AT4G35520 (ATMLH3, MLH3)

Aliases : ATMLH3, MLH3

Description : MUTL protein homolog 3

Gene families : OG0004225 (Archaeplastida) Phylogenetic Tree(s): OG0004225_tree ,
OG_05_0004690 (LandPlants) Phylogenetic Tree(s): OG_05_0004690_tree ,
OG_06_0005017 (SeedPlants) Phylogenetic Tree(s): OG_06_0005017_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AT4G35520
Cluster	HCCA: Cluster_176

Type	GO Term	Name	Evidence	Source
BP	GO:0000003	reproduction	None	Extended
MF	GO:0000166	nucleotide binding	None	Extended
BP	GO:0000723	telomere maintenance	None	Extended
CC	GO:0000795	synaptonemal complex	IBA	Interproscan
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	ISS	Interproscan
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	ISM	Interproscan
CC	GO:0005694	chromosome	IDA	Interproscan
CC	GO:0005712	chiasma	IBA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	ISS	Interproscan
BP	GO:0006298	mismatch repair	IBA	Interproscan
BP	GO:0006310	DNA recombination	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0007059	chromosome segregation	RCA	Interproscan
BP	GO:0007062	sister chromatid cohesion	RCA	Interproscan
BP	GO:0007129	synapsis	RCA	Interproscan
BP	GO:0007131	reciprocal meiotic recombination	IMP	Interproscan
BP	GO:0007131	reciprocal meiotic recombination	RCA	Interproscan
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009308	amine metabolic process	None	Extended
BP	GO:0009314	response to radiation	None	Extended
BP	GO:0009628	response to abiotic stimulus	None	Extended
BP	GO:0009690	cytokinin metabolic process	None	Extended
BP	GO:0009691	cytokinin biosynthetic process	RCA	Interproscan
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010212	response to ionizing radiation	None	Extended
BP	GO:0010332	response to gamma radiation	RCA	Interproscan
BP	GO:0010817	regulation of hormone levels	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IBA	Interproscan
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0022402	cell cycle process	None	Extended
BP	GO:0022414	reproductive process	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IBA	Interproscan
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0032200	telomere organization	None	Extended
BP	GO:0032204	regulation of telomere maintenance	RCA	Interproscan
CC	GO:0032300	mismatch repair complex	None	Extended
CC	GO:0032390	MutLbeta complex	IBA	Interproscan
BP	GO:0032501	multicellular organismal process	None	Extended
BP	GO:0032504	multicellular organism reproduction	RCA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0033043	regulation of organelle organization	None	Extended
BP	GO:0033044	regulation of chromosome organization	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034754	cellular hormone metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
BP	GO:0035825	homologous recombination	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0042138	meiotic DNA double-strand break formation	RCA	Interproscan
BP	GO:0042445	hormone metabolic process	None	Extended
BP	GO:0042446	hormone biosynthetic process	None	Extended
BP	GO:0042592	homeostatic process	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0043247	telomere maintenance in response to DNA damage	RCA	Interproscan
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044427	chromosomal part	None	Extended
CC	GO:0044428	nuclear part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044454	nuclear chromosome part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0045132	meiotic chromosome segregation	RCA	Interproscan
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051052	regulation of DNA metabolic process	None	Extended
BP	GO:0051128	regulation of cellular component organization	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0060249	anatomical structure homeostasis	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0061982	meiosis I cell cycle process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065008	regulation of biological quality	None	Extended
BP	GO:0070192	chromosome organization involved in meiotic cell cycle	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
BP	GO:0090305	nucleic acid phosphodiester bond hydrolysis	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
BP	GO:0098813	nuclear chromosome segregation	None	Extended
CC	GO:0099086	synaptonemal structure	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1903046	meiotic cell cycle process	None	Extended
CC	GO:1990391	DNA repair complex	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
BP	GO:0000280	nuclear division	IEP	Neighborhood
CC	GO:0000808	origin recognition complex	IEP	Neighborhood
MF	GO:0001067	regulatory region nucleic acid binding	IEP	Neighborhood
MF	GO:0001882	nucleoside binding	IEP	Neighborhood
MF	GO:0001883	purine nucleoside binding	IEP	Neighborhood
BP	GO:0002683	negative regulation of immune system process	IEP	Neighborhood
BP	GO:0002832	negative regulation of response to biotic stimulus	IEP	Neighborhood
MF	GO:0003700	DNA-binding transcription factor activity	IEP	Neighborhood
MF	GO:0004222	metalloendopeptidase activity	IEP	Neighborhood
MF	GO:0005525	GTP binding	IEP	Neighborhood
CC	GO:0005615	extracellular space	IEP	Neighborhood
BP	GO:0006089	lactate metabolic process	IEP	Neighborhood
BP	GO:0006260	DNA replication	IEP	Neighborhood
BP	GO:0006275	regulation of DNA replication	IEP	Neighborhood
BP	GO:0006304	DNA modification	IEP	Neighborhood
BP	GO:0006305	DNA alkylation	IEP	Neighborhood
BP	GO:0006306	DNA methylation	IEP	Neighborhood
BP	GO:0006325	chromatin organization	IEP	Neighborhood
BP	GO:0006338	chromatin remodeling	IEP	Neighborhood
BP	GO:0006355	regulation of transcription, DNA-templated	IEP	Neighborhood
BP	GO:0007140	male meiotic nuclear division	IEP	Neighborhood
MF	GO:0008083	growth factor activity	IEP	Neighborhood
MF	GO:0008170	N-methyltransferase activity	IEP	Neighborhood
MF	GO:0008270	zinc ion binding	IEP	Neighborhood
MF	GO:0008276	protein methyltransferase activity	IEP	Neighborhood
BP	GO:0008283	cell proliferation	IEP	Neighborhood
BP	GO:0008356	asymmetric cell division	IEP	Neighborhood
BP	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine	IEP	Neighborhood
BP	GO:0009438	methylglyoxal metabolic process	IEP	Neighborhood
BP	GO:0009560	embryo sac egg cell differentiation	IEP	Neighborhood
BP	GO:0009889	regulation of biosynthetic process	IEP	Neighborhood
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Neighborhood
BP	GO:0009900	dehiscence	IEP	Neighborhood
BP	GO:0009901	anther dehiscence	IEP	Neighborhood
BP	GO:0009956	radial pattern formation	IEP	Neighborhood
BP	GO:0010075	regulation of meristem growth	IEP	Neighborhood
BP	GO:0010082	regulation of root meristem growth	IEP	Neighborhood
BP	GO:0010112	regulation of systemic acquired resistance	IEP	Neighborhood
BP	GO:0010113	negative regulation of systemic acquired resistance	IEP	Neighborhood
MF	GO:0010385	double-stranded methylated DNA binding	IEP	Neighborhood
BP	GO:0010468	regulation of gene expression	IEP	Neighborhood
BP	GO:0010500	transmitting tissue development	IEP	Neighborhood
BP	GO:0010556	regulation of macromolecule biosynthetic process	IEP	Neighborhood
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Neighborhood
MF	GO:0016278	lysine N-methyltransferase activity	IEP	Neighborhood
MF	GO:0016279	protein-lysine N-methyltransferase activity	IEP	Neighborhood
BP	GO:0016569	covalent chromatin modification	IEP	Neighborhood
BP	GO:0016570	histone modification	IEP	Neighborhood
MF	GO:0018024	histone-lysine N-methyltransferase activity	IEP	Neighborhood
BP	GO:0018193	peptidyl-amino acid modification	IEP	Neighborhood
BP	GO:0018205	peptidyl-lysine modification	IEP	Neighborhood
MF	GO:0019001	guanyl nucleotide binding	IEP	Neighborhood
BP	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	IEP	Neighborhood
BP	GO:0022412	cellular process involved in reproduction in multicellular organism	IEP	Neighborhood
BP	GO:0030154	cell differentiation	IEP	Neighborhood
MF	GO:0030545	receptor regulator activity	IEP	Neighborhood
BP	GO:0031326	regulation of cellular biosynthetic process	IEP	Neighborhood
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Neighborhood
BP	GO:0031497	chromatin assembly	IEP	Neighborhood
BP	GO:0031507	heterochromatin assembly	IEP	Neighborhood
BP	GO:0032102	negative regulation of response to external stimulus	IEP	Neighborhood
BP	GO:0032502	developmental process	IEP	Neighborhood
BP	GO:0032507	maintenance of protein location in cell	IEP	Neighborhood
MF	GO:0032549	ribonucleoside binding	IEP	Neighborhood
MF	GO:0032550	purine ribonucleoside binding	IEP	Neighborhood
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Neighborhood
MF	GO:0042054	histone methyltransferase activity	IEP	Neighborhood
BP	GO:0042180	cellular ketone metabolic process	IEP	Neighborhood
BP	GO:0042182	ketone catabolic process	IEP	Neighborhood
BP	GO:0043901	negative regulation of multi-organism process	IEP	Neighborhood
MF	GO:0044212	transcription regulatory region DNA binding	IEP	Neighborhood
BP	GO:0044728	DNA methylation or demethylation	IEP	Neighborhood
BP	GO:0045185	maintenance of protein location	IEP	Neighborhood
BP	GO:0045787	positive regulation of cell cycle	IEP	Neighborhood
BP	GO:0045824	negative regulation of innate immune response	IEP	Neighborhood
BP	GO:0045892	negative regulation of transcription, DNA-templated	IEP	Neighborhood
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Neighborhood
BP	GO:0046185	aldehyde catabolic process	IEP	Neighborhood
MF	GO:0046976	histone methyltransferase activity (H3-K27 specific)	IEP	Neighborhood
MF	GO:0048018	receptor ligand activity	IEP	Neighborhood
BP	GO:0048285	organelle fission	IEP	Neighborhood
BP	GO:0048449	floral organ formation	IEP	Neighborhood
BP	GO:0048467	gynoecium development	IEP	Neighborhood
BP	GO:0048522	positive regulation of cellular process	IEP	Neighborhood
BP	GO:0050777	negative regulation of immune response	IEP	Neighborhood
BP	GO:0051252	regulation of RNA metabolic process	IEP	Neighborhood
BP	GO:0051253	negative regulation of RNA metabolic process	IEP	Neighborhood
BP	GO:0051457	maintenance of protein location in nucleus	IEP	Neighborhood
BP	GO:0051596	methylglyoxal catabolic process	IEP	Neighborhood
BP	GO:0051651	maintenance of location in cell	IEP	Neighborhood
BP	GO:0051726	regulation of cell cycle	IEP	Neighborhood
BP	GO:0061727	methylglyoxal catabolic process to lactate	IEP	Neighborhood
BP	GO:0070734	histone H3-K27 methylation	IEP	Neighborhood
BP	GO:0070828	heterochromatin organization	IEP	Neighborhood
BP	GO:0072595	maintenance of protein localization in organelle	IEP	Neighborhood
BP	GO:0140013	meiotic nuclear division	IEP	Neighborhood
MF	GO:0140110	transcription regulator activity	IEP	Neighborhood
BP	GO:1902679	negative regulation of RNA biosynthetic process	IEP	Neighborhood
BP	GO:1903506	regulation of nucleic acid-templated transcription	IEP	Neighborhood
BP	GO:1903507	negative regulation of nucleic acid-templated transcription	IEP	Neighborhood
BP	GO:1905393	plant organ formation	IEP	Neighborhood
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	IEP	Neighborhood
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Neighborhood
BP	GO:2001141	regulation of RNA biosynthetic process	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR014790	MutL_C	922	1097

External Links

No external refs found!

AT4G35520 (ATMLH3, MLH3)

Expression Profile

Co-expression Networks

Functional Annotation