Zm00001e022851_P002

Description : component PMS1 of MLH1-PMS1 heterodimer

Gene families : OG0004752 (Archaeplastida) Phylogenetic Tree(s): OG0004752_tree ,
OG_05_0004733 (LandPlants) Phylogenetic Tree(s): OG_05_0004733_tree ,
OG_06_0004714 (SeedPlants) Phylogenetic Tree(s): OG_06_0004714_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Zm00001e022851_P002
Cluster	HCCA: Cluster_250

Target	Alias	Description	ECC score	Gene Family Method
AT4G02460	PMS1	DNA mismatch repair protein, putative	0.03	Archaeplastida
Cpa\|evm.model.tig00000057.93	No alias	DNA mismatch repair protein PMS1 OS=Arabidopsis thaliana	0.03	Archaeplastida
Cre04.g227000	No alias	DNA damage response.DNA repair mechanisms.mismatch...	0.02	Archaeplastida
GSVIVT01027985001	No alias	DNA damage response.DNA repair mechanisms.mismatch...	0.07	Archaeplastida
LOC_Os02g37920.1	No alias	component PMS1 of MLH1-PMS1 heterodimer	0.07	Archaeplastida
Solyc09g074990.4.1	No alias	component PMS1 of MLH1-PMS1 heterodimer	0.04	Archaeplastida

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000151	ubiquitin ligase complex	IEP	Neighborhood
CC	GO:0000152	nuclear ubiquitin ligase complex	IEP	Neighborhood
BP	GO:0000726	non-recombinational repair	IEP	Neighborhood
CC	GO:0000775	chromosome, centromeric region	IEP	Neighborhood
BP	GO:0001522	pseudouridine synthesis	IEP	Neighborhood
MF	GO:0003678	DNA helicase activity	IEP	Neighborhood
MF	GO:0003682	chromatin binding	IEP	Neighborhood
MF	GO:0003697	single-stranded DNA binding	IEP	Neighborhood
MF	GO:0003723	RNA binding	IEP	Neighborhood
MF	GO:0003729	mRNA binding	IEP	Neighborhood
MF	GO:0003774	motor activity	IEP	Neighborhood
MF	GO:0003777	microtubule motor activity	IEP	Neighborhood
MF	GO:0003824	catalytic activity	IEP	Neighborhood
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Neighborhood
MF	GO:0003916	DNA topoisomerase activity	IEP	Neighborhood
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEP	Neighborhood
MF	GO:0003950	NAD+ ADP-ribosyltransferase activity	IEP	Neighborhood
MF	GO:0004386	helicase activity	IEP	Neighborhood
MF	GO:0004518	nuclease activity	IEP	Neighborhood
MF	GO:0005515	protein binding	IEP	Neighborhood
CC	GO:0005575	cellular_component	IEP	Neighborhood
CC	GO:0005634	nucleus	IEP	Neighborhood
CC	GO:0005643	nuclear pore	IEP	Neighborhood
CC	GO:0005680	anaphase-promoting complex	IEP	Neighborhood
CC	GO:0005685	U1 snRNP	IEP	Neighborhood
CC	GO:0005694	chromosome	IEP	Neighborhood
CC	GO:0005730	nucleolus	IEP	Neighborhood
BP	GO:0006260	DNA replication	IEP	Neighborhood
BP	GO:0006265	DNA topological change	IEP	Neighborhood
BP	GO:0006270	DNA replication initiation	IEP	Neighborhood
BP	GO:0006302	double-strand break repair	IEP	Neighborhood
BP	GO:0006303	double-strand break repair via nonhomologous end joining	IEP	Neighborhood
BP	GO:0006376	mRNA splice site selection	IEP	Neighborhood
BP	GO:0006471	protein ADP-ribosylation	IEP	Neighborhood
BP	GO:0006928	movement of cell or subcellular component	IEP	Neighborhood
BP	GO:0006996	organelle organization	IEP	Neighborhood
BP	GO:0007017	microtubule-based process	IEP	Neighborhood
BP	GO:0007018	microtubule-based movement	IEP	Neighborhood
BP	GO:0007059	chromosome segregation	IEP	Neighborhood
MF	GO:0008017	microtubule binding	IEP	Neighborhood
MF	GO:0008092	cytoskeletal protein binding	IEP	Neighborhood
MF	GO:0008094	DNA-dependent ATPase activity	IEP	Neighborhood
MF	GO:0008134	transcription factor binding	IEP	Neighborhood
CC	GO:0008287	protein serine/threonine phosphatase complex	IEP	Neighborhood
BP	GO:0009059	macromolecule biosynthetic process	IEP	Neighborhood
MF	GO:0009982	pseudouridine synthase activity	IEP	Neighborhood
BP	GO:0010639	negative regulation of organelle organization	IEP	Neighborhood
MF	GO:0015631	tubulin binding	IEP	Neighborhood
BP	GO:0016043	cellular component organization	IEP	Neighborhood
BP	GO:0016070	RNA metabolic process	IEP	Neighborhood
MF	GO:0016462	pyrophosphatase activity	IEP	Neighborhood
MF	GO:0016763	transferase activity, transferring pentosyl groups	IEP	Neighborhood
MF	GO:0016779	nucleotidyltransferase activity	IEP	Neighborhood
MF	GO:0016787	hydrolase activity	IEP	Neighborhood
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Neighborhood
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Neighborhood
MF	GO:0016853	isomerase activity	IEP	Neighborhood
MF	GO:0017056	structural constituent of nuclear pore	IEP	Neighborhood
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Neighborhood
MF	GO:0019208	phosphatase regulator activity	IEP	Neighborhood
MF	GO:0019888	protein phosphatase regulator activity	IEP	Neighborhood
BP	GO:0022402	cell cycle process	IEP	Neighborhood
BP	GO:0022618	ribonucleoprotein complex assembly	IEP	Neighborhood
CC	GO:0030289	protein phosphatase 4 complex	IEP	Neighborhood
CC	GO:0030532	small nuclear ribonucleoprotein complex	IEP	Neighborhood
CC	GO:0031461	cullin-RING ubiquitin ligase complex	IEP	Neighborhood
CC	GO:0032991	protein-containing complex	IEP	Neighborhood
BP	GO:0033043	regulation of organelle organization	IEP	Neighborhood
BP	GO:0033044	regulation of chromosome organization	IEP	Neighborhood
MF	GO:0034061	DNA polymerase activity	IEP	Neighborhood
BP	GO:0034645	cellular macromolecule biosynthetic process	IEP	Neighborhood
CC	GO:0042555	MCM complex	IEP	Neighborhood
BP	GO:0043086	negative regulation of catalytic activity	IEP	Neighborhood
MF	GO:0043138	3'-5' DNA helicase activity	IEP	Neighborhood
CC	GO:0043226	organelle	IEP	Neighborhood
CC	GO:0043227	membrane-bounded organelle	IEP	Neighborhood
CC	GO:0043229	intracellular organelle	IEP	Neighborhood
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Neighborhood
BP	GO:0044092	negative regulation of molecular function	IEP	Neighborhood
CC	GO:0044422	organelle part	IEP	Neighborhood
CC	GO:0044424	intracellular part	IEP	Neighborhood
CC	GO:0044428	nuclear part	IEP	Neighborhood
CC	GO:0044446	intracellular organelle part	IEP	Neighborhood
CC	GO:0044464	cell part	IEP	Neighborhood
BP	GO:0045132	meiotic chromosome segregation	IEP	Neighborhood
BP	GO:0050790	regulation of catalytic activity	IEP	Neighborhood
BP	GO:0051095	regulation of helicase activity	IEP	Neighborhood
BP	GO:0051097	negative regulation of helicase activity	IEP	Neighborhood
BP	GO:0051128	regulation of cellular component organization	IEP	Neighborhood
BP	GO:0051129	negative regulation of cellular component organization	IEP	Neighborhood
BP	GO:0051276	chromosome organization	IEP	Neighborhood
BP	GO:0051336	regulation of hydrolase activity	IEP	Neighborhood
BP	GO:0051346	negative regulation of hydrolase activity	IEP	Neighborhood
MF	GO:0061505	DNA topoisomerase II activity	IEP	Neighborhood
BP	GO:0065009	regulation of molecular function	IEP	Neighborhood
BP	GO:0071103	DNA conformation change	IEP	Neighborhood
BP	GO:0071826	ribonucleoprotein complex subunit organization	IEP	Neighborhood
BP	GO:0071840	cellular component organization or biogenesis	IEP	Neighborhood
CC	GO:0097525	spliceosomal snRNP complex	IEP	Neighborhood
CC	GO:0098687	chromosomal region	IEP	Neighborhood
BP	GO:0098813	nuclear chromosome segregation	IEP	Neighborhood
CC	GO:0120114	Sm-like protein family complex	IEP	Neighborhood
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Neighborhood
CC	GO:1902494	catalytic complex	IEP	Neighborhood
BP	GO:1903046	meiotic cell cycle process	IEP	Neighborhood
CC	GO:1903293	phosphatase complex	IEP	Neighborhood
BP	GO:1905462	regulation of DNA duplex unwinding	IEP	Neighborhood
BP	GO:1905463	negative regulation of DNA duplex unwinding	IEP	Neighborhood
BP	GO:1905774	regulation of DNA helicase activity	IEP	Neighborhood
BP	GO:1905775	negative regulation of DNA helicase activity	IEP	Neighborhood
BP	GO:2001251	negative regulation of chromosome organization	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR014790	MutL_C	780	937
IPR013507	DNA_mismatch_S5_2-like	228	346

External Links

No external refs found!

Zm00001e022851_P002

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation