Cre01.g036050

Description : DNA damage response.DNA repair mechanisms.mismatch repair (MMR).MLH1-PMS1 heterodimer.MLH1 component

Gene families : OG0005285 (Archaeplastida) Phylogenetic Tree(s): OG0005285_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: Cre01.g036050
Cluster	HCCA: Cluster_88

Target	Alias	Description	ECC score	Gene Family Method	Actions
MA_10427871g0010	No alias	component MLH1 of MLH1-PMS1 heterodimer	0.02	Archaeplastida
Solyc04g045660.4.1	No alias	component MLH1 of MLH1-PMS1 heterodimer	0.03	Archaeplastida

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003690	double-stranded DNA binding	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	None	Extended
BP	GO:0006298	mismatch repair	IEA	Interproscan
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0030983	mismatched DNA binding	IEA	Interproscan
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000724	double-strand break repair via homologous recombination	IEP	Neighborhood
BP	GO:0000725	recombinational repair	IEP	Neighborhood
BP	GO:0000726	non-recombinational repair	IEP	Neighborhood
MF	GO:0003678	DNA helicase activity	IEP	Neighborhood
MF	GO:0003887	DNA-directed DNA polymerase activity	IEP	Neighborhood
MF	GO:0004003	ATP-dependent DNA helicase activity	IEP	Neighborhood
MF	GO:0004386	helicase activity	IEP	Neighborhood
MF	GO:0004518	nuclease activity	IEP	Neighborhood
MF	GO:0004519	endonuclease activity	IEP	Neighborhood
BP	GO:0006270	DNA replication initiation	IEP	Neighborhood
BP	GO:0006275	regulation of DNA replication	IEP	Neighborhood
BP	GO:0006302	double-strand break repair	IEP	Neighborhood
BP	GO:0006303	double-strand break repair via nonhomologous end joining	IEP	Neighborhood
BP	GO:0006310	DNA recombination	IEP	Neighborhood
BP	GO:0006497	protein lipidation	IEP	Neighborhood
BP	GO:0006505	GPI anchor metabolic process	IEP	Neighborhood
BP	GO:0006506	GPI anchor biosynthetic process	IEP	Neighborhood
BP	GO:0006643	membrane lipid metabolic process	IEP	Neighborhood
BP	GO:0006650	glycerophospholipid metabolic process	IEP	Neighborhood
BP	GO:0006661	phosphatidylinositol biosynthetic process	IEP	Neighborhood
BP	GO:0006664	glycolipid metabolic process	IEP	Neighborhood
MF	GO:0008026	ATP-dependent helicase activity	IEP	Neighborhood
MF	GO:0008094	DNA-dependent ATPase activity	IEP	Neighborhood
BP	GO:0008156	negative regulation of DNA replication	IEP	Neighborhood
BP	GO:0008654	phospholipid biosynthetic process	IEP	Neighborhood
BP	GO:0009247	glycolipid biosynthetic process	IEP	Neighborhood
BP	GO:0009890	negative regulation of biosynthetic process	IEP	Neighborhood
BP	GO:0009892	negative regulation of metabolic process	IEP	Neighborhood
BP	GO:0010558	negative regulation of macromolecule biosynthetic process	IEP	Neighborhood
BP	GO:0010605	negative regulation of macromolecule metabolic process	IEP	Neighborhood
MF	GO:0016787	hydrolase activity	IEP	Neighborhood
BP	GO:0031324	negative regulation of cellular metabolic process	IEP	Neighborhood
BP	GO:0031327	negative regulation of cellular biosynthetic process	IEP	Neighborhood
MF	GO:0034061	DNA polymerase activity	IEP	Neighborhood
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	IEP	Neighborhood
BP	GO:0045017	glycerolipid biosynthetic process	IEP	Neighborhood
BP	GO:0045934	negative regulation of nucleobase-containing compound metabolic process	IEP	Neighborhood
BP	GO:0046467	membrane lipid biosynthetic process	IEP	Neighborhood
BP	GO:0046474	glycerophospholipid biosynthetic process	IEP	Neighborhood
BP	GO:0046486	glycerolipid metabolic process	IEP	Neighborhood
BP	GO:0046488	phosphatidylinositol metabolic process	IEP	Neighborhood
BP	GO:0048478	replication fork protection	IEP	Neighborhood
BP	GO:0048519	negative regulation of biological process	IEP	Neighborhood
BP	GO:0048523	negative regulation of cellular process	IEP	Neighborhood
BP	GO:0051052	regulation of DNA metabolic process	IEP	Neighborhood
BP	GO:0051053	negative regulation of DNA metabolic process	IEP	Neighborhood
BP	GO:0051172	negative regulation of nitrogen compound metabolic process	IEP	Neighborhood
MF	GO:0070035	purine NTP-dependent helicase activity	IEP	Neighborhood
BP	GO:0090329	regulation of DNA-dependent DNA replication	IEP	Neighborhood
MF	GO:0140097	catalytic activity, acting on DNA	IEP	Neighborhood
BP	GO:1903509	liposaccharide metabolic process	IEP	Neighborhood
BP	GO:2000104	negative regulation of DNA-dependent DNA replication	IEP	Neighborhood
BP	GO:2000113	negative regulation of cellular macromolecule biosynthetic process	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR013507	DNA_mismatch_S5_2-like	250	379
IPR032189	Mlh1_C	675	1007

External Links

No external refs found!

Cre01.g036050

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation