MA_59360g0010

Description : component MSH2 of MSH2-x mismatch repair heterodimers

Gene families : OG0004906 (Archaeplastida) Phylogenetic Tree(s): OG0004906_tree ,
OG_05_0005790 (LandPlants) Phylogenetic Tree(s): OG_05_0005790_tree ,
OG_06_0010054 (SeedPlants) Phylogenetic Tree(s): OG_06_0010054_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: MA_59360g0010
Cluster	HCCA: Cluster_194

Target	Alias	Description	ECC score	Gene Family Method
AMTR_s00007p00236950	evm_27.TU.AmTr_v1...	DNA damage response.DNA repair mechanisms.mismatch...	0.12	Archaeplastida
AT3G18524	ATMSH2, MSH2	MUTS homolog 2	0.12	Archaeplastida
Cpa\|evm.model.tig00001224.8	No alias	DNA damage response.DNA repair mechanisms.mismatch...	0.06	Archaeplastida
Cre01.g003463	No alias	DNA mismatch repair protein MSH2 OS=Zea mays	0.1	Archaeplastida
GSVIVT01008235001	No alias	DNA damage response.DNA repair mechanisms.mismatch...	0.02	Archaeplastida
Gb_33909	No alias	component MSH2 of MSH2-x mismatch repair heterodimers	0.09	Archaeplastida
Mp4g08420.1	No alias	component MSH2 of MSH2-x mismatch repair heterodimers	0.08	Archaeplastida
Pp3c22_850V3.1	No alias	MUTS homolog 2	0.07	Archaeplastida
Solyc06g069230.3.1	No alias	component MSH2 of MSH2-x mismatch repair heterodimers	0.05	Archaeplastida
Zm00001e035455_P001	No alias	component MSH2 of MSH2-x mismatch repair heterodimers	0.05	Archaeplastida

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003678	DNA helicase activity	IEP	Neighborhood
MF	GO:0003682	chromatin binding	IEP	Neighborhood
MF	GO:0003774	motor activity	IEP	Neighborhood
MF	GO:0003777	microtubule motor activity	IEP	Neighborhood
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Neighborhood
MF	GO:0003950	NAD+ ADP-ribosyltransferase activity	IEP	Neighborhood
MF	GO:0004386	helicase activity	IEP	Neighborhood
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Neighborhood
MF	GO:0005515	protein binding	IEP	Neighborhood
CC	GO:0005634	nucleus	IEP	Neighborhood
CC	GO:0005694	chromosome	IEP	Neighborhood
BP	GO:0006260	DNA replication	IEP	Neighborhood
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Neighborhood
BP	GO:0006275	regulation of DNA replication	IEP	Neighborhood
BP	GO:0006471	protein ADP-ribosylation	IEP	Neighborhood
BP	GO:0006928	movement of cell or subcellular component	IEP	Neighborhood
BP	GO:0006996	organelle organization	IEP	Neighborhood
BP	GO:0007017	microtubule-based process	IEP	Neighborhood
BP	GO:0007018	microtubule-based movement	IEP	Neighborhood
MF	GO:0008017	microtubule binding	IEP	Neighborhood
MF	GO:0008092	cytoskeletal protein binding	IEP	Neighborhood
BP	GO:0008156	negative regulation of DNA replication	IEP	Neighborhood
MF	GO:0008270	zinc ion binding	IEP	Neighborhood
BP	GO:0009058	biosynthetic process	IEP	Neighborhood
BP	GO:0009059	macromolecule biosynthetic process	IEP	Neighborhood
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Neighborhood
BP	GO:0009892	negative regulation of metabolic process	IEP	Neighborhood
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Neighborhood
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	Neighborhood
MF	GO:0015631	tubulin binding	IEP	Neighborhood
BP	GO:0016043	cellular component organization	IEP	Neighborhood
MF	GO:0016462	pyrophosphatase activity	IEP	Neighborhood
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Neighborhood
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Neighborhood
MF	GO:0016763	transferase activity, transferring pentosyl groups	IEP	Neighborhood
MF	GO:0016779	nucleotidyltransferase activity	IEP	Neighborhood
MF	GO:0016787	hydrolase activity	IEP	Neighborhood
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Neighborhood
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Neighborhood
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Neighborhood
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Neighborhood
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Neighborhood
BP	GO:0032774	RNA biosynthetic process	IEP	Neighborhood
MF	GO:0034061	DNA polymerase activity	IEP	Neighborhood
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Neighborhood
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Neighborhood
MF	GO:0043138	3'-5' DNA helicase activity	IEP	Neighborhood
CC	GO:0043226	organelle	IEP	Neighborhood
CC	GO:0043227	membrane-bounded organelle	IEP	Neighborhood
CC	GO:0043229	intracellular organelle	IEP	Neighborhood
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Neighborhood
BP	GO:0044249	cellular biosynthetic process	IEP	Neighborhood
CC	GO:0044424	intracellular part	IEP	Neighborhood
CC	GO:0044464	cell part	IEP	Neighborhood
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	IEP	Neighborhood
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Neighborhood
MF	GO:0046914	transition metal ion binding	IEP	Neighborhood
BP	GO:0048478	replication fork protection	IEP	Neighborhood
BP	GO:0048523	negative regulation of cellular process	IEP	Neighborhood
BP	GO:0051052	regulation of DNA metabolic process	IEP	Neighborhood
BP	GO:0051053	negative regulation of DNA metabolic process	IEP	Neighborhood
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Neighborhood
BP	GO:0051276	chromosome organization	IEP	Neighborhood
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Neighborhood
BP	GO:0071840	cellular component organization or biogenesis	IEP	Neighborhood
BP	GO:0090329	regulation of DNA-dependent DNA replication	IEP	Neighborhood
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Neighborhood
BP	GO:1901576	organic substance biosynthetic process	IEP	Neighborhood
BP	GO:2000104	negative regulation of DNA-dependent DNA replication	IEP	Neighborhood
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR007696	DNA_mismatch_repair_MutS_core	213	520
IPR007861	DNA_mismatch_repair_MutS_clamp	382	478
IPR007860	DNA_mmatch_repair_MutS_con_dom	57	194

External Links

No external refs found!

MA_59360g0010

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation