AT5G63920 (AtTOP3alpha, TOP3A)


Aliases : AtTOP3alpha, TOP3A

Description : topoisomerase 3alpha


Gene families : OG0001504 (Archaeplastida) Phylogenetic Tree(s): OG0001504_tree ,
OG_05_0005827 (LandPlants) Phylogenetic Tree(s): OG_05_0005827_tree ,
OG_06_0006160 (SeedPlants) Phylogenetic Tree(s): OG_06_0006160_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood HRR: AT5G63920
Cluster HCCA: Cluster_166


Type GO Term Name Evidence Source
BP GO:0000712 resolution of meiotic recombination intermediates IMP Interproscan
MF GO:0003677 DNA binding ISS Interproscan
MF GO:0003916 DNA topoisomerase activity ISS Interproscan
CC GO:0005634 nucleus ISM Interproscan
BP GO:0006261 DNA-dependent DNA replication RCA Interproscan
BP GO:0006265 DNA topological change ISS Interproscan
BP GO:0006268 DNA unwinding involved in DNA replication ISS Interproscan
BP GO:0006270 DNA replication initiation RCA Interproscan
BP GO:0006275 regulation of DNA replication RCA Interproscan
BP GO:0006281 DNA repair IMP Interproscan
BP GO:0006306 DNA methylation RCA Interproscan
BP GO:0006342 chromatin silencing RCA Interproscan
BP GO:0007059 chromosome segregation IMP Interproscan
BP GO:0031047 gene silencing by RNA RCA Interproscan
BP GO:0048451 petal formation RCA Interproscan
BP GO:0048453 sepal formation RCA Interproscan
BP GO:0051567 histone H3-K9 methylation RCA Interproscan
BP GO:0051726 regulation of cell cycle RCA Interproscan
Type GO Term Name Evidence Source
BP GO:0000075 cell cycle checkpoint IEP Neighborhood
CC GO:0000151 ubiquitin ligase complex IEP Neighborhood
CC GO:0000152 nuclear ubiquitin ligase complex IEP Neighborhood
MF GO:0000166 nucleotide binding IEP Neighborhood
BP GO:0000226 microtubule cytoskeleton organization IEP Neighborhood
BP GO:0000278 mitotic cell cycle IEP Neighborhood
BP GO:0000280 nuclear division IEP Neighborhood
BP GO:0000724 double-strand break repair via homologous recombination IEP Neighborhood
BP GO:0000725 recombinational repair IEP Neighborhood
CC GO:0000785 chromatin IEP Neighborhood
CC GO:0000790 nuclear chromatin IEP Neighborhood
BP GO:0000911 cytokinesis by cell plate formation IEP Neighborhood
BP GO:0000919 cell plate assembly IEP Neighborhood
BP GO:0000959 mitochondrial RNA metabolic process IEP Neighborhood
BP GO:0002252 immune effector process IEP Neighborhood
BP GO:0002376 immune system process IEP Neighborhood
BP GO:0002683 negative regulation of immune system process IEP Neighborhood
BP GO:0002832 negative regulation of response to biotic stimulus IEP Neighborhood
MF GO:0003887 DNA-directed DNA polymerase activity IEP Neighborhood
MF GO:0003950 NAD+ ADP-ribosyltransferase activity IEP Neighborhood
MF GO:0004175 endopeptidase activity IEP Neighborhood
MF GO:0004402 histone acetyltransferase activity IEP Neighborhood
MF GO:0004407 histone deacetylase activity IEP Neighborhood
MF GO:0004633 phosphopantothenoylcysteine decarboxylase activity IEP Neighborhood
MF GO:0004674 protein serine/threonine kinase activity IEP Neighborhood
MF GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IEP Neighborhood
MF GO:0005524 ATP binding IEP Neighborhood
CC GO:0005680 anaphase-promoting complex IEP Neighborhood
CC GO:0005730 nucleolus IEP Neighborhood
CC GO:0005828 kinetochore microtubule IEP Neighborhood
CC GO:0005874 microtubule IEP Neighborhood
CC GO:0005876 spindle microtubule IEP Neighborhood
CC GO:0005971 ribonucleoside-diphosphate reductase complex IEP Neighborhood
BP GO:0006084 acetyl-CoA metabolic process IEP Neighborhood
BP GO:0006163 purine nucleotide metabolic process IEP Neighborhood
BP GO:0006220 pyrimidine nucleotide metabolic process IEP Neighborhood
BP GO:0006221 pyrimidine nucleotide biosynthetic process IEP Neighborhood
BP GO:0006271 DNA strand elongation involved in DNA replication IEP Neighborhood
BP GO:0006302 double-strand break repair IEP Neighborhood
BP GO:0006310 DNA recombination IEP Neighborhood
BP GO:0006333 chromatin assembly or disassembly IEP Neighborhood
BP GO:0006338 chromatin remodeling IEP Neighborhood
BP GO:0006471 protein ADP-ribosylation IEP Neighborhood
BP GO:0006476 protein deacetylation IEP Neighborhood
BP GO:0006508 proteolysis IEP Neighborhood
BP GO:0006521 regulation of cellular amino acid metabolic process IEP Neighborhood
BP GO:0006637 acyl-CoA metabolic process IEP Neighborhood
BP GO:0006753 nucleoside phosphate metabolic process IEP Neighborhood
BP GO:0006793 phosphorus metabolic process IEP Neighborhood
BP GO:0006796 phosphate-containing compound metabolic process IEP Neighborhood
BP GO:0006955 immune response IEP Neighborhood
BP GO:0007010 cytoskeleton organization IEP Neighborhood
BP GO:0007017 microtubule-based process IEP Neighborhood
BP GO:0007049 cell cycle IEP Neighborhood
BP GO:0007093 mitotic cell cycle checkpoint IEP Neighborhood
BP GO:0007129 synapsis IEP Neighborhood
BP GO:0007131 reciprocal meiotic recombination IEP Neighborhood
BP GO:0007140 male meiotic nuclear division IEP Neighborhood
BP GO:0007143 female meiotic nuclear division IEP Neighborhood
BP GO:0007166 cell surface receptor signaling pathway IEP Neighborhood
BP GO:0007167 enzyme linked receptor protein signaling pathway IEP Neighborhood
BP GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEP Neighborhood
BP GO:0007267 cell-cell signaling IEP Neighborhood
BP GO:0007346 regulation of mitotic cell cycle IEP Neighborhood
BP GO:0007389 pattern specification process IEP Neighborhood
MF GO:0008094 DNA-dependent ATPase activity IEP Neighborhood
MF GO:0008144 drug binding IEP Neighborhood
BP GO:0008283 cell proliferation IEP Neighborhood
CC GO:0008290 F-actin capping protein complex IEP Neighborhood
BP GO:0009117 nucleotide metabolic process IEP Neighborhood
BP GO:0009150 purine ribonucleotide metabolic process IEP Neighborhood
BP GO:0009165 nucleotide biosynthetic process IEP Neighborhood
BP GO:0009200 deoxyribonucleoside triphosphate metabolic process IEP Neighborhood
BP GO:0009202 deoxyribonucleoside triphosphate biosynthetic process IEP Neighborhood
BP GO:0009218 pyrimidine ribonucleotide metabolic process IEP Neighborhood
BP GO:0009220 pyrimidine ribonucleotide biosynthetic process IEP Neighborhood
BP GO:0009259 ribonucleotide metabolic process IEP Neighborhood
BP GO:0009555 pollen development IEP Neighborhood
BP GO:0009560 embryo sac egg cell differentiation IEP Neighborhood
BP GO:0009615 response to virus IEP Neighborhood
BP GO:0009616 virus induced gene silencing IEP Neighborhood
BP GO:0009799 specification of symmetry IEP Neighborhood
BP GO:0009855 determination of bilateral symmetry IEP Neighborhood
BP GO:0009909 regulation of flower development IEP Neighborhood
BP GO:0010014 meristem initiation IEP Neighborhood
BP GO:0010050 vegetative phase change IEP Neighborhood
BP GO:0010071 root meristem specification IEP Neighborhood
BP GO:0010073 meristem maintenance IEP Neighborhood
BP GO:0010075 regulation of meristem growth IEP Neighborhood
BP GO:0010082 regulation of root meristem growth IEP Neighborhood
BP GO:0010112 regulation of systemic acquired resistance IEP Neighborhood
BP GO:0010113 negative regulation of systemic acquired resistance IEP Neighborhood
MF GO:0010181 FMN binding IEP Neighborhood
BP GO:0010212 response to ionizing radiation IEP Neighborhood
BP GO:0010267 production of ta-siRNAs involved in RNA interference IEP Neighborhood
BP GO:0010364 regulation of ethylene biosynthetic process IEP Neighborhood
BP GO:0010452 histone H3-K36 methylation IEP Neighborhood
MF GO:0010485 H4 histone acetyltransferase activity IEP Neighborhood
BP GO:0010564 regulation of cell cycle process IEP Neighborhood
BP GO:0015936 coenzyme A metabolic process IEP Neighborhood
BP GO:0015937 coenzyme A biosynthetic process IEP Neighborhood
BP GO:0016444 somatic cell DNA recombination IEP Neighborhood
BP GO:0016575 histone deacetylation IEP Neighborhood
MF GO:0016725 oxidoreductase activity, acting on CH or CH2 groups IEP Neighborhood
MF GO:0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor IEP Neighborhood
MF GO:0017076 purine nucleotide binding IEP Neighborhood
MF GO:0019213 deacetylase activity IEP Neighborhood
BP GO:0019693 ribose phosphate metabolic process IEP Neighborhood
BP GO:0022412 cellular process involved in reproduction in multicellular organism IEP Neighborhood
BP GO:0022616 DNA strand elongation IEP Neighborhood
BP GO:0023052 signaling IEP Neighborhood
BP GO:0030036 actin cytoskeleton organization IEP Neighborhood
BP GO:0030422 production of siRNA involved in RNA interference IEP Neighborhood
MF GO:0030554 adenyl nucleotide binding IEP Neighborhood
BP GO:0030834 regulation of actin filament depolymerization IEP Neighborhood
BP GO:0030835 negative regulation of actin filament depolymerization IEP Neighborhood
BP GO:0030837 negative regulation of actin filament polymerization IEP Neighborhood
BP GO:0031050 dsRNA fragmentation IEP Neighborhood
BP GO:0031333 negative regulation of protein complex assembly IEP Neighborhood
BP GO:0031335 regulation of sulfur amino acid metabolic process IEP Neighborhood
CC GO:0031461 cullin-RING ubiquitin ligase complex IEP Neighborhood
BP GO:0031497 chromatin assembly IEP Neighborhood
BP GO:0031507 heterochromatin assembly IEP Neighborhood
BP GO:0031567 mitotic cell size control checkpoint IEP Neighborhood
BP GO:0032102 negative regulation of response to external stimulus IEP Neighborhood
BP GO:0032272 negative regulation of protein polymerization IEP Neighborhood
BP GO:0032465 regulation of cytokinesis IEP Neighborhood
BP GO:0032467 positive regulation of cytokinesis IEP Neighborhood
BP GO:0032501 multicellular organismal process IEP Neighborhood
BP GO:0032506 cytokinetic process IEP Neighborhood
MF GO:0032553 ribonucleotide binding IEP Neighborhood
MF GO:0032555 purine ribonucleotide binding IEP Neighborhood
MF GO:0032559 adenyl ribonucleotide binding IEP Neighborhood
BP GO:0032886 regulation of microtubule-based process IEP Neighborhood
BP GO:0033043 regulation of organelle organization IEP Neighborhood
BP GO:0033238 regulation of cellular amine metabolic process IEP Neighborhood
MF GO:0033558 protein deacetylase activity IEP Neighborhood
BP GO:0033865 nucleoside bisphosphate metabolic process IEP Neighborhood
BP GO:0033866 nucleoside bisphosphate biosynthetic process IEP Neighborhood
BP GO:0033875 ribonucleoside bisphosphate metabolic process IEP Neighborhood
BP GO:0034030 ribonucleoside bisphosphate biosynthetic process IEP Neighborhood
BP GO:0034032 purine nucleoside bisphosphate metabolic process IEP Neighborhood
BP GO:0034033 purine nucleoside bisphosphate biosynthetic process IEP Neighborhood
MF GO:0034061 DNA polymerase activity IEP Neighborhood
MF GO:0034212 peptide N-acetyltransferase activity IEP Neighborhood
BP GO:0034654 nucleobase-containing compound biosynthetic process IEP Neighborhood
BP GO:0035196 production of miRNAs involved in gene silencing by miRNA IEP Neighborhood
BP GO:0035383 thioester metabolic process IEP Neighborhood
BP GO:0035601 protein deacylation IEP Neighborhood
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Neighborhood
BP GO:0035821 modification of morphology or physiology of other organism IEP Neighborhood
BP GO:0035825 homologous recombination IEP Neighborhood
MF GO:0036094 small molecule binding IEP Neighborhood
BP GO:0040008 regulation of growth IEP Neighborhood
BP GO:0042138 meiotic DNA double-strand break formation IEP Neighborhood
MF GO:0042623 ATPase activity, coupled IEP Neighborhood
BP GO:0042762 regulation of sulfur metabolic process IEP Neighborhood
MF GO:0043168 anion binding IEP Neighborhood
CC GO:0043228 non-membrane-bounded organelle IEP Neighborhood
CC GO:0043232 intracellular non-membrane-bounded organelle IEP Neighborhood
BP GO:0043242 negative regulation of protein complex disassembly IEP Neighborhood
BP GO:0043244 regulation of protein complex disassembly IEP Neighborhood
BP GO:0043603 cellular amide metabolic process IEP Neighborhood
BP GO:0043687 post-translational protein modification IEP Neighborhood
BP GO:0043901 negative regulation of multi-organism process IEP Neighborhood
BP GO:0044003 modification by symbiont of host morphology or physiology IEP Neighborhood
BP GO:0044271 cellular nitrogen compound biosynthetic process IEP Neighborhood
BP GO:0044419 interspecies interaction between organisms IEP Neighborhood
CC GO:0044427 chromosomal part IEP Neighborhood
CC GO:0044428 nuclear part IEP Neighborhood
CC GO:0044430 cytoskeletal part IEP Neighborhood
CC GO:0044454 nuclear chromosome part IEP Neighborhood
BP GO:0045087 innate immune response IEP Neighborhood
BP GO:0045787 positive regulation of cell cycle IEP Neighborhood
BP GO:0045824 negative regulation of innate immune response IEP Neighborhood
BP GO:0045930 negative regulation of mitotic cell cycle IEP Neighborhood
BP GO:0048229 gametophyte development IEP Neighborhood
BP GO:0048285 organelle fission IEP Neighborhood
BP GO:0048446 petal morphogenesis IEP Neighborhood
BP GO:0048509 regulation of meristem development IEP Neighborhood
BP GO:0048518 positive regulation of biological process IEP Neighborhood
BP GO:0048522 positive regulation of cellular process IEP Neighborhood
BP GO:0048580 regulation of post-embryonic development IEP Neighborhood
BP GO:0048638 regulation of developmental growth IEP Neighborhood
BP GO:0048829 root cap development IEP Neighborhood
BP GO:0048831 regulation of shoot system development IEP Neighborhood
BP GO:0050777 negative regulation of immune response IEP Neighborhood
BP GO:0050793 regulation of developmental process IEP Neighborhood
MF GO:0051011 microtubule minus-end binding IEP Neighborhood
BP GO:0051128 regulation of cellular component organization IEP Neighborhood
BP GO:0051239 regulation of multicellular organismal process IEP Neighborhood
BP GO:0051301 cell division IEP Neighborhood
BP GO:0051302 regulation of cell division IEP Neighborhood
BP GO:0051493 regulation of cytoskeleton organization IEP Neighborhood
BP GO:0051494 negative regulation of cytoskeleton organization IEP Neighborhood
BP GO:0051568 histone H3-K4 methylation IEP Neighborhood
BP GO:0051607 defense response to virus IEP Neighborhood
BP GO:0051693 actin filament capping IEP Neighborhood
BP GO:0051701 interaction with host IEP Neighborhood
BP GO:0051704 multi-organism process IEP Neighborhood
BP GO:0051781 positive regulation of cell division IEP Neighborhood
BP GO:0051817 modification of morphology or physiology of other organism involved in symbiotic interaction IEP Neighborhood
BP GO:0052018 modulation by symbiont of RNA levels in host IEP Neighborhood
BP GO:0052249 modulation of RNA levels in other organism involved in symbiotic interaction IEP Neighborhood
BP GO:0055086 nucleobase-containing small molecule metabolic process IEP Neighborhood
BP GO:0060236 regulation of mitotic spindle organization IEP Neighborhood
MF GO:0061731 ribonucleoside-diphosphate reductase activity IEP Neighborhood
MF GO:0061733 peptide-lysine-N-acetyltransferase activity IEP Neighborhood
BP GO:0070192 chromosome organization involved in meiotic cell cycle IEP Neighborhood
BP GO:0070507 regulation of microtubule cytoskeleton organization IEP Neighborhood
BP GO:0070646 protein modification by small protein removal IEP Neighborhood
BP GO:0070828 heterochromatin organization IEP Neighborhood
BP GO:0070918 production of small RNA involved in gene silencing by RNA IEP Neighborhood
BP GO:0072528 pyrimidine-containing compound biosynthetic process IEP Neighborhood
CC GO:0080008 Cul4-RING E3 ubiquitin ligase complex IEP Neighborhood
BP GO:0080156 mitochondrial mRNA modification IEP Neighborhood
BP GO:0090068 positive regulation of cell cycle process IEP Neighborhood
BP GO:0090224 regulation of spindle organization IEP Neighborhood
BP GO:0090305 nucleic acid phosphodiester bond hydrolysis IEP Neighborhood
MF GO:0097367 carbohydrate derivative binding IEP Neighborhood
BP GO:0098586 cellular response to virus IEP Neighborhood
BP GO:0098732 macromolecule deacylation IEP Neighborhood
CC GO:0099080 supramolecular complex IEP Neighborhood
CC GO:0099081 supramolecular polymer IEP Neighborhood
CC GO:0099512 supramolecular fiber IEP Neighborhood
CC GO:0099513 polymeric cytoskeletal fiber IEP Neighborhood
BP GO:0140013 meiotic nuclear division IEP Neighborhood
BP GO:1900864 mitochondrial RNA modification IEP Neighborhood
BP GO:1900908 regulation of olefin metabolic process IEP Neighborhood
BP GO:1900911 regulation of olefin biosynthetic process IEP Neighborhood
MF GO:1901265 nucleoside phosphate binding IEP Neighborhood
BP GO:1901293 nucleoside phosphate biosynthetic process IEP Neighborhood
BP GO:1901879 regulation of protein depolymerization IEP Neighborhood
BP GO:1901880 negative regulation of protein depolymerization IEP Neighborhood
BP GO:1902410 mitotic cytokinetic process IEP Neighborhood
CC GO:1902494 catalytic complex IEP Neighborhood
BP GO:1902904 negative regulation of supramolecular fiber organization IEP Neighborhood
BP GO:1903047 mitotic cell cycle process IEP Neighborhood
CC GO:1990234 transferase complex IEP Neighborhood
BP GO:2000026 regulation of multicellular organismal development IEP Neighborhood
BP GO:2000241 regulation of reproductive process IEP Neighborhood
BP GO:2000694 regulation of phragmoplast microtubule organization IEP Neighborhood
InterPro domains Description Start Stop
IPR013498 Topo_IA_Znf 640 677
IPR010666 Znf_GRF 805 844
IPR013497 Topo_IA_cen 172 592
IPR006171 TOPRIM_domain 12 155
No external refs found!