AT4G02070 (MSH6-1, ATMSH6, MSH6)

Aliases : MSH6-1, ATMSH6, MSH6

Description : MUTS homolog 6

Gene families : OG0001515 (Archaeplastida) Phylogenetic Tree(s): OG0001515_tree ,
OG_05_0006028 (LandPlants) Phylogenetic Tree(s): OG_05_0006028_tree ,
OG_06_0005949 (SeedPlants) Phylogenetic Tree(s): OG_06_0005949_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AT4G02070
Cluster	HCCA: Cluster_75

Type	GO Term	Name	Evidence	Source
BP	GO:0000018	regulation of DNA recombination	None	Extended
MF	GO:0000217	DNA secondary structure binding	None	Extended
CC	GO:0000228	nuclear chromosome	IBA	Interproscan
MF	GO:0000400	four-way junction DNA binding	IBA	Interproscan
BP	GO:0000710	meiotic mismatch repair	IBA	Interproscan
BP	GO:0003006	developmental process involved in reproduction	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003684	damaged DNA binding	IDA	Interproscan
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IPI	Interproscan
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	ISM	Interproscan
CC	GO:0005694	chromosome	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006260	DNA replication	None	Extended
BP	GO:0006261	DNA-dependent DNA replication	RCA	Interproscan
BP	GO:0006270	DNA replication initiation	RCA	Interproscan
BP	GO:0006275	regulation of DNA replication	RCA	Interproscan
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006290	pyrimidine dimer repair	IMP	Interproscan
BP	GO:0006298	mismatch repair	ISS	Interproscan
BP	GO:0006310	DNA recombination	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0007131	reciprocal meiotic recombination	IBA	Interproscan
MF	GO:0008094	DNA-dependent ATPase activity	IBA	Interproscan
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009314	response to radiation	None	Extended
BP	GO:0009411	response to UV	IBA	Interproscan
BP	GO:0009416	response to light stimulus	None	Extended
BP	GO:0009628	response to abiotic stimulus	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0009892	negative regulation of metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0010605	negative regulation of macromolecule metabolic process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0022402	cell cycle process	None	Extended
BP	GO:0022414	reproductive process	None	Extended
MF	GO:0030983	mismatched DNA binding	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031324	negative regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
MF	GO:0032135	DNA insertion or deletion binding	None	Extended
MF	GO:0032137	guanine/thymine mispair binding	IBA	Interproscan
MF	GO:0032138	single base insertion or deletion binding	IBA	Interproscan
CC	GO:0032300	mismatch repair complex	None	Extended
CC	GO:0032301	MutSalpha complex	IBA	Interproscan
BP	GO:0032502	developmental process	None	Extended
CC	GO:0032991	protein-containing complex	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
BP	GO:0035825	homologous recombination	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0043570	maintenance of DNA repeat elements	IBA	Interproscan
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044422	organelle part	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044428	nuclear part	None	Extended
CC	GO:0044446	intracellular organelle part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0045910	negative regulation of DNA recombination	IBA	Interproscan
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0048449	floral organ formation	None	Extended
BP	GO:0048451	petal formation	RCA	Interproscan
BP	GO:0048453	sepal formation	RCA	Interproscan
BP	GO:0048519	negative regulation of biological process	None	Extended
BP	GO:0048523	negative regulation of cellular process	None	Extended
BP	GO:0048646	anatomical structure formation involved in morphogenesis	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051052	regulation of DNA metabolic process	None	Extended
BP	GO:0051053	negative regulation of DNA metabolic process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0051726	regulation of cell cycle	RCA	Interproscan
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0061982	meiosis I cell cycle process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
BP	GO:1903046	meiotic cell cycle process	None	Extended
BP	GO:1905393	plant organ formation	None	Extended
CC	GO:1990391	DNA repair complex	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Neighborhood
BP	GO:0000959	mitochondrial RNA metabolic process	IEP	Neighborhood
MF	GO:0001882	nucleoside binding	IEP	Neighborhood
MF	GO:0001883	purine nucleoside binding	IEP	Neighborhood
MF	GO:0003924	GTPase activity	IEP	Neighborhood
MF	GO:0004004	ATP-dependent RNA helicase activity	IEP	Neighborhood
MF	GO:0004067	asparaginase activity	IEP	Neighborhood
MF	GO:0004106	chorismate mutase activity	IEP	Neighborhood
MF	GO:0004143	diacylglycerol kinase activity	IEP	Neighborhood
MF	GO:0004372	glycine hydroxymethyltransferase activity	IEP	Neighborhood
MF	GO:0004842	ubiquitin-protein transferase activity	IEP	Neighborhood
MF	GO:0005221	intracellular cyclic nucleotide activated cation channel activity	IEP	Neighborhood
MF	GO:0005223	intracellular cGMP-activated cation channel activity	IEP	Neighborhood
MF	GO:0005522	profilin binding	IEP	Neighborhood
MF	GO:0005525	GTP binding	IEP	Neighborhood
CC	GO:0005769	early endosome	IEP	Neighborhood
CC	GO:0005788	endoplasmic reticulum lumen	IEP	Neighborhood
CC	GO:0005851	eukaryotic translation initiation factor 2B complex	IEP	Neighborhood
CC	GO:0005876	spindle microtubule	IEP	Neighborhood
CC	GO:0005938	cell cortex	IEP	Neighborhood
BP	GO:0006007	glucose catabolic process	IEP	Neighborhood
BP	GO:0006040	amino sugar metabolic process	IEP	Neighborhood
BP	GO:0006405	RNA export from nucleus	IEP	Neighborhood
BP	GO:0006406	mRNA export from nucleus	IEP	Neighborhood
BP	GO:0006446	regulation of translational initiation	IEP	Neighborhood
BP	GO:0006497	protein lipidation	IEP	Neighborhood
BP	GO:0006498	N-terminal protein lipidation	IEP	Neighborhood
BP	GO:0006499	N-terminal protein myristoylation	IEP	Neighborhood
BP	GO:0006516	glycoprotein catabolic process	IEP	Neighborhood
BP	GO:0006528	asparagine metabolic process	IEP	Neighborhood
BP	GO:0006530	asparagine catabolic process	IEP	Neighborhood
BP	GO:0006563	L-serine metabolic process	IEP	Neighborhood
BP	GO:0006661	phosphatidylinositol biosynthetic process	IEP	Neighborhood
BP	GO:0007026	negative regulation of microtubule depolymerization	IEP	Neighborhood
BP	GO:0007186	G-protein coupled receptor signaling pathway	IEP	Neighborhood
BP	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway	IEP	Neighborhood
MF	GO:0008017	microtubule binding	IEP	Neighborhood
MF	GO:0008092	cytoskeletal protein binding	IEP	Neighborhood
MF	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	IEP	Neighborhood
MF	GO:0008186	RNA-dependent ATPase activity	IEP	Neighborhood
MF	GO:0008780	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity	IEP	Neighborhood
BP	GO:0009056	catabolic process	IEP	Neighborhood
BP	GO:0009057	macromolecule catabolic process	IEP	Neighborhood
BP	GO:0009065	glutamine family amino acid catabolic process	IEP	Neighborhood
BP	GO:0009100	glycoprotein metabolic process	IEP	Neighborhood
BP	GO:0009895	negative regulation of catabolic process	IEP	Neighborhood
CC	GO:0010009	cytoplasmic side of endosome membrane	IEP	Neighborhood
BP	GO:0010212	response to ionizing radiation	IEP	Neighborhood
BP	GO:0010332	response to gamma radiation	IEP	Neighborhood
MF	GO:0015631	tubulin binding	IEP	Neighborhood
BP	GO:0015931	nucleobase-containing compound transport	IEP	Neighborhood
BP	GO:0016482	cytosolic transport	IEP	Neighborhood
MF	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	IEP	Neighborhood
MF	GO:0017076	purine nucleotide binding	IEP	Neighborhood
BP	GO:0018377	protein myristoylation	IEP	Neighborhood
MF	GO:0019001	guanyl nucleotide binding	IEP	Neighborhood
BP	GO:0019320	hexose catabolic process	IEP	Neighborhood
MF	GO:0019787	ubiquitin-like protein transferase activity	IEP	Neighborhood
BP	GO:0030581	symbiont intracellular protein transport in host	IEP	Neighborhood
BP	GO:0031048	chromatin silencing by small RNA	IEP	Neighborhood
BP	GO:0031110	regulation of microtubule polymerization or depolymerization	IEP	Neighborhood
BP	GO:0031111	negative regulation of microtubule polymerization or depolymerization	IEP	Neighborhood
BP	GO:0031114	regulation of microtubule depolymerization	IEP	Neighborhood
BP	GO:0031365	N-terminal protein amino acid modification	IEP	Neighborhood
BP	GO:0031647	regulation of protein stability	IEP	Neighborhood
MF	GO:0032182	ubiquitin-like protein binding	IEP	Neighborhood
BP	GO:0032507	maintenance of protein location in cell	IEP	Neighborhood
BP	GO:0032527	protein exit from endoplasmic reticulum	IEP	Neighborhood
MF	GO:0032549	ribonucleoside binding	IEP	Neighborhood
MF	GO:0032550	purine ribonucleoside binding	IEP	Neighborhood
MF	GO:0032553	ribonucleotide binding	IEP	Neighborhood
MF	GO:0032555	purine ribonucleotide binding	IEP	Neighborhood
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Neighborhood
BP	GO:0032886	regulation of microtubule-based process	IEP	Neighborhood
BP	GO:0033043	regulation of organelle organization	IEP	Neighborhood
BP	GO:0033345	asparagine catabolic process via L-aspartate	IEP	Neighborhood
MF	GO:0033549	MAP kinase phosphatase activity	IEP	Neighborhood
BP	GO:0035437	maintenance of protein localization in endoplasmic reticulum	IEP	Neighborhood
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Neighborhood
BP	GO:0042176	regulation of protein catabolic process	IEP	Neighborhood
BP	GO:0042177	negative regulation of protein catabolic process	IEP	Neighborhood
MF	GO:0043130	ubiquitin binding	IEP	Neighborhood
MF	GO:0043167	ion binding	IEP	Neighborhood
MF	GO:0043168	anion binding	IEP	Neighborhood
BP	GO:0043242	negative regulation of protein complex disassembly	IEP	Neighborhood
BP	GO:0043244	regulation of protein complex disassembly	IEP	Neighborhood
BP	GO:0043405	regulation of MAP kinase activity	IEP	Neighborhood
BP	GO:0043407	negative regulation of MAP kinase activity	IEP	Neighborhood
BP	GO:0043408	regulation of MAPK cascade	IEP	Neighborhood
BP	GO:0043409	negative regulation of MAPK cascade	IEP	Neighborhood
BP	GO:0043543	protein acylation	IEP	Neighborhood
MF	GO:0043855	cyclic nucleotide-gated ion channel activity	IEP	Neighborhood
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Neighborhood
BP	GO:0044282	small molecule catabolic process	IEP	Neighborhood
BP	GO:0044766	multi-organism transport	IEP	Neighborhood
BP	GO:0045022	early endosome to late endosome transport	IEP	Neighborhood
BP	GO:0045132	meiotic chromosome segregation	IEP	Neighborhood
BP	GO:0045185	maintenance of protein location	IEP	Neighborhood
BP	GO:0046165	alcohol biosynthetic process	IEP	Neighborhood
BP	GO:0046365	monosaccharide catabolic process	IEP	Neighborhood
BP	GO:0046488	phosphatidylinositol metabolic process	IEP	Neighborhood
BP	GO:0050657	nucleic acid transport	IEP	Neighborhood
BP	GO:0050658	RNA transport	IEP	Neighborhood
BP	GO:0050821	protein stabilization	IEP	Neighborhood
MF	GO:0051010	microtubule plus-end binding	IEP	Neighborhood
BP	GO:0051028	mRNA transport	IEP	Neighborhood
BP	GO:0051128	regulation of cellular component organization	IEP	Neighborhood
BP	GO:0051168	nuclear export	IEP	Neighborhood
BP	GO:0051235	maintenance of location	IEP	Neighborhood
BP	GO:0051236	establishment of RNA localization	IEP	Neighborhood
BP	GO:0051248	negative regulation of protein metabolic process	IEP	Neighborhood
BP	GO:0051493	regulation of cytoskeleton organization	IEP	Neighborhood
BP	GO:0051494	negative regulation of cytoskeleton organization	IEP	Neighborhood
BP	GO:0051651	maintenance of location in cell	IEP	Neighborhood
BP	GO:0051708	intracellular protein transport in other organism involved in symbiotic interaction	IEP	Neighborhood
BP	GO:0070507	regulation of microtubule cytoskeleton organization	IEP	Neighborhood
CC	GO:0071944	cell periphery	IEP	Neighborhood
BP	GO:0072329	monocarboxylic acid catabolic process	IEP	Neighborhood
BP	GO:0072595	maintenance of protein localization in organelle	IEP	Neighborhood
BP	GO:0080034	host response to induction by symbiont of tumor, nodule or growth in host	IEP	Neighborhood
MF	GO:0097367	carbohydrate derivative binding	IEP	Neighborhood
CC	GO:0098552	side of membrane	IEP	Neighborhood
CC	GO:0098562	cytoplasmic side of membrane	IEP	Neighborhood
BP	GO:0098813	nuclear chromosome segregation	IEP	Neighborhood
BP	GO:0098927	vesicle-mediated transport between endosomal compartments	IEP	Neighborhood
MF	GO:0099094	ligand-gated cation channel activity	IEP	Neighborhood
CC	GO:0099568	cytoplasmic region	IEP	Neighborhood
BP	GO:1900864	mitochondrial RNA modification	IEP	Neighborhood
MF	GO:1901265	nucleoside phosphate binding	IEP	Neighborhood
BP	GO:1901879	regulation of protein depolymerization	IEP	Neighborhood
BP	GO:1901880	negative regulation of protein depolymerization	IEP	Neighborhood
BP	GO:1902579	multi-organism localization	IEP	Neighborhood
BP	GO:1902581	multi-organism cellular localization	IEP	Neighborhood
BP	GO:1902583	multi-organism intracellular transport	IEP	Neighborhood
BP	GO:1902903	regulation of supramolecular fiber organization	IEP	Neighborhood
BP	GO:1902904	negative regulation of supramolecular fiber organization	IEP	Neighborhood
BP	GO:2001289	lipid X metabolic process	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR007861	DNA_mismatch_repair_MutS_clamp	886	976
IPR000432	DNA_mismatch_repair_MutS_C	1080	1270
IPR007696	DNA_mismatch_repair_MutS_core	701	1017
IPR007860	DNA_mmatch_repair_MutS_con_dom	506	667
IPR007695	DNA_mismatch_repair_MutS-lik_N	380	495

External Links

No external refs found!

AT4G02070 (MSH6-1, ATMSH6, MSH6)

Expression Profile

Co-expression Networks

Functional Annotation