Gb_08645

Description : hydroxymethylpyrimidine phosphate synthase (ThiC)

Gene families : OG0005858 (Archaeplastida) Phylogenetic Tree(s): OG0005858_tree ,
OG_05_0006887 (LandPlants) Phylogenetic Tree(s): OG_05_0006887_tree ,
OG_06_0009330 (SeedPlants) Phylogenetic Tree(s): OG_06_0009330_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Gb_08645
Cluster	HCCA: Cluster_135

Target	Alias	Description	ECC score	Gene Family Method	Actions
AMTR_s00010p00259490	evm_27.TU.AmTr_v1...	Coenzyme metabolism.thiamine pyrophosphate...	0.07	Archaeplastida
Zm00001e005154_P001	No alias	hydroxymethylpyrimidine phosphate synthase (ThiC)	0.04	Archaeplastida

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006766	vitamin metabolic process	None	Extended
BP	GO:0006767	water-soluble vitamin metabolic process	None	Extended
BP	GO:0006772	thiamine metabolic process	None	Extended
BP	GO:0006790	sulfur compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009110	vitamin biosynthetic process	None	Extended
BP	GO:0009228	thiamine biosynthetic process	IEA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0017144	drug metabolic process	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0042364	water-soluble vitamin biosynthetic process	None	Extended
BP	GO:0042723	thiamine-containing compound metabolic process	None	Extended
BP	GO:0042724	thiamine-containing compound biosynthetic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0044272	sulfur compound biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0051536	iron-sulfur cluster binding	IEA	Interproscan
MF	GO:0051540	metal cluster binding	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072527	pyrimidine-containing compound metabolic process	None	Extended
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Neighborhood
BP	GO:0001505	regulation of neurotransmitter levels	IEP	Neighborhood
MF	GO:0001882	nucleoside binding	IEP	Neighborhood
MF	GO:0001883	purine nucleoside binding	IEP	Neighborhood
MF	GO:0003723	RNA binding	IEP	Neighborhood
MF	GO:0003747	translation release factor activity	IEP	Neighborhood
MF	GO:0003824	catalytic activity	IEP	Neighborhood
MF	GO:0003924	GTPase activity	IEP	Neighborhood
MF	GO:0004222	metalloendopeptidase activity	IEP	Neighborhood
MF	GO:0004375	glycine dehydrogenase (decarboxylating) activity	IEP	Neighborhood
MF	GO:0004386	helicase activity	IEP	Neighborhood
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Neighborhood
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Neighborhood
MF	GO:0004817	cysteine-tRNA ligase activity	IEP	Neighborhood
MF	GO:0004852	uroporphyrinogen-III synthase activity	IEP	Neighborhood
MF	GO:0005524	ATP binding	IEP	Neighborhood
MF	GO:0005525	GTP binding	IEP	Neighborhood
BP	GO:0006082	organic acid metabolic process	IEP	Neighborhood
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Neighborhood
BP	GO:0006399	tRNA metabolic process	IEP	Neighborhood
BP	GO:0006415	translational termination	IEP	Neighborhood
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Neighborhood
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Neighborhood
BP	GO:0006423	cysteinyl-tRNA aminoacylation	IEP	Neighborhood
BP	GO:0006520	cellular amino acid metabolic process	IEP	Neighborhood
BP	GO:0006536	glutamate metabolic process	IEP	Neighborhood
BP	GO:0006537	glutamate biosynthetic process	IEP	Neighborhood
BP	GO:0006544	glycine metabolic process	IEP	Neighborhood
BP	GO:0006546	glycine catabolic process	IEP	Neighborhood
BP	GO:0006629	lipid metabolic process	IEP	Neighborhood
BP	GO:0006720	isoprenoid metabolic process	IEP	Neighborhood
BP	GO:0006721	terpenoid metabolic process	IEP	Neighborhood
BP	GO:0006771	riboflavin metabolic process	IEP	Neighborhood
BP	GO:0008033	tRNA processing	IEP	Neighborhood
MF	GO:0008079	translation termination factor activity	IEP	Neighborhood
MF	GO:0008135	translation factor activity, RNA binding	IEP	Neighborhood
MF	GO:0008144	drug binding	IEP	Neighborhood
MF	GO:0008237	metallopeptidase activity	IEP	Neighborhood
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Neighborhood
BP	GO:0008610	lipid biosynthetic process	IEP	Neighborhood
MF	GO:0008686	3,4-dihydroxy-2-butanone-4-phosphate synthase activity	IEP	Neighborhood
BP	GO:0009063	cellular amino acid catabolic process	IEP	Neighborhood
BP	GO:0009064	glutamine family amino acid metabolic process	IEP	Neighborhood
BP	GO:0009069	serine family amino acid metabolic process	IEP	Neighborhood
BP	GO:0009071	serine family amino acid catabolic process	IEP	Neighborhood
BP	GO:0009084	glutamine family amino acid biosynthetic process	IEP	Neighborhood
BP	GO:0009116	nucleoside metabolic process	IEP	Neighborhood
BP	GO:0009119	ribonucleoside metabolic process	IEP	Neighborhood
BP	GO:0009231	riboflavin biosynthetic process	IEP	Neighborhood
MF	GO:0015930	glutamate synthase activity	IEP	Neighborhood
BP	GO:0015969	guanosine tetraphosphate metabolic process	IEP	Neighborhood
BP	GO:0016054	organic acid catabolic process	IEP	Neighborhood
BP	GO:0016070	RNA metabolic process	IEP	Neighborhood
BP	GO:0016114	terpenoid biosynthetic process	IEP	Neighborhood
MF	GO:0016462	pyrophosphatase activity	IEP	Neighborhood
MF	GO:0016491	oxidoreductase activity	IEP	Neighborhood
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	IEP	Neighborhood
MF	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	IEP	Neighborhood
MF	GO:0016642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	IEP	Neighborhood
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Neighborhood
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Neighborhood
MF	GO:0016787	hydrolase activity	IEP	Neighborhood
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Neighborhood
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Neighborhood
MF	GO:0016829	lyase activity	IEP	Neighborhood
MF	GO:0016836	hydro-lyase activity	IEP	Neighborhood
MF	GO:0016874	ligase activity	IEP	Neighborhood
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Neighborhood
BP	GO:0017038	protein import	IEP	Neighborhood
MF	GO:0017076	purine nucleotide binding	IEP	Neighborhood
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Neighborhood
MF	GO:0017150	tRNA dihydrouridine synthase activity	IEP	Neighborhood
MF	GO:0019001	guanyl nucleotide binding	IEP	Neighborhood
BP	GO:0019752	carboxylic acid metabolic process	IEP	Neighborhood
BP	GO:0022411	cellular component disassembly	IEP	Neighborhood
MF	GO:0030554	adenyl nucleotide binding	IEP	Neighborhood
MF	GO:0032549	ribonucleoside binding	IEP	Neighborhood
MF	GO:0032550	purine ribonucleoside binding	IEP	Neighborhood
MF	GO:0032553	ribonucleotide binding	IEP	Neighborhood
MF	GO:0032555	purine ribonucleotide binding	IEP	Neighborhood
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Neighborhood
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Neighborhood
BP	GO:0032984	protein-containing complex disassembly	IEP	Neighborhood
BP	GO:0033013	tetrapyrrole metabolic process	IEP	Neighborhood
BP	GO:0033014	tetrapyrrole biosynthetic process	IEP	Neighborhood
BP	GO:0033865	nucleoside bisphosphate metabolic process	IEP	Neighborhood
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	IEP	Neighborhood
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	IEP	Neighborhood
BP	GO:0034035	purine ribonucleoside bisphosphate metabolic process	IEP	Neighborhood
BP	GO:0034470	ncRNA processing	IEP	Neighborhood
BP	GO:0034660	ncRNA metabolic process	IEP	Neighborhood
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Neighborhood
MF	GO:0036094	small molecule binding	IEP	Neighborhood
BP	GO:0042133	neurotransmitter metabolic process	IEP	Neighborhood
BP	GO:0042135	neurotransmitter catabolic process	IEP	Neighborhood
BP	GO:0042278	purine nucleoside metabolic process	IEP	Neighborhood
BP	GO:0042726	flavin-containing compound metabolic process	IEP	Neighborhood
BP	GO:0042727	flavin-containing compound biosynthetic process	IEP	Neighborhood
BP	GO:0042737	drug catabolic process	IEP	Neighborhood
BP	GO:0043038	amino acid activation	IEP	Neighborhood
BP	GO:0043039	tRNA aminoacylation	IEP	Neighborhood
MF	GO:0043167	ion binding	IEP	Neighborhood
MF	GO:0043168	anion binding	IEP	Neighborhood
BP	GO:0043436	oxoacid metabolic process	IEP	Neighborhood
BP	GO:0043624	cellular protein complex disassembly	IEP	Neighborhood
BP	GO:0043648	dicarboxylic acid metabolic process	IEP	Neighborhood
BP	GO:0043650	dicarboxylic acid biosynthetic process	IEP	Neighborhood
BP	GO:0044238	primary metabolic process	IEP	Neighborhood
BP	GO:0044255	cellular lipid metabolic process	IEP	Neighborhood
BP	GO:0044282	small molecule catabolic process	IEP	Neighborhood
BP	GO:0046128	purine ribonucleoside metabolic process	IEP	Neighborhood
BP	GO:0046395	carboxylic acid catabolic process	IEP	Neighborhood
MF	GO:0046429	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity	IEP	Neighborhood
MF	GO:0052592	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor	IEP	Neighborhood
BP	GO:0055114	oxidation-reduction process	IEP	Neighborhood
BP	GO:0065008	regulation of biological quality	IEP	Neighborhood
BP	GO:0090304	nucleic acid metabolic process	IEP	Neighborhood
MF	GO:0097159	organic cyclic compound binding	IEP	Neighborhood
MF	GO:0097367	carbohydrate derivative binding	IEP	Neighborhood
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Neighborhood
MF	GO:0140101	catalytic activity, acting on a tRNA	IEP	Neighborhood
BP	GO:1901068	guanosine-containing compound metabolic process	IEP	Neighborhood
MF	GO:1901265	nucleoside phosphate binding	IEP	Neighborhood
MF	GO:1901363	heterocyclic compound binding	IEP	Neighborhood
BP	GO:1901565	organonitrogen compound catabolic process	IEP	Neighborhood
BP	GO:1901605	alpha-amino acid metabolic process	IEP	Neighborhood
BP	GO:1901606	alpha-amino acid catabolic process	IEP	Neighborhood
BP	GO:1901657	glycosyl compound metabolic process	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR002817	ThiC/BzaA/B	175	595

External Links

No external refs found!

Gb_08645

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation