MA_10427871g0010

Description : component MLH1 of MLH1-PMS1 heterodimer

Gene families : OG0005285 (Archaeplastida) Phylogenetic Tree(s): OG0005285_tree ,
OG_05_0007792 (LandPlants) Phylogenetic Tree(s): OG_05_0007792_tree ,
OG_06_0008410 (SeedPlants) Phylogenetic Tree(s): OG_06_0008410_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: MA_10427871g0010
Cluster	HCCA: Cluster_401

Target	Alias	Description	ECC score	Gene Family Method
Cre01.g036050	No alias	DNA damage response.DNA repair mechanisms.mismatch...	0.02	Archaeplastida
LOC_Os01g72880.1	No alias	component MLH1 of MLH1-PMS1 heterodimer	0.03	Archaeplastida
MA_10425989g0010	No alias	DNA mismatch repair protein MLH1 OS=Arabidopsis thaliana...	0.05	Archaeplastida
Mp5g08620.1	No alias	component MLH1 of MLH1-PMS1 heterodimer	0.02	Archaeplastida

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003678	DNA helicase activity	IEP	Neighborhood
MF	GO:0003909	DNA ligase activity	IEP	Neighborhood
MF	GO:0003910	DNA ligase (ATP) activity	IEP	Neighborhood
MF	GO:0004386	helicase activity	IEP	Neighborhood
CC	GO:0005634	nucleus	IEP	Neighborhood
BP	GO:0006310	DNA recombination	IEP	Neighborhood
BP	GO:0006325	chromatin organization	IEP	Neighborhood
BP	GO:0006464	cellular protein modification process	IEP	Neighborhood
BP	GO:0006479	protein methylation	IEP	Neighborhood
BP	GO:0006508	proteolysis	IEP	Neighborhood
MF	GO:0008168	methyltransferase activity	IEP	Neighborhood
MF	GO:0008170	N-methyltransferase activity	IEP	Neighborhood
BP	GO:0008213	protein alkylation	IEP	Neighborhood
MF	GO:0008233	peptidase activity	IEP	Neighborhood
MF	GO:0008234	cysteine-type peptidase activity	IEP	Neighborhood
MF	GO:0008276	protein methyltransferase activity	IEP	Neighborhood
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	IEP	Neighborhood
BP	GO:0016043	cellular component organization	IEP	Neighborhood
MF	GO:0016278	lysine N-methyltransferase activity	IEP	Neighborhood
MF	GO:0016279	protein-lysine N-methyltransferase activity	IEP	Neighborhood
BP	GO:0016569	covalent chromatin modification	IEP	Neighborhood
BP	GO:0016570	histone modification	IEP	Neighborhood
BP	GO:0016571	histone methylation	IEP	Neighborhood
BP	GO:0016579	protein deubiquitination	IEP	Neighborhood
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Neighborhood
MF	GO:0016787	hydrolase activity	IEP	Neighborhood
MF	GO:0016886	ligase activity, forming phosphoric ester bonds	IEP	Neighborhood
BP	GO:0018022	peptidyl-lysine methylation	IEP	Neighborhood
MF	GO:0018024	histone-lysine N-methyltransferase activity	IEP	Neighborhood
BP	GO:0018193	peptidyl-amino acid modification	IEP	Neighborhood
BP	GO:0018205	peptidyl-lysine modification	IEP	Neighborhood
MF	GO:0019783	ubiquitin-like protein-specific protease activity	IEP	Neighborhood
BP	GO:0032259	methylation	IEP	Neighborhood
BP	GO:0034968	histone lysine methylation	IEP	Neighborhood
BP	GO:0036211	protein modification process	IEP	Neighborhood
MF	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	IEP	Neighborhood
MF	GO:0042054	histone methyltransferase activity	IEP	Neighborhood
CC	GO:0043227	membrane-bounded organelle	IEP	Neighborhood
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Neighborhood
BP	GO:0043412	macromolecule modification	IEP	Neighborhood
BP	GO:0043414	macromolecule methylation	IEP	Neighborhood
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Neighborhood
BP	GO:0070646	protein modification by small protein removal	IEP	Neighborhood
BP	GO:0070647	protein modification by small protein conjugation or removal	IEP	Neighborhood
BP	GO:0071840	cellular component organization or biogenesis	IEP	Neighborhood
MF	GO:0101005	ubiquitinyl hydrolase activity	IEP	Neighborhood
MF	GO:0140096	catalytic activity, acting on a protein	IEP	Neighborhood
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR013507	DNA_mismatch_S5_2-like	227	348

External Links

No external refs found!

MA_10427871g0010

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation