system development	IEP	Neighborhood
BP	GO:0048869	cellular developmental process	IEP	Neighborhood
BP	GO:0050657	nucleic acid transport	IEP	Neighborhood
BP	GO:0050658	RNA transport	IEP	Neighborhood
BP	GO:0050793	regulation of developmental process	IEP	Neighborhood
BP	GO:0050826	response to freezing	IEP	Neighborhood
BP	GO:0051028	mRNA transport	IEP	Neighborhood
BP	GO:0051168	nuclear export	IEP	Neighborhood
BP	GO:0051169	nuclear transport	IEP	Neighborhood
BP	GO:0051170	import into nucleus	IEP	Neighborhood
BP	GO:0051179	localization	IEP	Neighborhood
BP	GO:0051234	establishment of localization	IEP	Neighborhood
BP	GO:0051235	maintenance of location	IEP	Neighborhood
BP	GO:0051236	establishment of RNA localization	IEP	Neighborhood
BP	GO:0051239	regulation of multicellular organismal process	IEP	Neighborhood
BP	GO:0051246	regulation of protein metabolic process	IEP	Neighborhood
BP	GO:0051276	chromosome organization	IEP	Neighborhood
BP	GO:0051301	cell division	IEP	Neighborhood
BP	GO:0051569	regulation of histone H3-K4 methylation	IEP	Neighborhood
BP	GO:0051571	positive regulation of histone H3-K4 methylation	IEP	Neighborhood
BP	GO:0051604	protein maturation	IEP	Neighborhood
BP	GO:0051641	cellular localization	IEP	Neighborhood
BP	GO:0051649	establishment of localization in cell	IEP	Neighborhood
BP	GO:0051726	regulation of cell cycle	IEP	Neighborhood
BP	GO:0061085	regulation of histone H3-K27 methylation	IEP	Neighborhood
BP	GO:0061087	positive regulation of histone H3-K27 methylation	IEP	Neighborhood
BP	GO:0061982	meiosis I cell cycle process	IEP	Neighborhood
BP	GO:0070192	chromosome organization involved in meiotic cell cycle	IEP	Neighborhood
MF	GO:0070568	guanylyltransferase activity	IEP	Neighborhood
BP	GO:0070585	protein localization to mitochondrion	IEP	Neighborhood
BP	GO:0070646	protein modification by small protein removal	IEP	Neighborhood
BP	GO:0070647	protein modification by small protein conjugation or removal	IEP	Neighborhood
BP	GO:0070727	cellular macromolecule localization	IEP	Neighborhood
BP	GO:0071702	organic substance transport	IEP	Neighborhood
BP	GO:0071705	nitrogen compound transport	IEP	Neighborhood
BP	GO:0071840	cellular component organization or biogenesis	IEP	Neighborhood
BP	GO:0072594	establishment of protein localization to organelle	IEP	Neighborhood
BP	GO:0072655	establishment of protein localization to mitochondrion	IEP	Neighborhood
BP	GO:0080156	mitochondrial mRNA modification	IEP	Neighborhood
BP	GO:0090304	nucleic acid metabolic process	IEP	Neighborhood
BP	GO:0090305	nucleic acid phosphodiester bond hydrolysis	IEP	Neighborhood
CC	GO:0090568	nuclear transcriptional repressor complex	IEP	Neighborhood
BP	GO:0098781	ncRNA transcription	IEP	Neighborhood
BP	GO:0098813	nuclear chromosome segregation	IEP	Neighborhood
BP	GO:1900864	mitochondrial RNA modification	IEP	Neighborhood
BP	GO:1902275	regulation of chromatin organization	IEP	Neighborhood
BP	GO:1903046	meiotic cell cycle process	IEP	Neighborhood
BP	GO:1905269	positive regulation of chromatin organization	IEP	Neighborhood
CC	GO:1990904	ribonucleoprotein complex	IEP	Neighborhood
BP	GO:2000026	regulation of multicellular organismal development	IEP	Neighborhood
BP	GO:2000241	regulation of reproductive process	IEP	Neighborhood
BP	GO:2001252	positive regulation of chromosome organization	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR011488	TIF_2_asu	130	258
IPR003029	S1_domain	27	92

External Links

No external refs found!

AT5G05470 (ATEIF2-A2, EIF2-A2, EIF2 ALPHA)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation