GO:0016840: carbon-nitrogen lyase activity (Molecular function)

"Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99)." [EC:4.3.-.-]


There are 4953 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_17 Arabidopsis thaliana 1.75 % 0.003687 0.023198
Cluster_48 Arabidopsis thaliana 1.12 % 0.008744 0.032317
Cluster_32 Arabidopsis thaliana 0.91 % 0.013106 0.040671
Cluster_56 Amborella trichopoda 1.05 % 0.004146 0.042811
Cluster_8 Amborella trichopoda 1.47 % 0.002154 0.019195
Cluster_294 Zea mays 1.59 % 0.019523 0.046935
Cluster_251 Zea mays 2.25 % 0.000348 0.009136
Cluster_46 Zea mays 1.12 % 0.001394 0.021988
Cluster_72 Zea mays 2.15 % 0.00038 0.009245
Cluster_155 Marchantia polymorpha 2.08 % 0.012298 0.033064
Cluster_78 Picea abies 0.95 % 0.001826 0.008782
Cluster_137 Picea abies 1.56 % 2.6e-05 0.000259
Cluster_80 Oryza sativa 0.97 % 0.006159 0.029182
Cluster_76 Oryza sativa 1.33 % 0.000279 0.001616
Cluster_119 Selaginella moellendorffii 0.95 % 0.009401 0.037097
Cluster_201 Solanum lycopersicum 3.57 % 0.000355 0.011363
Cluster_97 Solanum lycopersicum 3.45 % 0.000381 0.010666
Cluster_21 Vitis vinifera 3.73 % 0.0 1e-06
Cluster_401 Vitis vinifera 50.0 % 0.002276 0.008346
Cluster_427 Vitis vinifera 50.0 % 0.002276 0.006828
Cluster_79 Chlamydomonas reinhardtii 1.43 % 0.015691 0.033243
Sequences (4953) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro Domains

Family Terms