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GO:0003712: transcription coregulator activity (Molecular function)

"A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators." [GOC:txnOH-2018, PMID:10213677, PMID:16858867, PMID:24203923, PMID:25957681, Wikipedia:Transcription_coregulator]


There are 6361 sequences with this label.

Enriched clusters
Name Species % in cluster p-value corrected p-value action
Cluster_58 Arabidopsis thaliana 1.4 % 0.010505 0.045686
Cluster_110 Arabidopsis thaliana 1.44 % 0.00995 0.025661
Cluster_116 Gingko biloba 0.97 % 0.006949 0.02823
Cluster_102 Gingko biloba 1.89 % 0.001883 0.02851
Cluster_219 Gingko biloba 3.9 % 1.4e-05 0.000824
Cluster_61 Zea mays 2.79 % 0.0 1e-06
Cluster_310 Zea mays 1.82 % 0.003068 0.033628
Cluster_262 Zea mays 1.64 % 0.003756 0.031145
Cluster_357 Zea mays 4.0 % 0.000645 0.021786
Cluster_125 Marchantia polymorpha 3.16 % 0.000122 0.00578
Cluster_178 Physcomitrella patens 1.82 % 0.018485 0.029207
Cluster_511 Picea abies 1.64 % 0.019951 0.039902
Cluster_1384 Picea abies 50.0 % 0.00066 0.00132
Cluster_212 Oryza sativa 1.18 % 0.006101 0.04271
Cluster_293 Oryza sativa 1.32 % 0.004849 0.019087
Cluster_40 Oryza sativa 1.52 % 0.00034 0.008997
Cluster_336 Oryza sativa 2.67 % 0.001227 0.026753
Cluster_217 Solanum lycopersicum 2.63 % 0.004178 0.044977
Cluster_291 Vitis vinifera 50.0 % 0.001594 0.014342
Sequences (6361) (download table)

Info: GO-associations disabled for items with more than 300 associated sequences !
InterPro and Family associations disabled for items with more than 5000 associated sequences !