MA_80165g0010

Description : catalytic component POL2/POLE1 of DNA polymerase epsilon complex

Gene families : OG0003279 (Archaeplastida) Phylogenetic Tree(s): OG0003279_tree ,
OG_05_0003575 (LandPlants) Phylogenetic Tree(s): OG_05_0003575_tree ,
OG_06_0002633 (SeedPlants) Phylogenetic Tree(s): OG_06_0002633_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: MA_80165g0010
Cluster	HCCA: Cluster_379

Target	Alias	Description	ECC score	Gene Family Method
AMTR_s00040p00175760	evm_27.TU.AmTr_v1...	Cell cycle.interphase.DNA replication.elongation.DNA...	0.16	Archaeplastida
AMTR_s00040p00177210	evm_27.TU.AmTr_v1...	Cell cycle.interphase.DNA replication.elongation.DNA...	0.15	Archaeplastida
AT1G08260	TIL1, POL2A,...	DNA polymerase epsilon catalytic subunit	0.02	Archaeplastida
Cpa\|evm.model.tig00000970.30	No alias	Cell cycle.interphase.DNA replication.elongation.DNA...	0.04	Archaeplastida
Cpa\|evm.model.tig00000970.31	No alias	DNA polymerase epsilon catalytic subunit A...	0.02	Archaeplastida
Cre03.g179961	No alias	Cell cycle.interphase.DNA replication.elongation.DNA...	0.08	Archaeplastida
GSVIVT01031365001	No alias	Cell cycle.interphase.DNA replication.elongation.DNA...	0.02	Archaeplastida
Gb_06608	No alias	catalytic component POL2/POLE1 of DNA polymerase epsilon complex	0.1	Archaeplastida
LOC_Os02g30800.1	No alias	catalytic component POL2/POLE1 of DNA polymerase epsilon complex	0.1	Archaeplastida
Mp3g08150.1	No alias	catalytic component POL2/POLE1 of DNA polymerase epsilon complex	0.08	Archaeplastida
Smo442263	No alias	Cell cycle.interphase.DNA replication.elongation.DNA...	0.04	Archaeplastida
Solyc11g067140.2.1	No alias	catalytic component POL2/POLE1 of DNA polymerase epsilon complex	0.04	Archaeplastida
Zm00001e014636_P002	No alias	catalytic component POL2/POLE1 of DNA polymerase epsilon complex	0.12	Archaeplastida

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003887	DNA-directed DNA polymerase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006260	DNA replication	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008270	zinc ion binding	IEA	Interproscan
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
MF	GO:0034061	DNA polymerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Neighborhood
CC	GO:0000808	origin recognition complex	IEP	Neighborhood
MF	GO:0003676	nucleic acid binding	IEP	Neighborhood
MF	GO:0003677	DNA binding	IEP	Neighborhood
MF	GO:0003678	DNA helicase activity	IEP	Neighborhood
MF	GO:0003682	chromatin binding	IEP	Neighborhood
MF	GO:0003690	double-stranded DNA binding	IEP	Neighborhood
MF	GO:0003916	DNA topoisomerase activity	IEP	Neighborhood
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEP	Neighborhood
MF	GO:0005524	ATP binding	IEP	Neighborhood
CC	GO:0005664	nuclear origin of replication recognition complex	IEP	Neighborhood
CC	GO:0005694	chromosome	IEP	Neighborhood
BP	GO:0006265	DNA topological change	IEP	Neighborhood
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Neighborhood
BP	GO:0006270	DNA replication initiation	IEP	Neighborhood
BP	GO:0006275	regulation of DNA replication	IEP	Neighborhood
BP	GO:0006281	DNA repair	IEP	Neighborhood
BP	GO:0006298	mismatch repair	IEP	Neighborhood
BP	GO:0006950	response to stress	IEP	Neighborhood
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Neighborhood
BP	GO:0006996	organelle organization	IEP	Neighborhood
MF	GO:0008094	DNA-dependent ATPase activity	IEP	Neighborhood
MF	GO:0008144	drug binding	IEP	Neighborhood
BP	GO:0008156	negative regulation of DNA replication	IEP	Neighborhood
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Neighborhood
BP	GO:0009892	negative regulation of metabolic process	IEP	Neighborhood
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Neighborhood
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	Neighborhood
BP	GO:0016043	cellular component organization	IEP	Neighborhood
MF	GO:0016462	pyrophosphatase activity	IEP	Neighborhood
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Neighborhood
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Neighborhood
MF	GO:0016853	isomerase activity	IEP	Neighborhood
MF	GO:0016887	ATPase activity	IEP	Neighborhood
MF	GO:0017076	purine nucleotide binding	IEP	Neighborhood
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Neighborhood
MF	GO:0030554	adenyl nucleotide binding	IEP	Neighborhood
MF	GO:0030983	mismatched DNA binding	IEP	Neighborhood
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Neighborhood
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Neighborhood
MF	GO:0032553	ribonucleotide binding	IEP	Neighborhood
MF	GO:0032555	purine ribonucleotide binding	IEP	Neighborhood
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Neighborhood
BP	GO:0032774	RNA biosynthetic process	IEP	Neighborhood
BP	GO:0033554	cellular response to stress	IEP	Neighborhood
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Neighborhood
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Neighborhood
MF	GO:0036094	small molecule binding	IEP	Neighborhood
MF	GO:0042623	ATPase activity, coupled	IEP	Neighborhood
MF	GO:0043138	3'-5' DNA helicase activity	IEP	Neighborhood
MF	GO:0043168	anion binding	IEP	Neighborhood
CC	GO:0044454	nuclear chromosome part	IEP	Neighborhood
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	IEP	Neighborhood
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Neighborhood
BP	GO:0048478	replication fork protection	IEP	Neighborhood
BP	GO:0048523	negative regulation of cellular process	IEP	Neighborhood
BP	GO:0050896	response to stimulus	IEP	Neighborhood
BP	GO:0051052	regulation of DNA metabolic process	IEP	Neighborhood
BP	GO:0051053	negative regulation of DNA metabolic process	IEP	Neighborhood
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Neighborhood
BP	GO:0051276	chromosome organization	IEP	Neighborhood
BP	GO:0051716	cellular response to stimulus	IEP	Neighborhood
MF	GO:0061505	DNA topoisomerase II activity	IEP	Neighborhood
BP	GO:0071103	DNA conformation change	IEP	Neighborhood
BP	GO:0071840	cellular component organization or biogenesis	IEP	Neighborhood
BP	GO:0090329	regulation of DNA-dependent DNA replication	IEP	Neighborhood
MF	GO:0097159	organic cyclic compound binding	IEP	Neighborhood
MF	GO:0097367	carbohydrate derivative binding	IEP	Neighborhood
MF	GO:1901265	nucleoside phosphate binding	IEP	Neighborhood
MF	GO:1901363	heterocyclic compound binding	IEP	Neighborhood
BP	GO:2000104	negative regulation of DNA-dependent DNA replication	IEP	Neighborhood
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR013697	DNA_pol_e_suA_C	221	582

External Links

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MA_80165g0010

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation