GO:0000165: MAPK cascade (Biological process)

"An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell." [GOC:bf, GOC:mtg_signaling_feb11, PMID:20811974, PMID:9561267]


There are 1568 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_121 Arabidopsis thaliana 18.1 % 0.0 0.0
Cluster_209 Arabidopsis thaliana 7.55 % 0.000658 0.008102
Cluster_169 Arabidopsis thaliana 5.1 % 0.000846 0.004063
Cluster_98 Arabidopsis thaliana 4.95 % 1e-05 2.8e-05
Cluster_126 Arabidopsis thaliana 6.45 % 7.1e-05 0.000417
Cluster_151 Arabidopsis thaliana 6.78 % 0.000988 0.003363
Cluster_177 Arabidopsis thaliana 5.0 % 0.010208 0.037851
Cluster_237 Arabidopsis thaliana 12.0 % 2e-06 4.9e-05
Cluster_142 Arabidopsis thaliana 5.36 % 0.00845 0.043902
Cluster_81 Arabidopsis thaliana 3.6 % 0.009639 0.047923
Cluster_94 Arabidopsis thaliana 11.66 % 0.0 0.0
Cluster_69 Arabidopsis thaliana 5.26 % 0.002524 0.012484
Cluster_140 Arabidopsis thaliana 4.67 % 0.001256 0.015576
Cluster_146 Arabidopsis thaliana 5.41 % 0.000188 0.00188
Cluster_46 Arabidopsis thaliana 8.22 % 1.8e-05 0.00021
Cluster_120 Arabidopsis thaliana 8.74 % 0.0 1e-06
Cluster_243 Arabidopsis thaliana 9.8 % 3.9e-05 0.002025
Cluster_246 Arabidopsis thaliana 5.04 % 0.000274 0.002499
Sequences (1568) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms