GSVIVT01027985001

Description : DNA damage response.DNA repair mechanisms.mismatch repair (MMR).MLH1-PMS1 heterodimer.PMS1 component

Gene families : OG0004752 (Archaeplastida) Phylogenetic Tree(s): OG0004752_tree ,
OG_05_0004733 (LandPlants) Phylogenetic Tree(s): OG_05_0004733_tree ,
OG_06_0004714 (SeedPlants) Phylogenetic Tree(s): OG_06_0004714_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: GSVIVT01027985001
Cluster	HCCA: Cluster_123

Target	Alias	Description	ECC score	Gene Family Method
AMTR_s00045p00213360	evm_27.TU.AmTr_v1...	DNA damage response.DNA repair mechanisms.mismatch...	0.02	Archaeplastida
AT4G02460	PMS1	DNA mismatch repair protein, putative	0.06	Archaeplastida
Cpa\|evm.model.tig00000057.93	No alias	DNA mismatch repair protein PMS1 OS=Arabidopsis thaliana	0.01	Archaeplastida
Cre04.g227000	No alias	DNA damage response.DNA repair mechanisms.mismatch...	0.04	Archaeplastida
LOC_Os02g37920.1	No alias	component PMS1 of MLH1-PMS1 heterodimer	0.08	Archaeplastida
Solyc09g074990.4.1	No alias	component PMS1 of MLH1-PMS1 heterodimer	0.08	Archaeplastida
Zm00001e022851_P002	No alias	component PMS1 of MLH1-PMS1 heterodimer	0.07	Archaeplastida

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	IEP	Neighborhood
CC	GO:0000152	nuclear ubiquitin ligase complex	IEP	Neighborhood
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Neighborhood
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Neighborhood
BP	GO:0000398	mRNA splicing, via spliceosome	IEP	Neighborhood
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Neighborhood
MF	GO:0003905	alkylbase DNA N-glycosylase activity	IEP	Neighborhood
MF	GO:0003916	DNA topoisomerase activity	IEP	Neighborhood
MF	GO:0003917	DNA topoisomerase type I activity	IEP	Neighborhood
MF	GO:0005515	protein binding	IEP	Neighborhood
CC	GO:0005634	nucleus	IEP	Neighborhood
CC	GO:0005643	nuclear pore	IEP	Neighborhood
CC	GO:0005680	anaphase-promoting complex	IEP	Neighborhood
CC	GO:0005694	chromosome	IEP	Neighborhood
BP	GO:0006265	DNA topological change	IEP	Neighborhood
BP	GO:0006284	base-excision repair	IEP	Neighborhood
MF	GO:0008092	cytoskeletal protein binding	IEP	Neighborhood
BP	GO:0008380	RNA splicing	IEP	Neighborhood
MF	GO:0008725	DNA-3-methyladenine glycosylase activity	IEP	Neighborhood
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Neighborhood
BP	GO:0009892	negative regulation of metabolic process	IEP	Neighborhood
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Neighborhood
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	Neighborhood
BP	GO:0010629	negative regulation of gene expression	IEP	Neighborhood
MF	GO:0015631	tubulin binding	IEP	Neighborhood
MF	GO:0016779	nucleotidyltransferase activity	IEP	Neighborhood
MF	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	IEP	Neighborhood
MF	GO:0019104	DNA N-glycosylase activity	IEP	Neighborhood
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Neighborhood
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Neighborhood
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	Neighborhood
MF	GO:0034061	DNA polymerase activity	IEP	Neighborhood
MF	GO:0043015	gamma-tubulin binding	IEP	Neighborhood
CC	GO:0043226	organelle	IEP	Neighborhood
CC	GO:0043227	membrane-bounded organelle	IEP	Neighborhood
CC	GO:0043229	intracellular organelle	IEP	Neighborhood
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Neighborhood
MF	GO:0043733	DNA-3-methylbase glycosylase activity	IEP	Neighborhood
CC	GO:0044424	intracellular part	IEP	Neighborhood
CC	GO:0044428	nuclear part	IEP	Neighborhood
CC	GO:0044464	cell part	IEP	Neighborhood
BP	GO:0045892	negative regulation of transcription, DNA-templated	IEP	Neighborhood
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Neighborhood
BP	GO:0048523	negative regulation of cellular process	IEP	Neighborhood
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Neighborhood
BP	GO:0051253	negative regulation of RNA metabolic process	IEP	Neighborhood
BP	GO:0071103	DNA conformation change	IEP	Neighborhood
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Neighborhood
BP	GO:1902679	negative regulation of RNA biosynthetic process	IEP	Neighborhood
BP	GO:1903507	negative regulation of nucleic acid-templated transcription	IEP	Neighborhood
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR014790	MutL_C	636	794
IPR013507	DNA_mismatch_S5_2-like	225	343

External Links

No external refs found!

GSVIVT01027985001

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation