Mp2g11510.1

Description : component MRE11 of MRE11-RAD50-NBS1 (MRN) complex. component MRE11 of DNA resection MRE11-RAD50-NBS1 (MRN) complex

Gene families : OG0004492 (Archaeplastida) Phylogenetic Tree(s): OG0004492_tree ,
OG_05_0005063 (LandPlants) Phylogenetic Tree(s): OG_05_0005063_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Mp2g11510.1
Cluster	HCCA: Cluster_149

Target	Alias	Description	ECC score	Gene Family Method
GSVIVT01014441001	No alias	DNA damage response.DNA repair mechanisms.homologous...	0.03	Archaeplastida
Gb_07107	No alias	Double-strand break repair protein MRE11 OS=Oryza sativa...	0.02	Archaeplastida
Gb_09498	No alias	Double-strand break repair protein MRE11 OS=Arabidopsis...	0.03	Archaeplastida

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004519	endonuclease activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006302	double-strand break repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	IEA	Interproscan
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0030145	manganese ion binding	IEA	Interproscan
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000075	cell cycle checkpoint	IEP	Neighborhood
MF	GO:0000166	nucleotide binding	IEP	Neighborhood
BP	GO:0000723	telomere maintenance	IEP	Neighborhood
MF	GO:0003676	nucleic acid binding	IEP	Neighborhood
MF	GO:0003677	DNA binding	IEP	Neighborhood
MF	GO:0003690	double-stranded DNA binding	IEP	Neighborhood
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Neighborhood
MF	GO:0005524	ATP binding	IEP	Neighborhood
BP	GO:0006269	DNA replication, synthesis of RNA primer	IEP	Neighborhood
BP	GO:0006270	DNA replication initiation	IEP	Neighborhood
BP	GO:0006298	mismatch repair	IEP	Neighborhood
BP	GO:0006325	chromatin organization	IEP	Neighborhood
BP	GO:0006333	chromatin assembly or disassembly	IEP	Neighborhood
BP	GO:0006397	mRNA processing	IEP	Neighborhood
BP	GO:0007088	regulation of mitotic nuclear division	IEP	Neighborhood
BP	GO:0007093	mitotic cell cycle checkpoint	IEP	Neighborhood
BP	GO:0007094	mitotic spindle assembly checkpoint	IEP	Neighborhood
BP	GO:0007346	regulation of mitotic cell cycle	IEP	Neighborhood
MF	GO:0008144	drug binding	IEP	Neighborhood
BP	GO:0009262	deoxyribonucleotide metabolic process	IEP	Neighborhood
BP	GO:0009263	deoxyribonucleotide biosynthetic process	IEP	Neighborhood
BP	GO:0010564	regulation of cell cycle process	IEP	Neighborhood
BP	GO:0010639	negative regulation of organelle organization	IEP	Neighborhood
BP	GO:0010948	negative regulation of cell cycle process	IEP	Neighborhood
BP	GO:0010965	regulation of mitotic sister chromatid separation	IEP	Neighborhood
BP	GO:0016043	cellular component organization	IEP	Neighborhood
BP	GO:0016070	RNA metabolic process	IEP	Neighborhood
BP	GO:0016071	mRNA metabolic process	IEP	Neighborhood
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Neighborhood
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Neighborhood
MF	GO:0017076	purine nucleotide binding	IEP	Neighborhood
BP	GO:0018130	heterocycle biosynthetic process	IEP	Neighborhood
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Neighborhood
BP	GO:0022402	cell cycle process	IEP	Neighborhood
BP	GO:0030071	regulation of mitotic metaphase/anaphase transition	IEP	Neighborhood
MF	GO:0030554	adenyl nucleotide binding	IEP	Neighborhood
CC	GO:0030915	Smc5-Smc6 complex	IEP	Neighborhood
MF	GO:0030983	mismatched DNA binding	IEP	Neighborhood
BP	GO:0031123	RNA 3'-end processing	IEP	Neighborhood
BP	GO:0031124	mRNA 3'-end processing	IEP	Neighborhood
BP	GO:0031577	spindle checkpoint	IEP	Neighborhood
BP	GO:0032200	telomere organization	IEP	Neighborhood
MF	GO:0032553	ribonucleotide binding	IEP	Neighborhood
MF	GO:0032555	purine ribonucleotide binding	IEP	Neighborhood
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Neighborhood
BP	GO:0032774	RNA biosynthetic process	IEP	Neighborhood
BP	GO:0033043	regulation of organelle organization	IEP	Neighborhood
BP	GO:0033044	regulation of chromosome organization	IEP	Neighborhood
BP	GO:0033045	regulation of sister chromatid segregation	IEP	Neighborhood
BP	GO:0033046	negative regulation of sister chromatid segregation	IEP	Neighborhood
BP	GO:0033047	regulation of mitotic sister chromatid segregation	IEP	Neighborhood
BP	GO:0033048	negative regulation of mitotic sister chromatid segregation	IEP	Neighborhood
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Neighborhood
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Neighborhood
MF	GO:0036094	small molecule binding	IEP	Neighborhood
CC	GO:0042555	MCM complex	IEP	Neighborhood
BP	GO:0043086	negative regulation of catalytic activity	IEP	Neighborhood
MF	GO:0043168	anion binding	IEP	Neighborhood
BP	GO:0044092	negative regulation of molecular function	IEP	Neighborhood
BP	GO:0045786	negative regulation of cell cycle	IEP	Neighborhood
BP	GO:0045839	negative regulation of mitotic nuclear division	IEP	Neighborhood
BP	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	IEP	Neighborhood
BP	GO:0045930	negative regulation of mitotic cell cycle	IEP	Neighborhood
BP	GO:0048519	negative regulation of biological process	IEP	Neighborhood
BP	GO:0048523	negative regulation of cellular process	IEP	Neighborhood
BP	GO:0050790	regulation of catalytic activity	IEP	Neighborhood
BP	GO:0051095	regulation of helicase activity	IEP	Neighborhood
BP	GO:0051097	negative regulation of helicase activity	IEP	Neighborhood
BP	GO:0051128	regulation of cellular component organization	IEP	Neighborhood
BP	GO:0051129	negative regulation of cellular component organization	IEP	Neighborhood
BP	GO:0051336	regulation of hydrolase activity	IEP	Neighborhood
BP	GO:0051346	negative regulation of hydrolase activity	IEP	Neighborhood
BP	GO:0051726	regulation of cell cycle	IEP	Neighborhood
BP	GO:0051783	regulation of nuclear division	IEP	Neighborhood
BP	GO:0051784	negative regulation of nuclear division	IEP	Neighborhood
BP	GO:0051983	regulation of chromosome segregation	IEP	Neighborhood
BP	GO:0051985	negative regulation of chromosome segregation	IEP	Neighborhood
BP	GO:0060249	anatomical structure homeostasis	IEP	Neighborhood
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Neighborhood
BP	GO:0065007	biological regulation	IEP	Neighborhood
BP	GO:0065009	regulation of molecular function	IEP	Neighborhood
BP	GO:0071173	spindle assembly checkpoint	IEP	Neighborhood
BP	GO:0071174	mitotic spindle checkpoint	IEP	Neighborhood
BP	GO:0071840	cellular component organization or biogenesis	IEP	Neighborhood
MF	GO:0097159	organic cyclic compound binding	IEP	Neighborhood
MF	GO:0097367	carbohydrate derivative binding	IEP	Neighborhood
CC	GO:0106068	SUMO ligase complex	IEP	Neighborhood
MF	GO:1901265	nucleoside phosphate binding	IEP	Neighborhood
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Neighborhood
MF	GO:1901363	heterocyclic compound binding	IEP	Neighborhood
BP	GO:1901987	regulation of cell cycle phase transition	IEP	Neighborhood
BP	GO:1901988	negative regulation of cell cycle phase transition	IEP	Neighborhood
BP	GO:1901990	regulation of mitotic cell cycle phase transition	IEP	Neighborhood
BP	GO:1901991	negative regulation of mitotic cell cycle phase transition	IEP	Neighborhood
BP	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	IEP	Neighborhood
BP	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	IEP	Neighborhood
BP	GO:1903047	mitotic cell cycle process	IEP	Neighborhood
BP	GO:1905462	regulation of DNA duplex unwinding	IEP	Neighborhood
BP	GO:1905463	negative regulation of DNA duplex unwinding	IEP	Neighborhood
BP	GO:1905774	regulation of DNA helicase activity	IEP	Neighborhood
BP	GO:1905775	negative regulation of DNA helicase activity	IEP	Neighborhood
BP	GO:1905818	regulation of chromosome separation	IEP	Neighborhood
BP	GO:1905819	negative regulation of chromosome separation	IEP	Neighborhood
BP	GO:2000816	negative regulation of mitotic sister chromatid separation	IEP	Neighborhood
BP	GO:2001251	negative regulation of chromosome organization	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR007281	Mre11_DNA-bd	297	451
IPR004843	Calcineurin-like_PHP_ApaH	8	252

External Links

No external refs found!

Mp2g11510.1

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation