GO:0006270: DNA replication initiation (Biological process)

"The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate." [ISBN:071673706X, ISBN:0815316194, PMID:28209641]


There are 3195 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_58 Arabidopsis thaliana 4.2 % 1e-06 1.6e-05
Cluster_152 Arabidopsis thaliana 5.95 % 2e-06 1.9e-05
Cluster_49 Arabidopsis thaliana 4.55 % 0.00051 0.003637
Cluster_166 Arabidopsis thaliana 2.54 % 0.002728 0.037096
Cluster_262 Arabidopsis thaliana 3.7 % 0.007195 0.041086
Cluster_110 Arabidopsis thaliana 17.27 % 0.0 0.0
Cluster_60 Amborella trichopoda 0.67 % 0.010881 0.026322
Cluster_46 Cyanophora paradoxa 4.1 % 0.0 0.0
Cluster_22 Gingko biloba 4.88 % 0.0 0.0
Cluster_115 Zea mays 2.82 % 0.0 0.0
Cluster_344 Zea mays 4.0 % 7.7e-05 0.002864
Cluster_175 Zea mays 1.27 % 0.020706 0.042707
Cluster_3 Marchantia polymorpha 5.76 % 0.0 0.0
Cluster_121 Physcomitrella patens 0.51 % 0.012041 0.033588
Cluster_86 Physcomitrella patens 1.35 % 0.004555 0.011594
Cluster_169 Picea abies 2.0 % 0.008224 0.027835
Cluster_194 Picea abies 3.15 % 0.0 0.0
Cluster_30 Picea abies 1.54 % 0.010679 0.048056
Cluster_340 Oryza sativa 3.92 % 7.8e-05 0.002494
Cluster_87 Oryza sativa 1.27 % 0.00074 0.003218
Cluster_1 Oryza sativa 3.92 % 7.8e-05 0.007277
Cluster_173 Oryza sativa 3.45 % 0.0 2e-06
Cluster_77 Solanum lycopersicum 2.42 % 0.0 0.0
Cluster_35 Solanum lycopersicum 0.89 % 0.001516 0.010697
Cluster_53 Vitis vinifera 3.65 % 0.0 0.0
Cluster_110 Chlamydomonas reinhardtii 9.8 % 0.0 0.0
Sequences (3195) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms