AT4G11820 (FKP1, EMB2778, MVA1, HMGS)

Aliases : FKP1, EMB2778, MVA1, HMGS

Description : hydroxymethylglutaryl-CoA synthase / HMG-CoA synthase / 3-hydroxy-3-methylglutaryl coenzyme A synthase

Gene families : OG0002042 (Archaeplastida) Phylogenetic Tree(s): OG0002042_tree ,
OG_05_0002447 (LandPlants) Phylogenetic Tree(s): OG_05_0002447_tree ,
OG_06_0002351 (SeedPlants) Phylogenetic Tree(s): OG_06_0002351_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	HRR: AT4G11820
Cluster	HCCA: Cluster_223

Target	Alias	Description	ECC score	Gene Family Method
GSVIVT01019875001	No alias	Secondary metabolism.terpenoids.mevalonate...	0.05	Archaeplastida
Gb_11300	No alias	3-hydroxy-3-methylglutaryl-CoA synthase	0.04	Archaeplastida
Gb_11303	No alias	3-hydroxy-3-methylglutaryl-CoA synthase	0.03	Archaeplastida
Gb_16306	No alias	3-hydroxy-3-methylglutaryl-CoA synthase	0.03	Archaeplastida
MA_101113g0020	No alias	3-hydroxy-3-methylglutaryl-CoA synthase	0.05	Archaeplastida
Mp4g22640.1	No alias	3-hydroxy-3-methylglutaryl-CoA synthase	0.03	Archaeplastida
Smo179152	No alias	Secondary metabolism.terpenoids.mevalonate...	0.04	Archaeplastida
Solyc08g080170.3.1	No alias	3-hydroxy-3-methylglutaryl-CoA synthase	0.06	Archaeplastida
Zm00001e010191_P001	No alias	3-hydroxy-3-methylglutaryl-CoA synthase	0.04	Archaeplastida

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004421	hydroxymethylglutaryl-CoA synthase activity	IGI	Interproscan
MF	GO:0004421	hydroxymethylglutaryl-CoA synthase activity	ISS	Interproscan
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005739	mitochondrion	ISM	Interproscan
CC	GO:0005829	cytosol	IDA	Interproscan
CC	GO:0005911	cell-cell junction	None	Extended
BP	GO:0006084	acetyl-CoA metabolic process	RCA	Interproscan
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006163	purine nucleotide metabolic process	None	Extended
BP	GO:0006629	lipid metabolic process	None	Extended
BP	GO:0006637	acyl-CoA metabolic process	None	Extended
BP	GO:0006644	phospholipid metabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006732	coenzyme metabolic process	None	Extended
BP	GO:0006753	nucleoside phosphate metabolic process	None	Extended
BP	GO:0006790	sulfur compound metabolic process	None	Extended
BP	GO:0006793	phosphorus metabolic process	None	Extended
BP	GO:0006796	phosphate-containing compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008610	lipid biosynthetic process	None	Extended
BP	GO:0008654	phospholipid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009117	nucleotide metabolic process	None	Extended
BP	GO:0009150	purine ribonucleotide metabolic process	None	Extended
BP	GO:0009240	isopentenyl diphosphate biosynthetic process	None	Extended
BP	GO:0009259	ribonucleotide metabolic process	None	Extended
CC	GO:0009506	plasmodesma	IDA	Interproscan
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016746	transferase activity, transferring acyl groups	None	Extended
BP	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	TAS	Interproscan
BP	GO:0019637	organophosphate metabolic process	None	Extended
BP	GO:0019693	ribose phosphate metabolic process	None	Extended
CC	GO:0030054	cell junction	None	Extended
BP	GO:0033865	nucleoside bisphosphate metabolic process	None	Extended
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	None	Extended
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0035383	thioester metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0043603	cellular amide metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044255	cellular lipid metabolic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044444	cytoplasmic part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0046490	isopentenyl diphosphate metabolic process	None	Extended
MF	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	None	Extended
BP	GO:0051186	cofactor metabolic process	None	Extended
BP	GO:0055086	nucleobase-containing small molecule metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0072521	purine-containing compound metabolic process	None	Extended
BP	GO:0090407	organophosphate biosynthetic process	None	Extended
BP	GO:1901135	carbohydrate derivative metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0000036	acyl carrier activity	IEP	Neighborhood
BP	GO:0000038	very long-chain fatty acid metabolic process	IEP	Neighborhood
BP	GO:0000272	polysaccharide catabolic process	IEP	Neighborhood
CC	GO:0000322	storage vacuole	IEP	Neighborhood
CC	GO:0000323	lytic vacuole	IEP	Neighborhood
CC	GO:0000325	plant-type vacuole	IEP	Neighborhood
CC	GO:0000326	protein storage vacuole	IEP	Neighborhood
CC	GO:0000327	lytic vacuole within protein storage vacuole	IEP	Neighborhood
BP	GO:0000902	cell morphogenesis	IEP	Neighborhood
BP	GO:0000904	cell morphogenesis involved in differentiation	IEP	Neighborhood
BP	GO:0003006	developmental process involved in reproduction	IEP	Neighborhood
MF	GO:0003756	protein disulfide isomerase activity	IEP	Neighborhood
MF	GO:0003878	ATP citrate synthase activity	IEP	Neighborhood
MF	GO:0003985	acetyl-CoA C-acetyltransferase activity	IEP	Neighborhood
MF	GO:0003988	acetyl-CoA C-acyltransferase activity	IEP	Neighborhood
MF	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	IEP	Neighborhood
MF	GO:0004163	diphosphomevalonate decarboxylase activity	IEP	Neighborhood
MF	GO:0004312	fatty acid synthase activity	IEP	Neighborhood
MF	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity	IEP	Neighborhood
MF	GO:0004634	phosphopyruvate hydratase activity	IEP	Neighborhood
MF	GO:0005504	fatty acid binding	IEP	Neighborhood
CC	GO:0005747	mitochondrial respiratory chain complex I	IEP	Neighborhood
CC	GO:0005783	endoplasmic reticulum	IEP	Neighborhood
CC	GO:0005886	plasma membrane	IEP	Neighborhood
BP	GO:0006082	organic acid metabolic process	IEP	Neighborhood
BP	GO:0006085	acetyl-CoA biosynthetic process	IEP	Neighborhood
BP	GO:0006164	purine nucleotide biosynthetic process	IEP	Neighborhood
BP	GO:0006631	fatty acid metabolic process	IEP	Neighborhood
BP	GO:0006633	fatty acid biosynthetic process	IEP	Neighborhood
BP	GO:0006694	steroid biosynthetic process	IEP	Neighborhood
BP	GO:0006720	isoprenoid metabolic process	IEP	Neighborhood
BP	GO:0006721	terpenoid metabolic process	IEP	Neighborhood
BP	GO:0006722	triterpenoid metabolic process	IEP	Neighborhood
MF	GO:0008028	monocarboxylic acid transmembrane transporter activity	IEP	Neighborhood
BP	GO:0008202	steroid metabolic process	IEP	Neighborhood
BP	GO:0008299	isoprenoid biosynthetic process	IEP	Neighborhood
MF	GO:0008381	mechanosensitive ion channel activity	IEP	Neighborhood
BP	GO:0008643	carbohydrate transport	IEP	Neighborhood
BP	GO:0009108	coenzyme biosynthetic process	IEP	Neighborhood
BP	GO:0009152	purine ribonucleotide biosynthetic process	IEP	Neighborhood
BP	GO:0009165	nucleotide biosynthetic process	IEP	Neighborhood
BP	GO:0009260	ribonucleotide biosynthetic process	IEP	Neighborhood
CC	GO:0009346	citrate lyase complex	IEP	Neighborhood
CC	GO:0009505	plant-type cell wall	IEP	Neighborhood
CC	GO:0009507	chloroplast	IEP	Neighborhood
CC	GO:0009528	plastid inner membrane	IEP	Neighborhood
CC	GO:0009532	plastid stroma	IEP	Neighborhood
CC	GO:0009536	plastid	IEP	Neighborhood
CC	GO:0009570	chloroplast stroma	IEP	Neighborhood
BP	GO:0009581	detection of external stimulus	IEP	Neighborhood
BP	GO:0009582	detection of abiotic stimulus	IEP	Neighborhood
BP	GO:0009605	response to external stimulus	IEP	Neighborhood
BP	GO:0009612	response to mechanical stimulus	IEP	Neighborhood
BP	GO:0009628	response to abiotic stimulus	IEP	Neighborhood
BP	GO:0009653	anatomical structure morphogenesis	IEP	Neighborhood
BP	GO:0009735	response to cytokinin	IEP	Neighborhood
BP	GO:0009786	regulation of asymmetric cell division	IEP	Neighborhood
BP	GO:0009808	lignin metabolic process	IEP	Neighborhood
BP	GO:0009826	unidimensional cell growth	IEP	Neighborhood
BP	GO:0009834	plant-type secondary cell wall biogenesis	IEP	Neighborhood
BP	GO:0009846	pollen germination	IEP	Neighborhood
BP	GO:0009932	cell tip growth	IEP	Neighborhood
BP	GO:0010033	response to organic substance	IEP	Neighborhood
BP	GO:0010043	response to zinc ion	IEP	Neighborhood
BP	GO:0010817	regulation of hormone levels	IEP	Neighborhood
MF	GO:0015120	phosphoglycerate transmembrane transporter activity	IEP	Neighborhood
MF	GO:0015121	phosphoenolpyruvate:phosphate antiporter activity	IEP	Neighborhood
MF	GO:0015301	anion:anion antiporter activity	IEP	Neighborhood
MF	GO:0015355	secondary active monocarboxylate transmembrane transporter activity	IEP	Neighborhood
MF	GO:0015605	organophosphate ester transmembrane transporter activity	IEP	Neighborhood
BP	GO:0015713	phosphoglycerate transmembrane transport	IEP	Neighborhood
BP	GO:0015714	phosphoenolpyruvate transport	IEP	Neighborhood
BP	GO:0015718	monocarboxylic acid transport	IEP	Neighborhood
BP	GO:0015748	organophosphate ester transport	IEP	Neighborhood
CC	GO:0016020	membrane	IEP	Neighborhood
BP	GO:0016053	organic acid biosynthetic process	IEP	Neighborhood
BP	GO:0016104	triterpenoid biosynthetic process	IEP	Neighborhood
BP	GO:0016114	terpenoid biosynthetic process	IEP	Neighborhood
BP	GO:0016125	sterol metabolic process	IEP	Neighborhood
BP	GO:0016126	sterol biosynthetic process	IEP	Neighborhood
BP	GO:0016128	phytosteroid metabolic process	IEP	Neighborhood
BP	GO:0016129	phytosteroid biosynthetic process	IEP	Neighborhood
BP	GO:0016131	brassinosteroid metabolic process	IEP	Neighborhood
BP	GO:0016132	brassinosteroid biosynthetic process	IEP	Neighborhood
MF	GO:0016407	acetyltransferase activity	IEP	Neighborhood
MF	GO:0016408	C-acyltransferase activity	IEP	Neighborhood
MF	GO:0016453	C-acetyltransferase activity	IEP	Neighborhood
MF	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	IEP	Neighborhood
MF	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups	IEP	Neighborhood
MF	GO:0016829	lyase activity	IEP	Neighborhood
MF	GO:0016831	carboxy-lyase activity	IEP	Neighborhood
MF	GO:0016836	hydro-lyase activity	IEP	Neighborhood
MF	GO:0016860	intramolecular oxidoreductase activity	IEP	Neighborhood
MF	GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	IEP	Neighborhood
BP	GO:0017145	stem cell division	IEP	Neighborhood
BP	GO:0018130	heterocycle biosynthetic process	IEP	Neighborhood
BP	GO:0019321	pentose metabolic process	IEP	Neighborhood
BP	GO:0019438	aromatic compound biosynthetic process	IEP	Neighborhood
BP	GO:0019742	pentacyclic triterpenoid metabolic process	IEP	Neighborhood
BP	GO:0019745	pentacyclic triterpenoid biosynthetic process	IEP	Neighborhood
BP	GO:0019752	carboxylic acid metabolic process	IEP	Neighborhood
BP	GO:0022414	reproductive process	IEP	Neighborhood
MF	GO:0022836	gated channel activity	IEP	Neighborhood
CC	GO:0030964	NADH dehydrogenase complex	IEP	Neighborhood
MF	GO:0031406	carboxylic acid binding	IEP	Neighborhood
BP	GO:0032501	multicellular organismal process	IEP	Neighborhood
BP	GO:0032502	developmental process	IEP	Neighborhood
BP	GO:0032989	cellular component morphogenesis	IEP	Neighborhood
MF	GO:0033293	monocarboxylic acid binding	IEP	Neighborhood
BP	GO:0033866	nucleoside bisphosphate biosynthetic process	IEP	Neighborhood
BP	GO:0034030	ribonucleoside bisphosphate biosynthetic process	IEP	Neighborhood
BP	GO:0034033	purine nucleoside bisphosphate biosynthetic process	IEP	Neighborhood
BP	GO:0034219	carbohydrate transmembrane transport	IEP	Neighborhood
BP	GO:0034654	nucleobase-containing compound biosynthetic process	IEP	Neighborhood
BP	GO:0035384	thioester biosynthetic process	IEP	Neighborhood
BP	GO:0042335	cuticle development	IEP	Neighborhood
BP	GO:0042445	hormone metabolic process	IEP	Neighborhood
BP	GO:0042446	hormone biosynthetic process	IEP	Neighborhood
BP	GO:0042732	D-xylose metabolic process	IEP	Neighborhood
BP	GO:0042873	aldonate transmembrane transport	IEP	Neighborhood
MF	GO:0042879	aldonate transmembrane transporter activity	IEP	Neighborhood
MF	GO:0043177	organic acid binding	IEP	Neighborhood
BP	GO:0043436	oxoacid metabolic process	IEP	Neighborhood
BP	GO:0043604	amide biosynthetic process	IEP	Neighborhood
BP	GO:0044271	cellular nitrogen compound biosynthetic process	IEP	Neighborhood
BP	GO:0044272	sulfur compound biosynthetic process	IEP	Neighborhood
CC	GO:0044422	organelle part	IEP	Neighborhood
CC	GO:0044434	chloroplast part	IEP	Neighborhood
CC	GO:0044435	plastid part	IEP	Neighborhood
CC	GO:0044437	vacuolar part	IEP	Neighborhood
CC	GO:0044446	intracellular organelle part	IEP	Neighborhood
MF	GO:0044620	ACP phosphopantetheine attachment site binding	IEP	Neighborhood
CC	GO:0045271	respiratory chain complex I	IEP	Neighborhood
BP	GO:0045770	positive regulation of asymmetric cell division	IEP	Neighborhood
BP	GO:0046390	ribose phosphate biosynthetic process	IEP	Neighborhood
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Neighborhood
BP	GO:0048103	somatic stem cell division	IEP	Neighborhood
BP	GO:0048316	seed development	IEP	Neighborhood
BP	GO:0048588	developmental cell growth	IEP	Neighborhood
BP	GO:0048653	anther development	IEP	Neighborhood
BP	GO:0048829	root cap development	IEP	Neighborhood
BP	GO:0048856	anatomical structure development	IEP	Neighborhood
BP	GO:0048869	cellular developmental process	IEP	Neighborhood
BP	GO:0050896	response to stimulus	IEP	Neighborhood
BP	GO:0050982	detection of mechanical stimulus	IEP	Neighborhood
BP	GO:0051188	cofactor biosynthetic process	IEP	Neighborhood
MF	GO:0051192	prosthetic group binding	IEP	Neighborhood
BP	GO:0051302	regulation of cell division	IEP	Neighborhood
BP	GO:0051781	positive regulation of cell division	IEP	Neighborhood
BP	GO:0065008	regulation of biological quality	IEP	Neighborhood
BP	GO:0071616	acyl-CoA biosynthetic process	IEP	Neighborhood
BP	GO:0072522	purine-containing compound biosynthetic process	IEP	Neighborhood
MF	GO:0089721	phosphoenolpyruvate transmembrane transporter activity	IEP	Neighborhood
BP	GO:0098656	anion transmembrane transport	IEP	Neighborhood
MF	GO:0140104	molecular carrier activity	IEP	Neighborhood
BP	GO:1901137	carbohydrate derivative biosynthetic process	IEP	Neighborhood
BP	GO:1901264	carbohydrate derivative transport	IEP	Neighborhood
BP	GO:1901293	nucleoside phosphate biosynthetic process	IEP	Neighborhood
BP	GO:1901362	organic cyclic compound biosynthetic process	IEP	Neighborhood
MF	GO:1901505	carbohydrate derivative transmembrane transporter activity	IEP	Neighborhood
BP	GO:1901566	organonitrogen compound biosynthetic process	IEP	Neighborhood
BP	GO:1901615	organic hydroxy compound metabolic process	IEP	Neighborhood
BP	GO:1901617	organic hydroxy compound biosynthetic process	IEP	Neighborhood
BP	GO:1903825	organic acid transmembrane transport	IEP	Neighborhood
BP	GO:1905039	carboxylic acid transmembrane transport	IEP	Neighborhood

InterPro domains	Description	Start	Stop
IPR013746	HMG_CoA_synt_C_dom	120	396
IPR013528	HMG_CoA_synth_N	1	119

External Links

No external refs found!

AT4G11820 (FKP1, EMB2778, MVA1, HMGS)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation