AT4G21070 (BRCA1, ATBRCA1)

Aliases : BRCA1, ATBRCA1

Description : breast cancer susceptibility1

Gene families : OG0001412 (Archaeplastida) Phylogenetic Tree(s): OG0001412_tree ,
OG_05_0001772 (LandPlants) Phylogenetic Tree(s): OG_05_0001772_tree ,
OG_06_0001623 (SeedPlants) Phylogenetic Tree(s): OG_06_0001623_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AT4G21070
Cluster	HCCA: Cluster_58

Target	Alias	Description	ECC score	Gene Family Method
AMTR_s00092p00067800	evm_27.TU.AmTr_v1...	DNA damage response.BRCA1â€“BARD1 DNA-damage response...	0.02	Archaeplastida
Cre07.g334650	No alias	DNA damage response.BRCA1â€“BARD1 DNA-damage response...	0.02	Archaeplastida
Gb_00493	No alias	component BRCA1\|BARD1 of BRCA1â€“BARD1 DNA-damage...	0.04	Archaeplastida
LOC_Os04g43300.1	No alias	component BRCA1\|BARD1 of BRCA1â€“BARD1 DNA-damage...	0.02	Archaeplastida
MA_12220g0020	No alias	component BRCA1\|BARD1 of BRCA1â€“BARD1 DNA-damage...	0.05	Archaeplastida
Mp1g00070.1	No alias	component BRCA1\|BARD1 of BRCA1â€“BARD1 DNA-damage...	0.04	Archaeplastida
Solyc06g008210.4.1	No alias	component BRCA1\|BARD1 of BRCA1â€“BARD1 DNA-damage...	0.02	Archaeplastida
Zm00001e007590_P001	No alias	component BRCA1\|BARD1 of BRCA1â€“BARD1 DNA-damage...	0.02	Archaeplastida

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004842	ubiquitin-protein transferase activity	IDA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	IMP	Interproscan
BP	GO:0006302	double-strand break repair	RCA	Interproscan
BP	GO:0006310	DNA recombination	IMP	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009314	response to radiation	None	Extended
BP	GO:0009628	response to abiotic stimulus	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010212	response to ionizing radiation	None	Extended
BP	GO:0010332	response to gamma radiation	IEP	Interproscan
BP	GO:0010332	response to gamma radiation	RCA	Interproscan
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0019787	ubiquitin-like protein transferase activity	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
BP	GO:0000018	regulation of DNA recombination	IEP	Neighborhood
BP	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	IEP	Neighborhood
BP	GO:0000226	microtubule cytoskeleton organization	IEP	Neighborhood
BP	GO:0000280	nuclear division	IEP	Neighborhood
CC	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	IEP	Neighborhood
BP	GO:0000723	telomere maintenance	IEP	Neighborhood
BP	GO:0000724	double-strand break repair via homologous recombination	IEP	Neighborhood
BP	GO:0000725	recombinational repair	IEP	Neighborhood
CC	GO:0000798	nuclear cohesin complex	IEP	Neighborhood
BP	GO:0000911	cytokinesis by cell plate formation	IEP	Neighborhood
BP	GO:0001708	cell fate specification	IEP	Neighborhood
BP	GO:0001932	regulation of protein phosphorylation	IEP	Neighborhood
BP	GO:0001933	negative regulation of protein phosphorylation	IEP	Neighborhood
MF	GO:0004386	helicase activity	IEP	Neighborhood
MF	GO:0004672	protein kinase activity	IEP	Neighborhood
MF	GO:0004674	protein serine/threonine kinase activity	IEP	Neighborhood
MF	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	IEP	Neighborhood
MF	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IEP	Neighborhood
MF	GO:0005488	binding	IEP	Neighborhood
MF	GO:0005515	protein binding	IEP	Neighborhood
CC	GO:0005618	cell wall	IEP	Neighborhood
CC	GO:0005634	nucleus	IEP	Neighborhood
BP	GO:0006260	DNA replication	IEP	Neighborhood
BP	GO:0006261	DNA-dependent DNA replication	IEP	Neighborhood
BP	GO:0006346	methylation-dependent chromatin silencing	IEP	Neighborhood
BP	GO:0006469	negative regulation of protein kinase activity	IEP	Neighborhood
BP	GO:0006996	organelle organization	IEP	Neighborhood
BP	GO:0007010	cytoskeleton organization	IEP	Neighborhood
BP	GO:0007017	microtubule-based process	IEP	Neighborhood
BP	GO:0007051	spindle organization	IEP	Neighborhood
BP	GO:0007275	multicellular organism development	IEP	Neighborhood
BP	GO:0007346	regulation of mitotic cell cycle	IEP	Neighborhood
MF	GO:0008026	ATP-dependent helicase activity	IEP	Neighborhood
MF	GO:0008094	DNA-dependent ATPase activity	IEP	Neighborhood
BP	GO:0008219	cell death	IEP	Neighborhood
CC	GO:0008278	cohesin complex	IEP	Neighborhood
BP	GO:0009058	biosynthetic process	IEP	Neighborhood
BP	GO:0009059	macromolecule biosynthetic process	IEP	Neighborhood
BP	GO:0009186	deoxyribonucleoside diphosphate metabolic process	IEP	Neighborhood
BP	GO:0009561	megagametogenesis	IEP	Neighborhood
BP	GO:0009892	negative regulation of metabolic process	IEP	Neighborhood
BP	GO:0010389	regulation of G2/M transition of mitotic cell cycle	IEP	Neighborhood
BP	GO:0010440	stomatal lineage progression	IEP	Neighborhood
BP	GO:0010520	regulation of reciprocal meiotic recombination	IEP	Neighborhood
BP	GO:0010563	negative regulation of phosphorus metabolic process	IEP	Neighborhood
BP	GO:0010564	regulation of cell cycle process	IEP	Neighborhood
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	Neighborhood
BP	GO:0010639	negative regulation of organelle organization	IEP	Neighborhood
BP	GO:0010948	negative regulation of cell cycle process	IEP	Neighborhood
BP	GO:0012501	programmed cell death	IEP	Neighborhood
BP	GO:0016246	RNA interference	IEP	Neighborhood
BP	GO:0016441	posttranscriptional gene silencing	IEP	Neighborhood
MF	GO:0016462	pyrophosphatase activity	IEP	Neighborhood
MF	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	IEP	Neighborhood
BP	GO:0016572	histone phosphorylation	IEP	Neighborhood
MF	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	IEP	Neighborhood
MF	GO:0016728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	IEP	Neighborhood
MF	GO:0016773	phosphotransferase activity, alcohol group as acceptor	IEP	Neighborhood
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Neighborhood
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Neighborhood
MF	GO:0016887	ATPase activity	IEP	Neighborhood
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Neighborhood
MF	GO:0019207	kinase regulator activity	IEP	Neighborhood
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	IEP	Neighborhood
BP	GO:0019222	regulation of metabolic process	IEP	Neighborhood
MF	GO:0019887	protein kinase regulator activity	IEP	Neighborhood
BP	GO:0022402	cell cycle process	IEP	Neighborhood
CC	GO:0030312	external encapsulating structure	IEP	Neighborhood
MF	GO:0030332	cyclin binding	IEP	Neighborhood
BP	GO:0031323	regulation of cellular metabolic process	IEP	Neighborhood
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Neighborhood
BP	GO:0031400	negative regulation of protein modification process	IEP	Neighborhood
BP	GO:0032200	telomere organization	IEP	Neighborhood
BP	GO:0032204	regulation of telomere maintenance	IEP	Neighborhood
BP	GO:0032269	negative regulation of cellular protein metabolic process	IEP	Neighborhood
BP	GO:0032502	developmental process	IEP	Neighborhood
BP	GO:0032506	cytokinetic process	IEP	Neighborhood
BP	GO:0033043	regulation of organelle organization	IEP	Neighborhood
BP	GO:0033044	regulation of chromosome organization	IEP	Neighborhood
BP	GO:0033673	negative regulation of kinase activity	IEP	Neighborhood
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Neighborhood
BP	GO:0035194	posttranscriptional gene silencing by RNA	IEP	Neighborhood
BP	GO:0040020	regulation of meiotic nuclear division	IEP	Neighborhood
BP	GO:0042023	DNA endoreduplication	IEP	Neighborhood
BP	GO:0042325	regulation of phosphorylation	IEP	Neighborhood
BP	GO:0042326	negative regulation of phosphorylation	IEP	Neighborhood
MF	GO:0042623	ATPase activity, coupled	IEP	Neighborhood
BP	GO:0043086	negative regulation of catalytic activity	IEP	Neighborhood
CC	GO:0043226	organelle	IEP	Neighborhood
CC	GO:0043227	membrane-bounded organelle	IEP	Neighborhood
CC	GO:0043229	intracellular organelle	IEP	Neighborhood
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Neighborhood
BP	GO:0043247	telomere maintenance in response to DNA damage	IEP	Neighborhood
BP	GO:0043549	regulation of kinase activity	IEP	Neighborhood
BP	GO:0044092	negative regulation of molecular function	IEP	Neighborhood
BP	GO:0044249	cellular biosynthetic process	IEP	Neighborhood
CC	GO:0044424	intracellular part	IEP	Neighborhood
CC	GO:0044427	chromosomal part	IEP	Neighborhood
CC	GO:0044454	nuclear chromosome part	IEP	Neighborhood
BP	GO:0044786	cell cycle DNA replication	IEP	Neighborhood
BP	GO:0045128	negative regulation of reciprocal meiotic recombination	IEP	Neighborhood
BP	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	IEP	Neighborhood
BP	GO:0045786	negative regulation of cell cycle	IEP	Neighborhood
BP	GO:0045835	negative regulation of meiotic nuclear division	IEP	Neighborhood
BP	GO:0045859	regulation of protein kinase activity	IEP	Neighborhood
BP	GO:0045910	negative regulation of DNA recombination	IEP	Neighborhood
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Neighborhood
BP	GO:0045936	negative regulation of phosphate metabolic process	IEP	Neighborhood
BP	GO:0048285	organelle fission	IEP	Neighborhood
BP	GO:0048519	negative regulation of biological process	IEP	Neighborhood
BP	GO:0048523	negative regulation of cellular process	IEP	Neighborhood
BP	GO:0050789	regulation of biological process	IEP	Neighborhood
BP	GO:0050794	regulation of cellular process	IEP	Neighborhood
BP	GO:0051052	regulation of DNA metabolic process	IEP	Neighborhood
BP	GO:0051053	negative regulation of DNA metabolic process	IEP	Neighborhood
BP	GO:0051128	regulation of cellular component organization	IEP	Neighborhood
BP	GO:0051129	negative regulation of cellular component organization	IEP	Neighborhood
BP	GO:0051171	regulation of nitrogen compound metabolic process	IEP	Neighborhood
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Neighborhood
BP	GO:0051225	spindle assembly	IEP	Neighborhood
BP	GO:0051248	negative regulation of protein metabolic process	IEP	Neighborhood
BP	GO:0051338	regulation of transferase activity	IEP	Neighborhood
BP	GO:0051348	negative regulation of transferase activity	IEP	Neighborhood
BP	GO:0051445	regulation of meiotic cell cycle	IEP	Neighborhood
BP	GO:0051447	negative regulation of meiotic cell cycle	IEP	Neighborhood
BP	GO:0051726	regulation of cell cycle	IEP	Neighborhood
BP	GO:0051783	regulation of nuclear division	IEP	Neighborhood
BP	GO:0051784	negative regulation of nuclear division	IEP	Neighborhood
MF	GO:0060089	molecular transducer activity	IEP	Neighborhood
BP	GO:0060249	anatomical structure homeostasis	IEP	Neighborhood
BP	GO:0060255	regulation of macromolecule metabolic process	IEP	Neighborhood
BP	GO:0060631	regulation of meiosis I	IEP	Neighborhood
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Neighborhood
MF	GO:0061731	ribonucleoside-diphosphate reductase activity	IEP	Neighborhood
BP	GO:0065007	biological regulation	IEP	Neighborhood
MF	GO:0070035	purine NTP-dependent helicase activity	IEP	Neighborhood
BP	GO:0070925	organelle assembly	IEP	Neighborhood
BP	GO:0071900	regulation of protein serine/threonine kinase activity	IEP	Neighborhood
BP	GO:0071901	negative regulation of protein serine/threonine kinase activity	IEP	Neighborhood
BP	GO:0080090	regulation of primary metabolic process	IEP	Neighborhood
MF	GO:0097472	cyclin-dependent protein kinase activity	IEP	Neighborhood
BP	GO:0110029	negative regulation of meiosis I	IEP	Neighborhood
BP	GO:1901576	organic substance biosynthetic process	IEP	Neighborhood
BP	GO:1901987	regulation of cell cycle phase transition	IEP	Neighborhood
BP	GO:1901990	regulation of mitotic cell cycle phase transition	IEP	Neighborhood
BP	GO:1902410	mitotic cytokinetic process	IEP	Neighborhood
CC	GO:1902554	serine/threonine protein kinase complex	IEP	Neighborhood
BP	GO:1902749	regulation of cell cycle G2/M phase transition	IEP	Neighborhood
CC	GO:1902911	protein kinase complex	IEP	Neighborhood
BP	GO:1903047	mitotic cell cycle process	IEP	Neighborhood
BP	GO:1904029	regulation of cyclin-dependent protein kinase activity	IEP	Neighborhood
BP	GO:1904030	negative regulation of cyclin-dependent protein kinase activity	IEP	Neighborhood
BP	GO:2000242	negative regulation of reproductive process	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR001357	BRCT_dom	841	938
IPR001357	BRCT_dom	734	806

External Links

No external refs found!

AT4G21070 (BRCA1, ATBRCA1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation