Solyc05g014740.1.1

Description : DNA topoisomerase 3-alpha OS=Oryza sativa subsp. japonica (sp|c7j0a2|top3a_orysj : 231.0)

Gene families : OG0001504 (Archaeplastida) Phylogenetic Tree(s): OG0001504_tree ,
OG_05_0005827 (LandPlants) Phylogenetic Tree(s): OG_05_0005827_tree ,
OG_06_0006160 (SeedPlants) Phylogenetic Tree(s): OG_06_0006160_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Solyc05g014740.1.1
Cluster	HCCA: Cluster_22

Target	Alias	Description	ECC score	Gene Family Method
GSVIVT01026461001	No alias	DNA topoisomerase 3-alpha OS=Arabidopsis thaliana	0.03	Archaeplastida
MA_18230g0010	No alias	DNA topoisomerase 3-alpha OS=Arabidopsis thaliana...	0.04	Archaeplastida
Zm00001e034601_P002	No alias	topoisomerase component TOP3b of TDRD3-TOP3B...	0.02	Archaeplastida

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000159	protein phosphatase type 2A complex	IEP	Neighborhood
MF	GO:0000166	nucleotide binding	IEP	Neighborhood
BP	GO:0000723	telomere maintenance	IEP	Neighborhood
CC	GO:0000781	chromosome, telomeric region	IEP	Neighborhood
CC	GO:0000784	nuclear chromosome, telomeric region	IEP	Neighborhood
BP	GO:0001510	RNA methylation	IEP	Neighborhood
MF	GO:0003682	chromatin binding	IEP	Neighborhood
MF	GO:0003689	DNA clamp loader activity	IEP	Neighborhood
MF	GO:0003697	single-stranded DNA binding	IEP	Neighborhood
MF	GO:0003774	motor activity	IEP	Neighborhood
MF	GO:0003777	microtubule motor activity	IEP	Neighborhood
MF	GO:0004146	dihydrofolate reductase activity	IEP	Neighborhood
MF	GO:0005515	protein binding	IEP	Neighborhood
MF	GO:0005524	ATP binding	IEP	Neighborhood
CC	GO:0005634	nucleus	IEP	Neighborhood
CC	GO:0005663	DNA replication factor C complex	IEP	Neighborhood
CC	GO:0005667	transcription factor complex	IEP	Neighborhood
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Neighborhood
BP	GO:0006270	DNA replication initiation	IEP	Neighborhood
BP	GO:0006275	regulation of DNA replication	IEP	Neighborhood
BP	GO:0006325	chromatin organization	IEP	Neighborhood
BP	GO:0006338	chromatin remodeling	IEP	Neighborhood
BP	GO:0006479	protein methylation	IEP	Neighborhood
BP	GO:0006575	cellular modified amino acid metabolic process	IEP	Neighborhood
BP	GO:0006760	folic acid-containing compound metabolic process	IEP	Neighborhood
BP	GO:0006928	movement of cell or subcellular component	IEP	Neighborhood
BP	GO:0007017	microtubule-based process	IEP	Neighborhood
BP	GO:0007018	microtubule-based movement	IEP	Neighborhood
MF	GO:0008017	microtubule binding	IEP	Neighborhood
MF	GO:0008092	cytoskeletal protein binding	IEP	Neighborhood
MF	GO:0008094	DNA-dependent ATPase activity	IEP	Neighborhood
MF	GO:0008144	drug binding	IEP	Neighborhood
BP	GO:0008156	negative regulation of DNA replication	IEP	Neighborhood
MF	GO:0008168	methyltransferase activity	IEP	Neighborhood
BP	GO:0008213	protein alkylation	IEP	Neighborhood
CC	GO:0008287	protein serine/threonine phosphatase complex	IEP	Neighborhood
BP	GO:0009396	folic acid-containing compound biosynthetic process	IEP	Neighborhood
BP	GO:0009452	7-methylguanosine RNA capping	IEP	Neighborhood
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Neighborhood
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Neighborhood
MF	GO:0015631	tubulin binding	IEP	Neighborhood
MF	GO:0016462	pyrophosphatase activity	IEP	Neighborhood
BP	GO:0016571	histone methylation	IEP	Neighborhood
MF	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	IEP	Neighborhood
MF	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	IEP	Neighborhood
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Neighborhood
MF	GO:0016787	hydrolase activity	IEP	Neighborhood
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Neighborhood
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Neighborhood
MF	GO:0017076	purine nucleotide binding	IEP	Neighborhood
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Neighborhood
BP	GO:0018022	peptidyl-lysine methylation	IEP	Neighborhood
MF	GO:0019208	phosphatase regulator activity	IEP	Neighborhood
MF	GO:0019888	protein phosphatase regulator activity	IEP	Neighborhood
MF	GO:0030554	adenyl nucleotide binding	IEP	Neighborhood
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Neighborhood
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Neighborhood
MF	GO:0031491	nucleosome binding	IEP	Neighborhood
BP	GO:0032200	telomere organization	IEP	Neighborhood
BP	GO:0032259	methylation	IEP	Neighborhood
MF	GO:0032553	ribonucleotide binding	IEP	Neighborhood
MF	GO:0032555	purine ribonucleotide binding	IEP	Neighborhood
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Neighborhood
MF	GO:0033170	protein-DNA loading ATPase activity	IEP	Neighborhood
CC	GO:0033643	host cell part	IEP	Neighborhood
CC	GO:0033646	host intracellular part	IEP	Neighborhood
CC	GO:0033647	host intracellular organelle	IEP	Neighborhood
CC	GO:0033648	host intracellular membrane-bounded organelle	IEP	Neighborhood
BP	GO:0034968	histone lysine methylation	IEP	Neighborhood
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Neighborhood
MF	GO:0036094	small molecule binding	IEP	Neighborhood
BP	GO:0036260	RNA capping	IEP	Neighborhood
CC	GO:0042025	host cell nucleus	IEP	Neighborhood
MF	GO:0042162	telomeric DNA binding	IEP	Neighborhood
BP	GO:0042398	cellular modified amino acid biosynthetic process	IEP	Neighborhood
BP	GO:0042558	pteridine-containing compound metabolic process	IEP	Neighborhood
BP	GO:0042559	pteridine-containing compound biosynthetic process	IEP	Neighborhood
MF	GO:0043015	gamma-tubulin binding	IEP	Neighborhood
BP	GO:0043044	ATP-dependent chromatin remodeling	IEP	Neighborhood
MF	GO:0043047	single-stranded telomeric DNA binding	IEP	Neighborhood
MF	GO:0043167	ion binding	IEP	Neighborhood
MF	GO:0043168	anion binding	IEP	Neighborhood
CC	GO:0043227	membrane-bounded organelle	IEP	Neighborhood
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Neighborhood
BP	GO:0043414	macromolecule methylation	IEP	Neighborhood
CC	GO:0044217	other organism part	IEP	Neighborhood
CC	GO:0044424	intracellular part	IEP	Neighborhood
CC	GO:0044427	chromosomal part	IEP	Neighborhood
CC	GO:0044454	nuclear chromosome part	IEP	Neighborhood
CC	GO:0044464	cell part	IEP	Neighborhood
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	IEP	Neighborhood
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Neighborhood
BP	GO:0046653	tetrahydrofolate metabolic process	IEP	Neighborhood
BP	GO:0046654	tetrahydrofolate biosynthetic process	IEP	Neighborhood
BP	GO:0048478	replication fork protection	IEP	Neighborhood
BP	GO:0048523	negative regulation of cellular process	IEP	Neighborhood
BP	GO:0051052	regulation of DNA metabolic process	IEP	Neighborhood
BP	GO:0051053	negative regulation of DNA metabolic process	IEP	Neighborhood
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Neighborhood
BP	GO:0060249	anatomical structure homeostasis	IEP	Neighborhood
MF	GO:0061630	ubiquitin protein ligase activity	IEP	Neighborhood
MF	GO:0061659	ubiquitin-like protein ligase activity	IEP	Neighborhood
BP	GO:0090329	regulation of DNA-dependent DNA replication	IEP	Neighborhood
MF	GO:0097367	carbohydrate derivative binding	IEP	Neighborhood
CC	GO:0098687	chromosomal region	IEP	Neighborhood
MF	GO:0098847	sequence-specific single stranded DNA binding	IEP	Neighborhood
MF	GO:1901265	nucleoside phosphate binding	IEP	Neighborhood
CC	GO:1903293	phosphatase complex	IEP	Neighborhood
BP	GO:2000104	negative regulation of DNA-dependent DNA replication	IEP	Neighborhood
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR013497	Topo_IA_cen	105	238

External Links

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Solyc05g014740.1.1

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation