AT2G21550

Description : Bifunctional dihydrofolate reductase/thymidylate synthase

Gene families : OG0004412 (Archaeplastida) Phylogenetic Tree(s): OG0004412_tree ,
OG_05_0048184 (LandPlants) Phylogenetic Tree(s): No tree available for this family ,
OG_06_0043059 (SeedPlants) Phylogenetic Tree(s): No tree available for this family

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AT2G21550
Cluster	HCCA: Cluster_212

Target	Alias	Description	ECC score	Gene Family Method	Actions
Mp2g15380.1	No alias	thymidylate synthase. dihydrofolate reductase	0.02	Archaeplastida

Type	GO Term	Name	Evidence	Source
BP	GO:0000041	transition metal ion transport	RCA	Interproscan
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005737	cytoplasm	ISM	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006260	DNA replication	None	Extended
BP	GO:0006261	DNA-dependent DNA replication	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006810	transport	None	Extended
BP	GO:0006811	ion transport	None	Extended
BP	GO:0006812	cation transport	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0022402	cell cycle process	None	Extended
BP	GO:0030001	metal ion transport	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0042023	DNA endoreduplication	RCA	Interproscan
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0044786	cell cycle DNA replication	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001101	response to acid chemical	IEP	Neighborhood
BP	GO:0002237	response to molecule of bacterial origin	IEP	Neighborhood
MF	GO:0004180	carboxypeptidase activity	IEP	Neighborhood
MF	GO:0004185	serine-type carboxypeptidase activity	IEP	Neighborhood
MF	GO:0004675	transmembrane receptor protein serine/threonine kinase activity	IEP	Neighborhood
MF	GO:0004888	transmembrane signaling receptor activity	IEP	Neighborhood
MF	GO:0005216	ion channel activity	IEP	Neighborhood
MF	GO:0005242	inward rectifier potassium channel activity	IEP	Neighborhood
MF	GO:0005244	voltage-gated ion channel activity	IEP	Neighborhood
MF	GO:0005249	voltage-gated potassium channel activity	IEP	Neighborhood
MF	GO:0005261	cation channel activity	IEP	Neighborhood
MF	GO:0005267	potassium channel activity	IEP	Neighborhood
CC	GO:0005886	plasma membrane	IEP	Neighborhood
BP	GO:0006148	inosine catabolic process	IEP	Neighborhood
BP	GO:0006152	purine nucleoside catabolic process	IEP	Neighborhood
BP	GO:0006154	adenosine catabolic process	IEP	Neighborhood
BP	GO:0006694	steroid biosynthetic process	IEP	Neighborhood
BP	GO:0006820	anion transport	IEP	Neighborhood
BP	GO:0006826	iron ion transport	IEP	Neighborhood
BP	GO:0006882	cellular zinc ion homeostasis	IEP	Neighborhood
BP	GO:0006950	response to stress	IEP	Neighborhood
BP	GO:0007154	cell communication	IEP	Neighborhood
MF	GO:0008144	drug binding	IEP	Neighborhood
BP	GO:0008202	steroid metabolic process	IEP	Neighborhood
MF	GO:0008238	exopeptidase activity	IEP	Neighborhood
MF	GO:0008477	purine nucleosidase activity	IEP	Neighborhood
BP	GO:0009164	nucleoside catabolic process	IEP	Neighborhood
BP	GO:0009267	cellular response to starvation	IEP	Neighborhood
BP	GO:0009308	amine metabolic process	IEP	Neighborhood
BP	GO:0009605	response to external stimulus	IEP	Neighborhood
BP	GO:0009624	response to nematode	IEP	Neighborhood
BP	GO:0009690	cytokinin metabolic process	IEP	Neighborhood
BP	GO:0009691	cytokinin biosynthetic process	IEP	Neighborhood
BP	GO:0009698	phenylpropanoid metabolic process	IEP	Neighborhood
BP	GO:0009734	auxin-activated signaling pathway	IEP	Neighborhood
BP	GO:0009812	flavonoid metabolic process	IEP	Neighborhood
BP	GO:0009813	flavonoid biosynthetic process	IEP	Neighborhood
MF	GO:0009815	1-aminocyclopropane-1-carboxylate oxidase activity	IEP	Neighborhood
BP	GO:0009870	defense response signaling pathway, resistance gene-dependent	IEP	Neighborhood
BP	GO:0009991	response to extracellular stimulus	IEP	Neighborhood
BP	GO:0010033	response to organic substance	IEP	Neighborhood
BP	GO:0010035	response to inorganic substance	IEP	Neighborhood
BP	GO:0010053	root epidermal cell differentiation	IEP	Neighborhood
BP	GO:0010106	cellular response to iron ion starvation	IEP	Neighborhood
BP	GO:0010107	potassium ion import	IEP	Neighborhood
BP	GO:0010167	response to nitrate	IEP	Neighborhood
BP	GO:0010232	vascular transport	IEP	Neighborhood
BP	GO:0010233	phloem transport	IEP	Neighborhood
BP	GO:0010345	suberin biosynthetic process	IEP	Neighborhood
BP	GO:0010359	regulation of anion channel activity	IEP	Neighborhood
BP	GO:0010383	cell wall polysaccharide metabolic process	IEP	Neighborhood
BP	GO:0010393	galacturonan metabolic process	IEP	Neighborhood
BP	GO:0010421	hydrogen peroxide-mediated programmed cell death	IEP	Neighborhood
MF	GO:0015077	monovalent inorganic cation transmembrane transporter activity	IEP	Neighborhood
MF	GO:0015079	potassium ion transmembrane transporter activity	IEP	Neighborhood
MF	GO:0015267	channel activity	IEP	Neighborhood
MF	GO:0015276	ligand-gated ion channel activity	IEP	Neighborhood
MF	GO:0015368	calcium:cation antiporter activity	IEP	Neighborhood
MF	GO:0015369	calcium:proton antiporter activity	IEP	Neighborhood
BP	GO:0015698	inorganic anion transport	IEP	Neighborhood
BP	GO:0015706	nitrate transport	IEP	Neighborhood
BP	GO:0016128	phytosteroid metabolic process	IEP	Neighborhood
BP	GO:0016129	phytosteroid biosynthetic process	IEP	Neighborhood
BP	GO:0016131	brassinosteroid metabolic process	IEP	Neighborhood
BP	GO:0016132	brassinosteroid biosynthetic process	IEP	Neighborhood
MF	GO:0016174	NAD(P)H oxidase activity	IEP	Neighborhood
MF	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEP	Neighborhood
MF	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	IEP	Neighborhood
MF	GO:0019199	transmembrane receptor protein kinase activity	IEP	Neighborhood
MF	GO:0019825	oxygen binding	IEP	Neighborhood
BP	GO:0021700	developmental maturation	IEP	Neighborhood
MF	GO:0022803	passive transmembrane transporter activity	IEP	Neighborhood
MF	GO:0022832	voltage-gated channel activity	IEP	Neighborhood
MF	GO:0022834	ligand-gated channel activity	IEP	Neighborhood
MF	GO:0022836	gated channel activity	IEP	Neighborhood
MF	GO:0022838	substrate-specific channel activity	IEP	Neighborhood
MF	GO:0022839	ion gated channel activity	IEP	Neighborhood
MF	GO:0022843	voltage-gated cation channel activity	IEP	Neighborhood
BP	GO:0022898	regulation of transmembrane transporter activity	IEP	Neighborhood
MF	GO:0030551	cyclic nucleotide binding	IEP	Neighborhood
BP	GO:0031667	response to nutrient levels	IEP	Neighborhood
BP	GO:0031668	cellular response to extracellular stimulus	IEP	Neighborhood
BP	GO:0031669	cellular response to nutrient levels	IEP	Neighborhood
BP	GO:0032409	regulation of transporter activity	IEP	Neighborhood
BP	GO:0032412	regulation of ion transmembrane transporter activity	IEP	Neighborhood
BP	GO:0033554	cellular response to stress	IEP	Neighborhood
BP	GO:0034656	nucleobase-containing small molecule catabolic process	IEP	Neighborhood
BP	GO:0034762	regulation of transmembrane transport	IEP	Neighborhood
BP	GO:0034765	regulation of ion transmembrane transport	IEP	Neighborhood
MF	GO:0035252	UDP-xylosyltransferase activity	IEP	Neighborhood
MF	GO:0036094	small molecule binding	IEP	Neighborhood
BP	GO:0036473	cell death in response to oxidative stress	IEP	Neighborhood
BP	GO:0036474	cell death in response to hydrogen peroxide	IEP	Neighborhood
MF	GO:0038023	signaling receptor activity	IEP	Neighborhood
BP	GO:0042221	response to chemical	IEP	Neighborhood
BP	GO:0042278	purine nucleoside metabolic process	IEP	Neighborhood
MF	GO:0042285	xylosyltransferase activity	IEP	Neighborhood
BP	GO:0042454	ribonucleoside catabolic process	IEP	Neighborhood
BP	GO:0042594	response to starvation	IEP	Neighborhood
BP	GO:0044070	regulation of anion transport	IEP	Neighborhood
MF	GO:0045431	flavonol synthase activity	IEP	Neighborhood
BP	GO:0045488	pectin metabolic process	IEP	Neighborhood
BP	GO:0045489	pectin biosynthetic process	IEP	Neighborhood
BP	GO:0046085	adenosine metabolic process	IEP	Neighborhood
BP	GO:0046102	inosine metabolic process	IEP	Neighborhood
BP	GO:0046128	purine ribonucleoside metabolic process	IEP	Neighborhood
BP	GO:0046130	purine ribonucleoside catabolic process	IEP	Neighborhood
MF	GO:0046873	metal ion transmembrane transporter activity	IEP	Neighborhood
MF	GO:0047622	adenosine nucleosidase activity	IEP	Neighborhood
MF	GO:0047724	inosine nucleosidase activity	IEP	Neighborhood
BP	GO:0048437	floral organ development	IEP	Neighborhood
BP	GO:0048443	stamen development	IEP	Neighborhood
BP	GO:0048469	cell maturation	IEP	Neighborhood
BP	GO:0048764	trichoblast maturation	IEP	Neighborhood
BP	GO:0048765	root hair cell differentiation	IEP	Neighborhood
MF	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	IEP	Neighborhood
MF	GO:0050734	hydroxycinnamoyltransferase activity	IEP	Neighborhood
BP	GO:0050896	response to stimulus	IEP	Neighborhood
MF	GO:0051139	metal ion:proton antiporter activity	IEP	Neighborhood
MF	GO:0051213	dioxygenase activity	IEP	Neighborhood
BP	GO:0051716	cellular response to stimulus	IEP	Neighborhood
BP	GO:0052325	cell wall pectin biosynthetic process	IEP	Neighborhood
BP	GO:0052546	cell wall pectin metabolic process	IEP	Neighborhood
MF	GO:0070008	serine-type exopeptidase activity	IEP	Neighborhood
BP	GO:0071496	cellular response to external stimulus	IEP	Neighborhood
BP	GO:0071695	anatomical structure maturation	IEP	Neighborhood
BP	GO:0071705	nitrogen compound transport	IEP	Neighborhood
BP	GO:0071804	cellular potassium ion transport	IEP	Neighborhood
BP	GO:0071805	potassium ion transmembrane transport	IEP	Neighborhood
BP	GO:0072523	purine-containing compound catabolic process	IEP	Neighborhood
MF	GO:0080044	quercetin 7-O-glucosyltransferase activity	IEP	Neighborhood
MF	GO:0080045	quercetin 3'-O-glucosyltransferase activity	IEP	Neighborhood
BP	GO:0090333	regulation of stomatal closure	IEP	Neighborhood
BP	GO:0090627	plant epidermal cell differentiation	IEP	Neighborhood
BP	GO:0097468	programmed cell death in response to reactive oxygen species	IEP	Neighborhood
MF	GO:0099094	ligand-gated cation channel activity	IEP	Neighborhood
BP	GO:0099402	plant organ development	IEP	Neighborhood
BP	GO:1901698	response to nitrogen compound	IEP	Neighborhood
BP	GO:1901700	response to oxygen-containing compound	IEP	Neighborhood
BP	GO:1903959	regulation of anion transmembrane transport	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR001796	DHFR_dom	26	200
IPR023451	Thymidate_synth/dCMP_Mease	238	489

External Links

No external refs found!

AT2G21550

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation