AT4G18040 (EIF4E, CUM1, AT.EIF4E1, eIF4E1)

Aliases : EIF4E, CUM1, AT.EIF4E1, eIF4E1

Description : eukaryotic translation initiation factor 4E

Gene families : OG0001900 (Archaeplastida) Phylogenetic Tree(s): OG0001900_tree ,
OG_05_0001753 (LandPlants) Phylogenetic Tree(s): OG_05_0001753_tree ,
OG_06_0002228 (SeedPlants) Phylogenetic Tree(s): OG_06_0002228_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AT4G18040
Cluster	HCCA: Cluster_166

Target	Alias	Description	ECC score	Gene Family Method	Actions
LOC_Os01g73880.1	No alias	component eIF4E of eIF4F mRNA unwinding complex	0.03	Archaeplastida
Pp3c2_32310V3.1	No alias	eukaryotic translation initiation factor 4E	0.02	Archaeplastida

Type	GO Term	Name	Evidence	Source
MF	GO:0000339	RNA cap binding	TAS	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003723	RNA binding	ISS	Interproscan
MF	GO:0003743	translation initiation factor activity	ISS	Interproscan
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IPI	Interproscan
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IDA	Interproscan
CC	GO:0005634	nucleus	ISM	Interproscan
CC	GO:0005730	nucleolus	IDA	Interproscan
CC	GO:0005737	cytoplasm	IDA	Interproscan
CC	GO:0005737	cytoplasm	ISS	Interproscan
CC	GO:0005737	cytoplasm	TAS	Interproscan
BP	GO:0006413	translational initiation	ISS	Interproscan
BP	GO:0006413	translational initiation	TAS	Interproscan
BP	GO:0006605	protein targeting	None	Extended
BP	GO:0006626	protein targeting to mitochondrion	RCA	Interproscan
BP	GO:0006810	transport	None	Extended
BP	GO:0006839	mitochondrial transport	None	Extended
BP	GO:0006886	intracellular protein transport	None	Extended
BP	GO:0008104	protein localization	None	Extended
MF	GO:0008135	translation factor activity, RNA binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009605	response to external stimulus	None	Extended
BP	GO:0009607	response to biotic stimulus	None	Extended
BP	GO:0009615	response to virus	IMP	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0015031	protein transport	None	Extended
BP	GO:0015833	peptide transport	None	Extended
BP	GO:0033036	macromolecule localization	None	Extended
BP	GO:0033365	protein localization to organelle	None	Extended
BP	GO:0034613	cellular protein localization	None	Extended
BP	GO:0042886	amide transport	None	Extended
BP	GO:0043207	response to external biotic stimulus	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044428	nuclear part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0045184	establishment of protein localization	None	Extended
BP	GO:0046907	intracellular transport	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0051641	cellular localization	None	Extended
BP	GO:0051649	establishment of localization in cell	None	Extended
BP	GO:0051704	multi-organism process	None	Extended
BP	GO:0051707	response to other organism	None	Extended
BP	GO:0070585	protein localization to mitochondrion	None	Extended
BP	GO:0070727	cellular macromolecule localization	None	Extended
BP	GO:0071702	organic substance transport	None	Extended
BP	GO:0071705	nitrogen compound transport	None	Extended
BP	GO:0072594	establishment of protein localization to organelle	None	Extended
BP	GO:0072655	establishment of protein localization to mitochondrion	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
BP	GO:0000075	cell cycle checkpoint	IEP	Neighborhood
MF	GO:0000150	recombinase activity	IEP	Neighborhood
CC	GO:0000151	ubiquitin ligase complex	IEP	Neighborhood
BP	GO:0000338	protein deneddylation	IEP	Neighborhood
BP	GO:0000469	cleavage involved in rRNA processing	IEP	Neighborhood
BP	GO:0000478	endonucleolytic cleavage involved in rRNA processing	IEP	Neighborhood
BP	GO:0000724	double-strand break repair via homologous recombination	IEP	Neighborhood
BP	GO:0000725	recombinational repair	IEP	Neighborhood
BP	GO:0000919	cell plate assembly	IEP	Neighborhood
BP	GO:0001510	RNA methylation	IEP	Neighborhood
BP	GO:0002252	immune effector process	IEP	Neighborhood
MF	GO:0003684	damaged DNA binding	IEP	Neighborhood
MF	GO:0003697	single-stranded DNA binding	IEP	Neighborhood
MF	GO:0003729	mRNA binding	IEP	Neighborhood
MF	GO:0003735	structural constituent of ribosome	IEP	Neighborhood
MF	GO:0004070	aspartate carbamoyltransferase activity	IEP	Neighborhood
MF	GO:0005198	structural molecule activity	IEP	Neighborhood
CC	GO:0005739	mitochondrion	IEP	Neighborhood
CC	GO:0005759	mitochondrial matrix	IEP	Neighborhood
CC	GO:0005829	cytosol	IEP	Neighborhood
CC	GO:0005839	proteasome core complex	IEP	Neighborhood
CC	GO:0005840	ribosome	IEP	Neighborhood
BP	GO:0006139	nucleobase-containing compound metabolic process	IEP	Neighborhood
BP	GO:0006220	pyrimidine nucleotide metabolic process	IEP	Neighborhood
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	IEP	Neighborhood
BP	GO:0006260	DNA replication	IEP	Neighborhood
BP	GO:0006261	DNA-dependent DNA replication	IEP	Neighborhood
BP	GO:0006281	DNA repair	IEP	Neighborhood
BP	GO:0006302	double-strand break repair	IEP	Neighborhood
BP	GO:0006310	DNA recombination	IEP	Neighborhood
BP	GO:0006412	translation	IEP	Neighborhood
BP	GO:0006414	translational elongation	IEP	Neighborhood
BP	GO:0006464	cellular protein modification process	IEP	Neighborhood
BP	GO:0006479	protein methylation	IEP	Neighborhood
BP	GO:0006518	peptide metabolic process	IEP	Neighborhood
BP	GO:0006725	cellular aromatic compound metabolic process	IEP	Neighborhood
BP	GO:0006753	nucleoside phosphate metabolic process	IEP	Neighborhood
BP	GO:0006793	phosphorus metabolic process	IEP	Neighborhood
BP	GO:0006796	phosphate-containing compound metabolic process	IEP	Neighborhood
BP	GO:0006807	nitrogen compound metabolic process	IEP	Neighborhood
BP	GO:0006950	response to stress	IEP	Neighborhood
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Neighborhood
BP	GO:0007093	mitotic cell cycle checkpoint	IEP	Neighborhood
BP	GO:0007131	reciprocal meiotic recombination	IEP	Neighborhood
BP	GO:0007140	male meiotic nuclear division	IEP	Neighborhood
BP	GO:0007143	female meiotic nuclear division	IEP	Neighborhood
BP	GO:0007275	multicellular organism development	IEP	Neighborhood
MF	GO:0008170	N-methyltransferase activity	IEP	Neighborhood
CC	GO:0008180	COP9 signalosome	IEP	Neighborhood
BP	GO:0008213	protein alkylation	IEP	Neighborhood
MF	GO:0008276	protein methyltransferase activity	IEP	Neighborhood
BP	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine	IEP	Neighborhood
BP	GO:0009058	biosynthetic process	IEP	Neighborhood
BP	GO:0009059	macromolecule biosynthetic process	IEP	Neighborhood
BP	GO:0009117	nucleotide metabolic process	IEP	Neighborhood
BP	GO:0009165	nucleotide biosynthetic process	IEP	Neighborhood
BP	GO:0009218	pyrimidine ribonucleotide metabolic process	IEP	Neighborhood
BP	GO:0009220	pyrimidine ribonucleotide biosynthetic process	IEP	Neighborhood
BP	GO:0009259	ribonucleotide metabolic process	IEP	Neighborhood
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Neighborhood
BP	GO:0009292	genetic transfer	IEP	Neighborhood
BP	GO:0009294	DNA mediated transformation	IEP	Neighborhood
BP	GO:0009451	RNA modification	IEP	Neighborhood
BP	GO:0009560	embryo sac egg cell differentiation	IEP	Neighborhood
BP	GO:0009639	response to red or far red light	IEP	Neighborhood
BP	GO:0009640	photomorphogenesis	IEP	Neighborhood
BP	GO:0009646	response to absence of light	IEP	Neighborhood
BP	GO:0009756	carbohydrate mediated signaling	IEP	Neighborhood
BP	GO:0009791	post-embryonic development	IEP	Neighborhood
BP	GO:0009845	seed germination	IEP	Neighborhood
BP	GO:0009909	regulation of flower development	IEP	Neighborhood
BP	GO:0009920	cell plate formation involved in plant-type cell wall biogenesis	IEP	Neighborhood
BP	GO:0009933	meristem structural organization	IEP	Neighborhood
BP	GO:0010072	primary shoot apical meristem specification	IEP	Neighborhood
BP	GO:0010091	trichome branching	IEP	Neighborhood
BP	GO:0010162	seed dormancy process	IEP	Neighborhood
BP	GO:0010182	sugar mediated signaling pathway	IEP	Neighborhood
BP	GO:0010228	vegetative to reproductive phase transition of meristem	IEP	Neighborhood
BP	GO:0010431	seed maturation	IEP	Neighborhood
BP	GO:0010564	regulation of cell cycle process	IEP	Neighborhood
BP	GO:0016043	cellular component organization	IEP	Neighborhood
BP	GO:0016070	RNA metabolic process	IEP	Neighborhood
MF	GO:0016273	arginine N-methyltransferase activity	IEP	Neighborhood
MF	GO:0016274	protein-arginine N-methyltransferase activity	IEP	Neighborhood
BP	GO:0016444	somatic cell DNA recombination	IEP	Neighborhood
BP	GO:0016567	protein ubiquitination	IEP	Neighborhood
BP	GO:0016571	histone methylation	IEP	Neighborhood
MF	GO:0016597	amino acid binding	IEP	Neighborhood
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Neighborhood
MF	GO:0016743	carboxyl- or carbamoyltransferase activity	IEP	Neighborhood
BP	GO:0018130	heterocycle biosynthetic process	IEP	Neighborhood
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Neighborhood
BP	GO:0019538	protein metabolic process	IEP	Neighborhood
BP	GO:0019637	organophosphate metabolic process	IEP	Neighborhood
BP	GO:0019693	ribose phosphate metabolic process	IEP	Neighborhood
CC	GO:0019898	extrinsic component of membrane	IEP	Neighborhood
BP	GO:0019915	lipid storage	IEP	Neighborhood
BP	GO:0022402	cell cycle process	IEP	Neighborhood
BP	GO:0022412	cellular process involved in reproduction in multicellular organism	IEP	Neighborhood
BP	GO:0022611	dormancy process	IEP	Neighborhood
BP	GO:0022613	ribonucleoprotein complex biogenesis	IEP	Neighborhood
MF	GO:0031406	carboxylic acid binding	IEP	Neighborhood
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	Neighborhood
BP	GO:0031567	mitotic cell size control checkpoint	IEP	Neighborhood
CC	GO:0031974	membrane-enclosed lumen	IEP	Neighborhood
BP	GO:0032259	methylation	IEP	Neighborhood
BP	GO:0032446	protein modification by small protein conjugation	IEP	Neighborhood
BP	GO:0032501	multicellular organismal process	IEP	Neighborhood
BP	GO:0032774	RNA biosynthetic process	IEP	Neighborhood
CC	GO:0032991	protein-containing complex	IEP	Neighborhood
BP	GO:0034641	cellular nitrogen compound metabolic process	IEP	Neighborhood
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Neighborhood
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Neighborhood
BP	GO:0035825	homologous recombination	IEP	Neighborhood
MF	GO:0036094	small molecule binding	IEP	Neighborhood
BP	GO:0036211	protein modification process	IEP	Neighborhood
BP	GO:0042254	ribosome biogenesis	IEP	Neighborhood
BP	GO:0043043	peptide biosynthetic process	IEP	Neighborhood
BP	GO:0043170	macromolecule metabolic process	IEP	Neighborhood
MF	GO:0043177	organic acid binding	IEP	Neighborhood
CC	GO:0043233	organelle lumen	IEP	Neighborhood
BP	GO:0043412	macromolecule modification	IEP	Neighborhood
BP	GO:0043414	macromolecule methylation	IEP	Neighborhood
BP	GO:0043603	cellular amide metabolic process	IEP	Neighborhood
BP	GO:0043604	amide biosynthetic process	IEP	Neighborhood
BP	GO:0044085	cellular component biogenesis	IEP	Neighborhood
BP	GO:0044238	primary metabolic process	IEP	Neighborhood
BP	GO:0044249	cellular biosynthetic process	IEP	Neighborhood
BP	GO:0044260	cellular macromolecule metabolic process	IEP	Neighborhood
BP	GO:0044267	cellular protein metabolic process	IEP	Neighborhood
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Neighborhood
BP	GO:0044281	small molecule metabolic process	IEP	Neighborhood
CC	GO:0044391	ribosomal subunit	IEP	Neighborhood
CC	GO:0044429	mitochondrial part	IEP	Neighborhood
CC	GO:0044444	cytoplasmic part	IEP	Neighborhood
CC	GO:0044445	cytosolic part	IEP	Neighborhood
BP	GO:0044764	multi-organism cellular process	IEP	Neighborhood
BP	GO:0045003	double-strand break repair via synthesis-dependent strand annealing	IEP	Neighborhood
BP	GO:0045930	negative regulation of mitotic cell cycle	IEP	Neighborhood
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Neighborhood
BP	GO:0046483	heterocycle metabolic process	IEP	Neighborhood
BP	GO:0048229	gametophyte development	IEP	Neighborhood
BP	GO:0048366	leaf development	IEP	Neighborhood
BP	GO:0048532	anatomical structure arrangement	IEP	Neighborhood
BP	GO:0048580	regulation of post-embryonic development	IEP	Neighborhood
BP	GO:0048609	multicellular organismal reproductive process	IEP	Neighborhood
BP	GO:0048825	cotyledon development	IEP	Neighborhood
BP	GO:0048831	regulation of shoot system development	IEP	Neighborhood
BP	GO:0048869	cellular developmental process	IEP	Neighborhood
BP	GO:0050826	response to freezing	IEP	Neighborhood
BP	GO:0051235	maintenance of location	IEP	Neighborhood
BP	GO:0051239	regulation of multicellular organismal process	IEP	Neighborhood
BP	GO:0051276	chromosome organization	IEP	Neighborhood
BP	GO:0051301	cell division	IEP	Neighborhood
BP	GO:0051604	protein maturation	IEP	Neighborhood
BP	GO:0051607	defense response to virus	IEP	Neighborhood
BP	GO:0051726	regulation of cell cycle	IEP	Neighborhood
BP	GO:0055086	nucleobase-containing small molecule metabolic process	IEP	Neighborhood
CC	GO:0070013	intracellular organelle lumen	IEP	Neighborhood
BP	GO:0070647	protein modification by small protein conjugation or removal	IEP	Neighborhood
BP	GO:0071704	organic substance metabolic process	IEP	Neighborhood
BP	GO:0071840	cellular component organization or biogenesis	IEP	Neighborhood
BP	GO:0072527	pyrimidine-containing compound metabolic process	IEP	Neighborhood
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	IEP	Neighborhood
CC	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	IEP	Neighborhood
BP	GO:0090304	nucleic acid metabolic process	IEP	Neighborhood
BP	GO:0090407	organophosphate biosynthetic process	IEP	Neighborhood
BP	GO:0090501	RNA phosphodiester bond hydrolysis	IEP	Neighborhood
BP	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	IEP	Neighborhood
BP	GO:0140013	meiotic nuclear division	IEP	Neighborhood
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Neighborhood
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Neighborhood
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Neighborhood
BP	GO:1901360	organic cyclic compound metabolic process	IEP	Neighborhood
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Neighborhood
BP	GO:1901564	organonitrogen compound metabolic process	IEP	Neighborhood
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Neighborhood
BP	GO:1901576	organic substance biosynthetic process	IEP	Neighborhood
CC	GO:1902494	catalytic complex	IEP	Neighborhood
BP	GO:1903046	meiotic cell cycle process	IEP	Neighborhood
BP	GO:1903047	mitotic cell cycle process	IEP	Neighborhood
CC	GO:1990234	transferase complex	IEP	Neighborhood
CC	GO:1990904	ribonucleoprotein complex	IEP	Neighborhood
BP	GO:2000026	regulation of multicellular organismal development	IEP	Neighborhood
BP	GO:2000241	regulation of reproductive process	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR001040	TIF_eIF_4E	61	213

External Links

No external refs found!

AT4G18040 (EIF4E, CUM1, AT.EIF4E1, eIF4E1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation