Zm00001e036824_P001

Description : type-Ia DNA topoisomerase

Gene families : OG0003494 (Archaeplastida) Phylogenetic Tree(s): OG0003494_tree ,
OG_05_0003651 (LandPlants) Phylogenetic Tree(s): OG_05_0003651_tree ,
OG_06_0004734 (SeedPlants) Phylogenetic Tree(s): OG_06_0004734_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Zm00001e036824_P001
Cluster	HCCA: Cluster_180

Target	Alias	Description	ECC score	Gene Family Method
AMTR_s00006p00253660	evm_27.TU.AmTr_v1...	Cell cycle.organelle machineries.DNA replication.type-Ia...	0.08	Archaeplastida
AT4G31210	No alias	DNA topoisomerase, type IA, core	0.11	Archaeplastida
GSVIVT01035576001	No alias	Cell cycle.organelle machineries.DNA replication.type-Ia...	0.05	Archaeplastida
LOC_Os06g16980.1	No alias	type-Ia DNA topoisomerase	0.11	Archaeplastida
MA_10435445g0010	No alias	type-Ia DNA topoisomerase	0.02	Archaeplastida
Pp3c23_11430V3.1	No alias	DNA topoisomerase, type IA, core	0.04	Archaeplastida
Solyc02g081910.2.1	No alias	type-Ia DNA topoisomerase	0.04	Archaeplastida

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	Interproscan
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	IEA	Interproscan
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005694	chromosome	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Neighborhood
MF	GO:0001871	pattern binding	IEP	Neighborhood
MF	GO:0003723	RNA binding	IEP	Neighborhood
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Neighborhood
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Neighborhood
MF	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity	IEP	Neighborhood
MF	GO:0004177	aminopeptidase activity	IEP	Neighborhood
MF	GO:0004518	nuclease activity	IEP	Neighborhood
MF	GO:0004527	exonuclease activity	IEP	Neighborhood
MF	GO:0004540	ribonuclease activity	IEP	Neighborhood
MF	GO:0004645	phosphorylase activity	IEP	Neighborhood
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Neighborhood
MF	GO:0004832	valine-tRNA ligase activity	IEP	Neighborhood
MF	GO:0005524	ATP binding	IEP	Neighborhood
CC	GO:0005737	cytoplasm	IEP	Neighborhood
BP	GO:0006260	DNA replication	IEP	Neighborhood
BP	GO:0006418	tRNA aminoacylation for protein translation	IEP	Neighborhood
BP	GO:0006438	valyl-tRNA aminoacylation	IEP	Neighborhood
BP	GO:0006733	oxidoreduction coenzyme metabolic process	IEP	Neighborhood
MF	GO:0008094	DNA-dependent ATPase activity	IEP	Neighborhood
MF	GO:0008144	drug binding	IEP	Neighborhood
MF	GO:0008184	glycogen phosphorylase activity	IEP	Neighborhood
MF	GO:0008238	exopeptidase activity	IEP	Neighborhood
MF	GO:0008270	zinc ion binding	IEP	Neighborhood
MF	GO:0008408	3'-5' exonuclease activity	IEP	Neighborhood
MF	GO:0008987	quinolinate synthetase A activity	IEP	Neighborhood
BP	GO:0009058	biosynthetic process	IEP	Neighborhood
BP	GO:0009108	coenzyme biosynthetic process	IEP	Neighborhood
BP	GO:0009435	NAD biosynthetic process	IEP	Neighborhood
BP	GO:0016070	RNA metabolic process	IEP	Neighborhood
MF	GO:0016740	transferase activity	IEP	Neighborhood
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	IEP	Neighborhood
MF	GO:0016779	nucleotidyltransferase activity	IEP	Neighborhood
MF	GO:0016787	hydrolase activity	IEP	Neighborhood
MF	GO:0016788	hydrolase activity, acting on ester bonds	IEP	Neighborhood
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Neighborhood
BP	GO:0017038	protein import	IEP	Neighborhood
MF	GO:0017076	purine nucleotide binding	IEP	Neighborhood
BP	GO:0018130	heterocycle biosynthetic process	IEP	Neighborhood
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	IEP	Neighborhood
BP	GO:0019362	pyridine nucleotide metabolic process	IEP	Neighborhood
BP	GO:0019363	pyridine nucleotide biosynthetic process	IEP	Neighborhood
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Neighborhood
BP	GO:0019674	NAD metabolic process	IEP	Neighborhood
MF	GO:0030247	polysaccharide binding	IEP	Neighborhood
MF	GO:0030554	adenyl nucleotide binding	IEP	Neighborhood
MF	GO:0032553	ribonucleotide binding	IEP	Neighborhood
MF	GO:0032555	purine ribonucleotide binding	IEP	Neighborhood
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Neighborhood
MF	GO:0034061	DNA polymerase activity	IEP	Neighborhood
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Neighborhood
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Neighborhood
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Neighborhood
MF	GO:0036094	small molecule binding	IEP	Neighborhood
MF	GO:0042623	ATPase activity, coupled	IEP	Neighborhood
BP	GO:0043038	amino acid activation	IEP	Neighborhood
BP	GO:0043039	tRNA aminoacylation	IEP	Neighborhood
MF	GO:0043167	ion binding	IEP	Neighborhood
MF	GO:0043168	anion binding	IEP	Neighborhood
BP	GO:0044249	cellular biosynthetic process	IEP	Neighborhood
BP	GO:0044281	small molecule metabolic process	IEP	Neighborhood
BP	GO:0046496	nicotinamide nucleotide metabolic process	IEP	Neighborhood
MF	GO:0051539	4 iron, 4 sulfur cluster binding	IEP	Neighborhood
MF	GO:0061505	DNA topoisomerase II activity	IEP	Neighborhood
BP	GO:0072524	pyridine-containing compound metabolic process	IEP	Neighborhood
BP	GO:0072525	pyridine-containing compound biosynthetic process	IEP	Neighborhood
MF	GO:0097367	carbohydrate derivative binding	IEP	Neighborhood
MF	GO:0097747	RNA polymerase activity	IEP	Neighborhood
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Neighborhood
MF	GO:1901265	nucleoside phosphate binding	IEP	Neighborhood
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Neighborhood
BP	GO:1901576	organic substance biosynthetic process	IEP	Neighborhood
MF	GO:2001070	starch binding	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR006171	TOPRIM_domain	312	425
IPR025589	Toprim_C_rpt	979	1039
IPR013497	Topo_IA_cen	440	872
IPR013498	Topo_IA_Znf	915	950

External Links

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Zm00001e036824_P001

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation